{"id":134297,"date":"2025-11-11T16:56:07","date_gmt":"2025-11-11T16:56:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/134297\/"},"modified":"2025-11-11T16:56:07","modified_gmt":"2025-11-11T16:56:07","slug":"concordance-of-cancer-associated-cytokines-and-mitochondrial-dna-deletions-in-individuals-with-hepatocellular-carcinoma-and-people-living-with-hiv-in-ghana-bmc-gastroenterology","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/134297\/","title":{"rendered":"Concordance of cancer-associated cytokines and mitochondrial DNA deletions in individuals with hepatocellular carcinoma and people living with HIV in Ghana | BMC Gastroenterology"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Bower M, Palmieri C, Stebbing J. AIDS associated malignancies. Update Cancer Ther. 2006;1(2):221\u201334.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=AIDS%20associated%20malignancies&amp;journal=Update%20Cancer%20Ther&amp;volume=1&amp;issue=2&amp;pages=221-34&amp;publication_year=2006&amp;author=Bower%2CM&amp;author=Palmieri%2CC&amp;author=Stebbing%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Franceschi S, Lise M, Clifford GM, Rickenbach M, Levi F, Maspoli M, et al. Changing patterns of cancer incidence in the early- and late-HAART periods: the Swiss HIV cohort study. Br J Cancer. 2010;103(3):416\u201322.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3cXpt1Oitrk%3D\" aria-label=\"CAS reference 2\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=20588274\" aria-label=\"PubMed reference 2\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2920013\" aria-label=\"PubMed Central reference 2\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Changing%20patterns%20of%20cancer%20incidence%20in%20the%20early-%20and%20late-HAART%20periods%3A%20the%20Swiss%20HIV%20cohort%20study&amp;journal=Br%20J%20Cancer&amp;volume=103&amp;issue=3&amp;pages=416-22&amp;publication_year=2010&amp;author=Franceschi%2CS&amp;author=Lise%2CM&amp;author=Clifford%2CGM&amp;author=Rickenbach%2CM&amp;author=Levi%2CF&amp;author=Maspoli%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Yuan T, Hu Y, Zhou X, Yang L, Wang H, Li L, et al. Incidence and mortality of non-AIDS-defining cancers among people living with HIV: A systematic review and meta-analysis. eClinicalMedicine. 2022;52:101613.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35990580\" aria-label=\"PubMed reference 3\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9386399\" aria-label=\"PubMed Central reference 3\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Incidence%20and%20mortality%20of%20non-AIDS-defining%20cancers%20among%20people%20living%20with%20HIV%3A%20A%20systematic%20review%20and%20meta-analysis&amp;journal=eClinicalMedicine&amp;volume=52&amp;publication_year=2022&amp;author=Yuan%2CT&amp;author=Hu%2CY&amp;author=Zhou%2CX&amp;author=Yang%2CL&amp;author=Wang%2CH&amp;author=Li%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Horner MJ, Shiels MS, Pfeiffer RM, Engels EA. Deaths attributable to cancer in the US human immunodeficiency virus population during 2001\u20132015. Clin Infect Dis. 2020;72(9):e224\u201331.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8096269\" aria-label=\"PubMed Central reference 4\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Deaths%20attributable%20to%20cancer%20in%20the%20US%20human%20immunodeficiency%20virus%20population%20during%202001%E2%80%932015&amp;journal=Clin%20Infect%20Dis&amp;volume=72&amp;issue=9&amp;pages=e224-31&amp;publication_year=2020&amp;author=Horner%2CMJ&amp;author=Shiels%2CMS&amp;author=Pfeiffer%2CRM&amp;author=Engels%2CEA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Smith CJ, Ryom L, Weber R, Morlat P, Pradier C, Reiss P, et al. Trends in underlying causes of death in people with HIV from 1999 to 2011 (D:A:D): a multicohort collaboration. Lancet. 2014;384(9939):241\u20138.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25042234\" aria-label=\"PubMed reference 5\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Trends%20in%20underlying%20causes%20of%20death%20in%20people%20with%20HIV%20from%201999%20to%202011%20%28D%3AA%3AD%29%3A%20a%20multicohort%20collaboration&amp;journal=Lancet&amp;volume=384&amp;issue=9939&amp;pages=241-8&amp;publication_year=2014&amp;author=Smith%2CCJ&amp;author=Ryom%2CL&amp;author=Weber%2CR&amp;author=Morlat%2CP&amp;author=Pradier%2CC&amp;author=Reiss%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">McGlynn KA, Petrick JL, El-Serag HB. Epidemiol Hepatocellular Carcinoma Hepatol. 2021;73(Suppl 1):4\u201313.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXms1Ggt7o%3D\" aria-label=\"CAS reference 6\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=&amp;journal=Epidemiol%20Hepatocellular%20Carcinoma%20Hepatol&amp;volume=73&amp;issue=Suppl%201&amp;pages=4-13&amp;publication_year=2021&amp;author=McGlynn%2CKA&amp;author=Petrick%2CJL&amp;author=El-Serag%2CHB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Frick C, Rumgay H, Vignat J, Ginsburg O, Nolte E, Bray F, et al. Quantitative estimates of preventable and treatable deaths from 36 cancers worldwide: a population-based study. Lancet Glob Health. 