Collaborative effort advances next-generation therapies for pancreatic and GI cancers
Last year, researchers at the University of California, Riverside, developed a novel “molecular crowbar” strategy to degrade the oncogenic enzyme…
New NIH grants fuel research in oral cancer treatment and pain relief
Researchers at the School of Dentistry at UT Health San Antonio, the academic health center of The University…
Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer
Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden…
Inflammation identified as a key driver in the earliest stages of lung cancer
By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The…
Trojan horse strategy using cesium nanosalts shows powerful anti-cancer effects
Recently, a team led by Academician Hongjie Zhang, Researcher Shuyan Song, Associate Researcher Pengpeng Lei, and Dr. Ran An…
Northwestern team develops antibody to expose hidden pancreatic cancer cells
Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…
precision DNA repair may hold clues for human aging
The bowhead whale’s remarkable lifespan and low cancer risk stem from a finely tuned DNA repair system driven…
Thiostrepton suppresses rhabdomyosarcoma progression by targeting the PI3K–AKT pathway
Rhabdomyosarcoma (RMS) accounts for up to 10% of childhood cancers and nearly half of pediatric soft tissue sarcomas.…
New chemotherapeutic agent shows remarkable efficacy against multiple tumor types
A research team led by the Medical University of Vienna, the HUN-REN Research Centre for Natural Sciences and…
Two microbial metabolites compete to control the cells’ protein building machinery
The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in…
Targeting myeloid cells to enhance cancer immunotherapy
Mayo Clinic researchers have identified a specific immune cell that can be targeted to give a boost to standard…