Mitochondrial rewiring may explain why orthoflaviviruses harm humans but persist in mosquitoes
From mitochondrial fragmentation to antioxidant defenses, researchers reveal how the same viruses can drive cellular damage in vertebrates…
Researchers uncover hidden mechanism behind cancer-linked SPOP mutations
Mutations to the protein SPOP are widespread in cancer, yet many remain poorly understood. To address this gap,…
New viral library helps scientists study thousands of proteins
To prevent viruses from sickening or killing us – whether it’s an individual case of hepatitis B or…
Study elucidates key steps in the ubiquitin tagging of mutated huntingtin protein
Researchers have elucidated key steps in the ubiquitin tagging of the mutated huntingtin protein, providing hope for future…
Lactate and lactylation drive metabolic, epigenetic reprogramming in gynecological cancers
Lactate, once considered a metabolic waste product, is now recognized as a key regulator of cellular homeostasis and…