2023;11(11):e1700\u201312.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXitVSqt77N\" aria-label=\"CAS reference 7\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37774721\" aria-label=\"PubMed reference 7\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10581909\" aria-label=\"PubMed Central reference 7\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Quantitative%20estimates%20of%20preventable%20and%20treatable%20deaths%20from%2036%20cancers%20worldwide%3A%20a%20population-based%20study&amp;journal=Lancet%20Glob%20Health&amp;volume=11&amp;issue=11&amp;pages=e1700-12&amp;publication_year=2023&amp;author=Frick%2CC&amp;author=Rumgay%2CH&amp;author=Vignat%2CJ&amp;author=Ginsburg%2CO&amp;author=Nolte%2CE&amp;author=Bray%2CF\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Rumgay H, Ferlay J, de Martel C, Georges D, Ibrahim AS, Zheng R, et al. Global, regional and National burden of primary liver cancer by subtype. Eur J Cancer. 2022;161:108\u201318.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34942552\" aria-label=\"PubMed reference 8\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Global%2C%20regional%20and%20National%20burden%20of%20primary%20liver%20cancer%20by%20subtype&amp;journal=Eur%20J%20Cancer&amp;volume=161&amp;pages=108-18&amp;publication_year=2022&amp;author=Rumgay%2CH&amp;author=Ferlay%2CJ&amp;author=Martel%2CC&amp;author=Georges%2CD&amp;author=Ibrahim%2CAS&amp;author=Zheng%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Liver cancer statistics | World Cancer Research Fund International. WCRF International. Cited\u00a030 Jan 2023. Available from: <a href=\"https:\/\/www.wcrf.org\/cancer-trends\/liver-cancer-statistics\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.wcrf.org\/cancer-trends\/liver-cancer-statistics\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.wcrf.org\/cancer-trends\/liver-cancer-statistics\/<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Sun J, Althoff KN, Jing Y, Horberg MA, Buchacz K, Gill MJ et al. Trends in Hepatocellular Carcinoma Incidence and Risk Among Persons With HIV in the US and Canada, 1996\u20132015. JAMA Network Open. 2021;4(2).\u00a0Cited 15 Dec 2022. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7890526\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7890526\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7890526\/<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Mehershanhi S, Haider A, Kandhi S, Sun H, Patel H. Prevalence of hepatocellular carcinoma in HIV patients Co-infected or triple infected with hepatitis B and hepatitis C in a community hospital in South Bronx. Cureus 14(6):e26089.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Otedo A, Simbiri KO, Were V, Ongati O, Estambale BA. Risk factors for liver cancer in HIV endemic areas of Western Kenya. Infect Agent Cancer. 2018;13:41.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhs1Shu7%2FF\" aria-label=\"CAS reference 12\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30607173\" aria-label=\"PubMed reference 12\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6303973\" aria-label=\"PubMed Central reference 12\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Risk%20factors%20for%20liver%20cancer%20in%20HIV%20endemic%20areas%20of%20Western%20Kenya&amp;journal=Infect%20Agent%20Cancer&amp;volume=13&amp;publication_year=2018&amp;author=Otedo%2CA&amp;author=Simbiri%2CKO&amp;author=Were%2CV&amp;author=Ongati%2CO&amp;author=Estambale%2CBA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Mak D, de Villiers CB, Chasela C, Urban MI, Kramvis A. Analysis of risk factors associated with hepatocellular carcinoma in black South Africans: 2000\u20132012. PLoS ONE. 2018 ;13(5). Cited 13 Oct 2023. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5931658\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5931658\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5931658\/<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Nsibirwa SK, Aizire J, Thomas DL, Ocama P, Kirk GD. Rapid progression to death after hepatocellular carcinoma diagnosis particularly among persons with advanced HIV disease in Kampala, Uganda. medRxiv; 2022: 2022.06.24.22276850.\u00a0Cited 8 Nov 2022. Available from: <a href=\"https:\/\/www.medrxiv.org\/content\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.medrxiv.org\/content\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.medrxiv.org\/content\/<\/a><a href=\"https:\/\/doi.org\/10.1101\/2022.06.24.22276850v2\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/2022.06.24.22276850v2\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/2022.06.24.22276850v2<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">El-Shenawy R, Farouk S, Helmy N, Din NBE, El-Shenawy R, Farouk S et al. Risk Factors Associated with Development of Hepatocellular Carcinoma in Hepatitis C Virus Patients. In: Hepatitis C &#8211; Recent Advances. IntechOpen; 2023. Cited 19 Aug 2023. Available from: <a