Researchers uncover molecular pathway controlling bone resorption and tooth eruption
RUNX2 is best known as a master transcription factor of osteoblast differentiation. Mutations in, or haploinsufficiency of RUNX2…
New mathematical method maps gene roles across different species
Background Much of what we know about biology comes from animal models, particularly mice. Applying these insights to…
CSHL researchers find way to make immunotherapy effective against colorectal cancer
Colorectal cancer has become the leading cause of cancer-related death for people under 50. Its most common forms…
Salk scientists use DNA origami to track molecular movements
Scientists often describe life as a series of chemical reactions. Pallav Kosuri, PhD, describes life as movement. Chemical…
New method enables more precise labeling of protein-protein interactions in cancer-specific cells
Using a photochemically driven labeling technique, a Cornell University-led research group has devised a strategy for capturing cancer-specific…
Error by AI scribe during medical appointment leaves patient devastated
When Rebecca Green arrived for her first appointment with a urologist, she was asked whether she consented to…
Exhausted T cells balance graft tolerance and infection risk
A comprehensive new review examines the complex role of T cell exhaustion in organ transplantation, highlighting how this…
Microbial metabolites could help improve functional cure rates for hepatitis B
Chronic hepatitis B (CHB) remains a major global challenge. Current therapies suppress HBV but rarely achieve functional cure…
Researchers identify key barrier preventing self repair of heart cells
Specialized cells in our body make biological tradeoffs to do certain jobs. To support large and hardworking hearts…
Scientists discover master molecular switch for ginseng saponin production
Sanchi ginseng (Panax notoginseng) is a cornerstone of traditional Chinese medicine, prized for its saponins-bioactive compounds with anti-inflammatory,…
Study reveals how DNA misfolding causes congenital heart disease
Congenital heart disease is the most common birth defect, affecting approximately 1 in 100 babies born each year.…
New portable strip test accurately detects mosquito-borne viruses
A research team has developed a multisite bridging-mediated lateral flow immunoassay (mbLFIA) that enables highly sensitive, portable detection…