Missing ancestry data in single-cell atlases threatens fair medicine
The single-cell “atlases” that are increasingly used to map the human body and as training data for artificial…
New ctDNA blood test improves personalized prostate cancer treatment
A noninvasive DNA blood test can identify metastatic castration-resistant prostate cancer (mCRPC) patients who are most likely to…
LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53…
New biological feedback loop helps the immune system attack colorectal cancers
A subset of cancers, known as microsatellite instability (MSI) and deficient DNA mismatch repair (dMMR) cancers, are more…
Ketogenic diet may increase small intestine cancer risk in mice
A high-fat, low-carbohydrate diet, also called a ketogenic diet, can help some people lose weight by forcing their…
Study links gut microbes to stronger cancer immunotherapy responses
A new study from a team including University of Nebraska–Lincoln researchers is the first to show metabolites produced…
Integrating gene signatures and multi omics improves liver cancer treatment
Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers. Multi‑omics and liquid biopsy…
Study reports a counterintuitive new approach to treating mesothelioma
Mesothelioma is a rare but aggressive cancer, usually caused by exposure to asbestos. Inhaled asbestos fibers become lodged…
New therapy targets Hippo pathway to fight treatment-resistant acute myeloid leukemia
Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid…
New study explains how brain tumors evolve to resist treatment
A form of glioma, a type of brain cancer, tends to progress towards greater malignancy due to an…
Six-gene signature predicts colorectal cancer recurrence after liver metastases
Researchers at The University of Texas MD Anderson Cancer Center identified a six-gene signature in microscopic colorectal cancer…
Lung tumors hack the nervous system to cause severe cachexia
Cachexia is a condition in which patients affected by cancer or other chronic diseases become sick and lose…