href=\"https:\/\/www.intechopen.com\/chapters\/1131136\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.intechopen.com\/chapters\/1131136\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.intechopen.com\/chapters\/1131136<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Global progress report on HIV. viral hepatitis and sexually transmitted infections, 2021. Cited 1 Apr 2023. Available from: <a href=\"https:\/\/www.who.int\/publications-detail-redirect\/9789240027077\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.who.int\/publications-detail-redirect\/9789240027077\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.who.int\/publications-detail-redirect\/9789240027077<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Cheng Z, Lin P, Cheng N. HBV\/HIV coinfection: impact on the development and clinical treatment of liver diseases. Front Med (Lausanne). 2021;8:713981.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34676223\" aria-label=\"PubMed reference 17\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 17\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HBV%2FHIV%20coinfection%3A%20impact%20on%20the%20development%20and%20clinical%20treatment%20of%20liver%20diseases&amp;journal=Front%20Med%20%28Lausanne%29&amp;volume=8&amp;publication_year=2021&amp;author=Cheng%2CZ&amp;author=Lin%2CP&amp;author=Cheng%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Ngcobo S, Molatlhegi RP, Osman F, Ngcapu S, Samsunder N, Garrett NJ, et al. Pre-infection plasma cytokines and chemokines as predictors of HIV disease progression. Sci Rep. 2022;12(1):2437.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XjsFGnurc%3D\" aria-label=\"CAS reference 18\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35165387\" aria-label=\"PubMed reference 18\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8844050\" aria-label=\"PubMed Central reference 18\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Pre-infection%20plasma%20cytokines%20and%20chemokines%20as%20predictors%20of%20HIV%20disease%20progression&amp;journal=Sci%20Rep&amp;volume=12&amp;issue=1&amp;publication_year=2022&amp;author=Ngcobo%2CS&amp;author=Molatlhegi%2CRP&amp;author=Osman%2CF&amp;author=Ngcapu%2CS&amp;author=Samsunder%2CN&amp;author=Garrett%2CNJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Montanari NR, Anugwom CM, Boonstra A, Debes JD. The Role of Cytokines in the Different Stages of Hepatocellular Carcinoma. Cancers. 2021 ;13(19). Cited 16 Sep 2022. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8508513\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8508513\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8508513\/<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Kany S, Vollrath JT, Relja B. Cytokines in inflammatory disease. Int J Mol Sci. 2019;20(23):6008.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhtFaiu7jK\" aria-label=\"CAS reference 20\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31795299\" aria-label=\"PubMed reference 20\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6929211\" aria-label=\"PubMed Central reference 20\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cytokines%20in%20inflammatory%20disease&amp;journal=Int%20J%20Mol%20Sci&amp;volume=20&amp;issue=23&amp;publication_year=2019&amp;author=Kany%2CS&amp;author=Vollrath%2CJT&amp;author=Relja%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Zamarron BF, Chen W. Dual roles of immune cells and their factors in cancer development and progression. Int J Biol Sci. 2011;7(5):651.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXmsl2lsrg%3D\" aria-label=\"CAS reference 21\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=21647333\" aria-label=\"PubMed reference 21\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3107473\" aria-label=\"PubMed Central reference 21\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 21\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Dual%20roles%20of%20immune%20cells%20and%20their%20factors%20in%20cancer%20development%20and%20progression&amp;journal=Int%20J%20Biol%20Sci&amp;volume=7&amp;issue=5&amp;publication_year=2011&amp;author=Zamarron%2CBF&amp;author=Chen%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Budhu A, Wang XW. The role of cytokines in hepatocellular carcinoma. J Leukoc Biol. 2006;80(6):1197\u2013213.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28XhtlSisLjO\" aria-label=\"CAS reference 22\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16946019\" aria-label=\"PubMed reference 22\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 22\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20role%20of%20cytokines%20in%20hepatocellular%20carcinoma&amp;journal=J%20Leukoc%20Biol&amp;volume=80&amp;issue=6&amp;pages=1197-213&amp;publication_year=2006&amp;author=Budhu%2CA&amp;author=Wang%2CXW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Lan T, Chen L, Wei X. Inflammatory cytokines in cancer: comprehensive Understanding and clinical progress in gene therapy. Cells. 2021;10(1):100.