Homologous recombination deficiency and hemizygosity drive resistance in breast cancer
Study cohort and prospective sequencing The study cohort comprised 6,927 tumour samples from 5,881 patients with breast cancer.…
Elevated CD36 drives lymph node metastasis of breast cancer by activating Hippo-YAP signaling-mediated anoikis resistance
Bray, F. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers…
Meta-analysis reveals differences in somatic alterations by genetic ancestry across common cancers
Genetic ancestry is a quantitative measure of inherited genetic variation and correlates with human migration patterns1. It contributes…