Chronic inflammation shapes cancer progression and immunotherapy response
Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs,…
Optimization of CAR T cells to destroy solid tumors
A team led by LMU physician Sebastian Kobold has found a way to allow the body’s immune system…
Osteoprotegerin links bone metabolism to cardiovascular disease
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Osteoprotegerin (OPG), a glycoprotein in the tumor…
Transcription factor HOXD13 drives melanoma growth and immune evasion
A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors’…
MHC class II marks stronger immune response and longer survival in ovarian cancer
A new study sheds light on why some patients with the most aggressive form of ovarian cancer respond…
New genetic model reveals role of keratin 8 in colorectal cancer development
Researchers at Ã…bo Akademi University have identified a new molecular change in patients with colorectal cancer and developed…
Tumor-targeted chimeric drug increases efficacy and limits side effects
Wistar scientists have combined a promising cancer therapy with a molecule that targets tumors to treat cancer more…
RNA micelles enable targeted chemotherapy without immune toxicity
A new study in mice hints at the potential to use tiny particles made with RNA molecules to…
Genetic ancestry influences tumor biology and survival in head and neck cancers
Genetic ancestry plays a key role in determining the behavior of head and neck tumors and may help…
New nanomaterial kills cancer cells via oxidative stress
Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside…
Moffitt researchers develop a new way to predict how cancer cells evolve
Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing…
Decoupling of metabolism and vasculature in tumors revealed by novel Capillary-Cell microscopy
A multidisciplinary team from Harvard Medical School, Duke University, and Massachusetts General Hospital has developed the dual-scale Capillary-Cell…