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXhs1equ7zK\" aria-label=\"CAS reference 23\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33429846\" aria-label=\"PubMed reference 23\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7827947\" aria-label=\"PubMed Central reference 23\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Inflammatory%20cytokines%20in%20cancer%3A%20comprehensive%20Understanding%20and%20clinical%20progress%20in%20gene%20therapy&amp;journal=Cells&amp;volume=10&amp;issue=1&amp;publication_year=2021&amp;author=Lan%2CT&amp;author=Chen%2CL&amp;author=Wei%2CX\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Yan B, Wang H, Rabbani ZN, Zhao Y, Li W, Yuan Y, et al. Tumor necrosis Factor-\u03b1 is a potent endogenous mutagen that promotes cellular transformation. Cancer Res. 2006;66(24):11565\u201370.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28XhtlagurvK\" aria-label=\"CAS reference 24\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17178846\" aria-label=\"PubMed reference 24\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Tumor%20necrosis%20Factor-%CE%B1%20is%20a%20potent%20endogenous%20mutagen%20that%20promotes%20cellular%20transformation&amp;journal=Cancer%20Res&amp;volume=66&amp;issue=24&amp;pages=11565-70&amp;publication_year=2006&amp;author=Yan%2CB&amp;author=Wang%2CH&amp;author=Rabbani%2CZN&amp;author=Zhao%2CY&amp;author=Li%2CW&amp;author=Yuan%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">WHO clinical staging of HIV disease in adults, adolescents and children. In: Consolidated Guidelines on the Use of Antiretroviral Drugs for Treating and Preventing HIV Infection: Recommendations for a Public Health Approach 2nd edition. World Health Organization. 2016 Cited 7 Jun 2025. Available from: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK374293\/\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK374293\/\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK374293\/<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Tachi K, Agyei-Nkansah A, Archampong T. Hepatocellular carcinoma in ghana: a retrospective analysis of a tertiary hospital data. Pan Afr Med J. 2020;36:43.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32774619\" aria-label=\"PubMed reference 26\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7388599\" aria-label=\"PubMed Central reference 26\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Hepatocellular%20carcinoma%20in%20ghana%3A%20a%20retrospective%20analysis%20of%20a%20tertiary%20hospital%20data&amp;journal=Pan%20Afr%20Med%20J&amp;volume=36&amp;publication_year=2020&amp;author=Tachi%2CK&amp;author=Agyei-Nkansah%2CA&amp;author=Archampong%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Patridge EF, Bardyn TP. Research electronic data capture (REDCap). J Med Libr Assoc. 2018;106(1):142\u20134.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5764586\" aria-label=\"PubMed Central reference 27\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Research%20electronic%20data%20capture%20%28REDCap%29&amp;journal=J%20Med%20Libr%20Assoc&amp;volume=106&amp;issue=1&amp;pages=142-4&amp;publication_year=2018&amp;author=Patridge%2CEF&amp;author=Bardyn%2CTP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Lu Y, Ahmed S, Harari F, Vahter M. Impact of Ficoll density gradient centrifugation on major and trace element concentrations in erythrocytes and blood plasma. J Trace Elem Med Biol. 2015;29:249\u201354.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXhsVynu7%2FP\" aria-label=\"CAS reference 28\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25240911\" aria-label=\"PubMed reference 28\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 28\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Impact%20of%20Ficoll%20density%20gradient%20centrifugation%20on%20major%20and%20trace%20element%20concentrations%20in%20erythrocytes%20and%20blood%20plasma&amp;journal=J%20Trace%20Elem%20Med%20Biol&amp;volume=29&amp;pages=249-54&amp;publication_year=2015&amp;author=Lu%2CY&amp;author=Ahmed%2CS&amp;author=Harari%2CF&amp;author=Vahter%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Skrzypkowska M, Stasiak M, Sakowska J, Chmiel J, Maciejewska A, Buci\u0144ski A, et al. Cytokines and chemokines multiplex analysis in patients with low disease activity rheumatoid arthritis. Rheumatol Int. 2022;42(4):609\u201319.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XntVSksLw%3D\" aria-label=\"CAS reference 29\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35179632\" aria-label=\"PubMed reference 29\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8940835\" aria-label=\"PubMed Central reference 29\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cytokines%20and%20chemokines%20multiplex%20analysis%20in%20patients%20with%20low%20disease%20activity%20rheumatoid%20arthritis&amp;journal=Rheumatol%20Int&amp;volume=42&amp;issue=4&amp;pages=609-19&amp;publication_year=2022&amp;author=Skrzypkowska%2CM&amp;author=Stasiak%2CM&amp;author=Sakowska%2CJ&amp;author=Chmiel%2CJ&amp;author=Maciejewska%2CA&amp;author=Buci%C5%84ski%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Aztatzi-Aguilar OG, Sierra-Vargas MP, Ortega-Romero M, Jim\u00e9nez-Corona AE. Osteopontin\u2019s relationship with malnutrition and oxidative stress in adolescents. A pilot study. PLoS ONE. 2021;16(3):e0249057.