Vitamin A derivative prevents immune cell exhaustion in brain tumors
Immune cells can become exhausted after prolonged exposure to cancer, gradually losing their ability to attack tumor cells.…
UNC researcher wins major grant to study the role of endoplasmic reticulum in T-cell metabolism
Jessica Thaxton, PhD, MsCR, associate professor in the Department of Cell Biology and Physiology at the UNC School…
UC Irvine researchers develop framework to make CAR T-cell therapy safer
CAR T-cell therapy has transformed cancer care, offering new hope to patients with aggressive blood cancers who once…
Genetic tool turns soft cancer cells into immune targets
Researchers at the USC Viterbi School of Engineering and Keck School of Medicine of USC have engineered a remarkable genetic tool that…
New study redefines high risk criteria for multiple myeloma
Researchers have found that with new treatments for multiple myeloma, a serious type of blood cancer, clinicians should…
Probiotic metabolite found to suppress melanoma tumor growth in mice
Immune checkpoint inhibitors like anti-PD-1 have transformed melanoma treatment, yet more than half of patients fail to respond…
AI-designed molecular switch uses caffeine to control engineered cells
For many of us, a warm cup of coffee is how we start our day. For Texas A&M…
Maternal screening could help prevent deadly forms of leukemia
A deadly form of leukemia may be stopped before it ever develops by introducing targeted maternal screening in…
Why H2N2 flu is back on the pandemic preparedness radar
Decades after H2N2 vanished from humans, declining immunity and persistent animal reservoirs are renewing calls for stockpile-ready vaccines…
Researchers uncover new mechanism linking metabolism, immunity, and skeletal health
Obesity alters bone health not only through increased body weight but also by reshaping the bone marrow environment.…
Scientists find unexpected immune pathways for mRNA cancer vaccines
The advent of mRNA vaccines against SARS-CoV-2 in 2020 changed the course of the COVID-19 pandemic. Now, the…
Mitochondrial activity keeps dendritic cells ready to fight disease
Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) show that active mitochondria maintain dendritic cells,…