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXnsl2qtLo%3D\" aria-label=\"CAS reference 30\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33765028\" aria-label=\"PubMed reference 30\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7993823\" aria-label=\"PubMed Central reference 30\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Osteopontin%E2%80%99s%20relationship%20with%20malnutrition%20and%20oxidative%20stress%20in%20adolescents.%20A%20pilot%20study&amp;journal=PLoS%20ONE&amp;volume=16&amp;issue=3&amp;publication_year=2021&amp;author=Aztatzi-Aguilar%2COG&amp;author=Sierra-Vargas%2CMP&amp;author=Ortega-Romero%2CM&amp;author=Jim%C3%A9nez-Corona%2CAE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Chen T, He J, Shen L, Fang H, Nie H, Jin T, et al. The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer. BMC Med Genet. 2011;12:8.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXht1KltbY%3D\" aria-label=\"CAS reference 31\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=21232124\" aria-label=\"PubMed reference 31\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3025938\" aria-label=\"PubMed Central reference 31\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20mitochondrial%20DNA%204%2C977-bp%20deletion%20and%20its%20implication%20in%20copy%20number%20alteration%20in%20colorectal%20cancer&amp;journal=BMC%20Med%20Genet&amp;volume=12&amp;publication_year=2011&amp;author=Chen%2CT&amp;author=He%2CJ&amp;author=Shen%2CL&amp;author=Fang%2CH&amp;author=Nie%2CH&amp;author=Jin%2CT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">Srinivasan S, Guha M, Kashina A, Avadhani NG. Mitochondrial dysfunction and mitochondrial Dynamics-The cancer connection. Biochim Biophys Acta. 2017;1858(8):602\u201314.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2sXhs1Khs78%3D\" aria-label=\"CAS reference 32\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5487289\" aria-label=\"PubMed Central reference 32\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mitochondrial%20dysfunction%20and%20mitochondrial%20Dynamics-The%20cancer%20connection&amp;journal=Biochim%20Biophys%20Acta&amp;volume=1858&amp;issue=8&amp;pages=602-14&amp;publication_year=2017&amp;author=Srinivasan%2CS&amp;author=Guha%2CM&amp;author=Kashina%2CA&amp;author=Avadhani%2CNG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Kowald A, Kirkwood TBL. Transcription could be the key to the selection advantage of mitochondrial deletion mutants in aging. Proceedings of the National Academy of Sciences. 2014;111(8):2972\u20137.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Borges \u00c1H, Silverberg MJ, Wentworth D, Grulich AE, F\u00e4tkenheuer G, Mitsuyasu R, et al. Predicting risk of cancer during HIV infection: the role of inflammatory and coagulation biomarkers. AIDS. 2013;27(9):1433\u201341.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXpsFais7o%3D\" aria-label=\"CAS reference 34\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23945504\" aria-label=\"PubMed reference 34\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Predicting%20risk%20of%20cancer%20during%20HIV%20infection%3A%20the%20role%20of%20inflammatory%20and%20coagulation%20biomarkers&amp;journal=AIDS&amp;volume=27&amp;issue=9&amp;pages=1433-41&amp;publication_year=2013&amp;author=Borges%2C%C3%81H&amp;author=Silverberg%2CMJ&amp;author=Wentworth%2CD&amp;author=Grulich%2CAE&amp;author=F%C3%A4tkenheuer%2CG&amp;author=Mitsuyasu%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Chen X, Liu X, Duan S, Tang R, Zhou S, Ye R, et al. Plasma inflammatory biomarkers associated with advanced liver fibrosis in HIV\u2013HCV-Coinfected individuals. Int J Environ Res Public Health. 2020;17(24):9474.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXitlyks70%3D\" aria-label=\"CAS reference 35\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33348839\" aria-label=\"PubMed reference 35\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7766690\" aria-label=\"PubMed Central reference 35\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Plasma%20inflammatory%20biomarkers%20associated%20with%20advanced%20liver%20fibrosis%20in%20HIV%E2%80%93HCV-Coinfected%20individuals&amp;journal=Int%20J%20Environ%20Res%20Public%20Health&amp;volume=17&amp;issue=24&amp;publication_year=2020&amp;author=Chen%2CX&amp;author=Liu%2CX&amp;author=Duan%2CS&amp;author=Tang%2CR&amp;author=Zhou%2CS&amp;author=Ye%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Hu S, Ghabril M, Amet T, Hu N, Byrd D, Yang K, et al. HIV-1 coinfection profoundly alters intrahepatic chemokine but not inflammatory cytokine profiles in HCV-Infected subjects. PLoS ONE. 2014;9(2):e86964.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=24516541\" aria-label=\"PubMed reference 36\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3916319\" aria-label=\"PubMed Central reference 36\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HIV-1%20coinfection%20profoundly%20alters%20intrahepatic%20chemokine%20but%20not%20inflammatory%20cytokine%20profiles%20in%20HCV-Infected%20subjects&amp;journal=PLoS%20ONE&amp;volume=9&amp;issue=2&amp;publication_year=2014&amp;author=Hu%2CS&amp;author=Ghabril%2CM&amp;author=Amet%2CT&amp;author=Hu%2CN&amp;author=Byrd%2CD&amp;author=Yang%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Shata MTM, Abdel-hameed EA, Rouster SD, Yu L, Liang M, Song E, et al. HBV and HIV\/HBV infected patients have distinct immune exhaustion and apoptotic serum biomarker profiles. Pathogens Immun. 2019;4(1):39\u201365.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HBV%20and%20HIV%2FHBV%20infected%20patients%20have%20distinct%20immune%20exhaustion%20and%20apoptotic%20serum%20biomarker%20profiles&amp;journal=Pathogens%20Immun&amp;volume=4&amp;issue=1&amp;pages=39-65&amp;publication_year=2019&amp;author=Shata%2CMTM&amp;author=Abdel-hameed%2CEA&amp;author=Rouster%2CSD&amp;author=Yu%2CL&amp;author=Liang%2CM&amp;author=Song%2CE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">Falasca K, Ucciferri C, Dalessandro M, Zingariello P, Mancino P, Petrarca C, et al. Cytokine patterns correlate with liver damage in patients with chronic hepatitis B and C. Ann Clin Lab Sci. 2006;36(2):144\u201350.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28XlvVSlsrs%3D\" aria-label=\"CAS reference 38\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16682509\" aria-label=\"PubMed reference 38\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cytokine%20patterns%20correlate%20with%20liver%20damage%20in%20patients%20with%20chronic%20hepatitis%20B%20and%20C&amp;journal=Ann%20Clin%20Lab%20Sci&amp;volume=36&amp;issue=2&amp;pages=144-50&amp;publication_year=2006&amp;author=Falasca%2CK&amp;author=Ucciferri%2CC&amp;author=Dalessandro%2CM&amp;author=Zingariello%2CP&amp;author=Mancino%2CP&amp;author=Petrarca%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">Gupta D, Rani M, Khan N, Jameel S. HIV-1 infected peripheral blood mononuclear cells modulate the fibrogenic activity of hepatic stellate cells through secreted TGF-\u03b2 and JNK signaling. PLoS ONE. 2014;9(3):e91569.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=24637780\" aria-label=\"PubMed reference 39\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3956633\" aria-label=\"PubMed Central reference 39\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HIV-1%20infected%20peripheral%20blood%20mononuclear%20cells%20modulate%20the%20fibrogenic%20activity%20of%20hepatic%20stellate%20cells%20through%20secreted%20TGF-%CE%B2%20and%20JNK%20signaling&amp;journal=PLoS%20ONE&amp;volume=9&amp;issue=3&amp;publication_year=2014&amp;author=Gupta%2CD&amp;author=Rani%2CM&amp;author=Khan%2CN&amp;author=Jameel%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Ribeiro CR, de Beghini A, Lemos DG, Martinelli AS, de Mello KG, da Almeida V. Cytokines profile in patients with acute and chronic hepatitis B infection. Microbiol Immunol. 2022;66(1):31\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXis1Wit7%2FI\" aria-label=\"CAS reference 40\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34647645\" aria-label=\"PubMed reference 40\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 40\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cytokines%20profile%20in%20patients%20with%20acute%20and%20chronic%20hepatitis%20B%20infection&amp;journal=Microbiol%20Immunol&amp;volume=66&amp;issue=1&amp;pages=31-9&amp;publication_year=2022&amp;author=Ribeiro%2CCR&amp;author=Beghini%2CA&amp;author=Lemos%2CDG&amp;author=Martinelli%2CAS&amp;author=Mello%2CKG&amp;author=Almeida%2CV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Zajkowska M, Mroczko B. Chemokines in primary liver cancer. Int J Mol Sci. 2022;23(16):8846.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38Xit1ykurnL\" aria-label=\"CAS reference 41\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36012108\" aria-label=\"PubMed reference 41\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9408270\" aria-label=\"PubMed Central reference 41\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Chemokines%20in%20primary%20liver%20cancer&amp;journal=Int%20J%20Mol%20Sci&amp;volume=23&amp;issue=16&amp;publication_year=2022&amp;author=Zajkowska%2CM&amp;author=Mroczko%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">da Cruz NS, Pasquarelli-do-Nascimento G, e Oliveira ACP, Magalh\u00e3es KG. Inflammasome-Mediated cytokines: A key connection between Obesity-Associated NASH and liver cancer progression. Biomedicines. 2022;10(10):2344.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36289606\" aria-label=\"PubMed reference 42\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9598450\" aria-label=\"PubMed Central reference 42\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Inflammasome-Mediated%20cytokines%3A%20A%20key%20connection%20between%20Obesity-Associated%20NASH%20and%20liver%20cancer%20progression&amp;journal=Biomedicines&amp;volume=10&amp;issue=10&amp;publication_year=2022&amp;author=Cruz%2CNS&amp;author=Pasquarelli-do-Nascimento%2CG&amp;author=e%20Oliveira%2CACP&amp;author=Magalh%C3%A3es%2CKG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Naseem S, Hussain T, Manzoor S. Interleukin-6: A promising cytokine to support liver regeneration and adaptive immunity in liver pathologies. Cytokine Growth Factor Rev. 2018;39:36\u201345.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXhtlOjtrs%3D\" aria-label=\"CAS reference 43\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29361380\" aria-label=\"PubMed reference 43\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Interleukin-6%3A%20A%20promising%20cytokine%20to%20support%20liver%20regeneration%20and%20adaptive%20immunity%20in%20liver%20pathologies&amp;journal=Cytokine%20Growth%20Factor%20Rev&amp;volume=39&amp;pages=36-45&amp;publication_year=2018&amp;author=Naseem%2CS&amp;author=Hussain%2CT&amp;author=Manzoor%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">You R, Jiang H, Xu Q, Yin G. Preintervention MCP-1 serum levels as an early predictive marker of tumor response in patients with hepatocellular carcinoma undergoing transarterial chemoembolization. Transl Cancer Res. 2021;10(2):966\u201376.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXnvV2hs7s%3D\" aria-label=\"CAS reference 44\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35116424\" aria-label=\"PubMed reference 44\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8797576\" aria-label=\"PubMed Central reference 44\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Preintervention%20MCP-1%20serum%20levels%20as%20an%20early%20predictive%20marker%20of%20tumor%20response%20in%20patients%20with%20hepatocellular%20carcinoma%20undergoing%20transarterial%20chemoembolization&amp;journal=Transl%20Cancer%20Res&amp;volume=10&amp;issue=2&amp;pages=966-76&amp;publication_year=2021&amp;author=You%2CR&amp;author=Jiang%2CH&amp;author=Xu%2CQ&amp;author=Yin%2CG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">He Y, Ye M, Xia Y, Zhong Z, Wang W, Li Q. The role of cytokines as predictors for NAFLD-related diseases: A bidirectional Mendelian randomization study. Clin Res Hepatol Gastroenterol. 2025;49(3):102545.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB2MXjtFWrsb8%3D\" aria-label=\"CAS reference 45\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39900199\" aria-label=\"PubMed reference 45\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 45\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20role%20of%20cytokines%20as%20predictors%20for%20NAFLD-related%20diseases%3A%20A%20bidirectional%20Mendelian%20randomization%20study&amp;journal=Clin%20Res%20Hepatol%20Gastroenterol&amp;volume=49&amp;issue=3&amp;publication_year=2025&amp;author=He%2CY&amp;author=Ye%2CM&amp;author=Xia%2CY&amp;author=Zhong%2CZ&amp;author=Wang%2CW&amp;author=Li%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">Park EJ, Lee JH, Yu GY, He G, Ali SR, Holzer RG, et al. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression. Cell. 2010;140(2):197\u2013208.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3cXkvVWitLw%3D\" aria-label=\"CAS reference 46\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=20141834\" aria-label=\"PubMed reference 46\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2836922\" aria-label=\"PubMed Central reference 46\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 46\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Dietary%20and%20genetic%20obesity%20promote%20liver%20inflammation%20and%20tumorigenesis%20by%20enhancing%20IL-6%20and%20TNF%20expression&amp;journal=Cell&amp;volume=140&amp;issue=2&amp;pages=197-208&amp;publication_year=2010&amp;author=Park%2CEJ&amp;author=Lee%2CJH&amp;author=Yu%2CGY&amp;author=He%2CG&amp;author=Ali%2CSR&amp;author=Holzer%2CRG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">El-Mikkawy DME, EL-Sadek MA, EL-Badawy MA, Samaha D. Circulating level of interleukin-6 in relation to body mass indices and lipid profile in Egyptian adults with overweight and obesity. Egypt Rheumatol Rehabilitation. 2020;47(1):7.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Circulating%20level%20of%20interleukin-6%20in%20relation%20to%20body%20mass%20indices%20and%20lipid%20profile%20in%20Egyptian%20adults%20with%20overweight%20and%20obesity&amp;journal=Egypt%20Rheumatol%20Rehabilitation&amp;volume=47&amp;issue=1&amp;publication_year=2020&amp;author=El-Mikkawy%2CDME&amp;author=EL-Sadek%2CMA&amp;author=EL-Badawy%2CMA&amp;author=Samaha%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Matsui D, Nagai H, Mukozu T, Ogino Y, Sumino Y. VEGF in patients with advanced hepatocellular carcinoma receiving Intra-arterial chemotherapy. Anticancer Res. 2015;35(4):2205\u201310.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXotVaju7k%3D\" aria-label=\"CAS reference 48\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25862879\" aria-label=\"PubMed reference 48\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=VEGF%20in%20patients%20with%20advanced%20hepatocellular%20carcinoma%20receiving%20Intra-arterial%20chemotherapy&amp;journal=Anticancer%20Res&amp;volume=35&amp;issue=4&amp;pages=2205-10&amp;publication_year=2015&amp;author=Matsui%2CD&amp;author=Nagai%2CH&amp;author=Mukozu%2CT&amp;author=Ogino%2CY&amp;author=Sumino%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">Sadeghi M, Lahdou I, Oweira H, Daniel V, Terness P, Schmidt J, et al. Serum levels of chemokines CCL4 and CCL5 in cirrhotic patients indicate the presence of hepatocellular carcinoma. Br J Cancer. 2015;113(5):756\u201362.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXhtlOhtLfP\" aria-label=\"CAS reference 49\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26270232\" aria-label=\"PubMed reference 49\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4559820\" aria-label=\"PubMed Central reference 49\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 49\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Serum%20levels%20of%20chemokines%20CCL4%20and%20CCL5%20in%20cirrhotic%20patients%20indicate%20the%20presence%20of%20hepatocellular%20carcinoma&amp;journal=Br%20J%20Cancer&amp;volume=113&amp;issue=5&amp;pages=756-62&amp;publication_year=2015&amp;author=Sadeghi%2CM&amp;author=Lahdou%2CI&amp;author=Oweira%2CH&amp;author=Daniel%2CV&amp;author=Terness%2CP&amp;author=Schmidt%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Choi SB, Han HJ, Kim WB, Song TJ, Choi SY. VEGF overexpression predicts poor survival in hepatocellular carcinoma. Open Med. 2017;12(1):430\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXmtFSltr4%3D\" aria-label=\"CAS reference 50\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=VEGF%20overexpression%20predicts%20poor%20survival%20in%20hepatocellular%20carcinoma&amp;journal=Open%20Med&amp;volume=12&amp;issue=1&amp;pages=430-9&amp;publication_year=2017&amp;author=Choi%2CSB&amp;author=Han%2CHJ&amp;author=Kim%2CWB&amp;author=Song%2CTJ&amp;author=Choi%2CSY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">Dong G, Fan F, He Y, Luo Y, Yu J, Liang P. T-Lymphocyte Gene-Regulated CCL5 and its association with extrahepatic metastasis in hepatocellular carcinoma. JHC. 2023;10:1267\u201379.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXhs12mt73P\" aria-label=\"CAS reference 51\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=T-Lymphocyte%20Gene-Regulated%20CCL5%20and%20its%20association%20with%20extrahepatic%20metastasis%20in%20hepatocellular%20carcinoma&amp;journal=JHC&amp;volume=10&amp;pages=1267-79&amp;publication_year=2023&amp;author=Dong%2CG&amp;author=Fan%2CF&amp;author=He%2CY&amp;author=Luo%2CY&amp;author=Yu%2CJ&amp;author=Liang%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Soliman HH, Nagy H, Kotb N, El-Din MAA. The role of chemokine CC ligand 20 in patients with liver cirrhosis and hepatocellular carcinoma. Int J Biol Markers. 2012;27(2):125\u201331.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXht1ShsL0%3D\" aria-label=\"CAS reference 52\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 52\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20role%20of%20chemokine%20CC%20ligand%2020%20in%20patients%20with%20liver%20cirrhosis%20and%20hepatocellular%20carcinoma&amp;journal=Int%20J%20Biol%20Markers&amp;volume=27&amp;issue=2&amp;pages=125-31&amp;publication_year=2012&amp;author=Soliman%2CHH&amp;author=Nagy%2CH&amp;author=Kotb%2CN&amp;author=El-Din%2CMAA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Beckebaum S, Zhang X, Chen X, Yu Z, Frilling A, Dworacki G, et al. Increased levels of Interleukin-10 in serum from patients with hepatocellular carcinoma correlate with profound numerical deficiencies and immature phenotype of Circulating dendritic cell subsets. Clin Cancer Res. 2004;10(21):7260\u20139.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2cXpsVKlur4%3D\" aria-label=\"CAS reference 53\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=15534100\" aria-label=\"PubMed reference 53\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Increased%20levels%20of%20Interleukin-10%20in%20serum%20from%20patients%20with%20hepatocellular%20carcinoma%20correlate%20with%20profound%20numerical%20deficiencies%20and%20immature%20phenotype%20of%20Circulating%20dendritic%20cell%20subsets&amp;journal=Clin%20Cancer%20Res&amp;volume=10&amp;issue=21&amp;pages=7260-9&amp;publication_year=2004&amp;author=Beckebaum%2CS&amp;author=Zhang%2CX&amp;author=Chen%2CX&amp;author=Yu%2CZ&amp;author=Frilling%2CA&amp;author=Dworacki%2CG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Qian Q, Wu C, Chen J, Wang W. Relationship between IL10 and PD-L1 in liver hepatocellular carcinoma tissue and cell lines. Biomed Res Int. 2020;2020:e8910183.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Relationship%20between%20IL10%20and%20PD-L1%20in%20liver%20hepatocellular%20carcinoma%20tissue%20and%20cell%20lines&amp;journal=Biomed%20Res%20Int&amp;volume=2020&amp;publication_year=2020&amp;author=Qian%2CQ&amp;author=Wu%2CC&amp;author=Chen%2CJ&amp;author=Wang%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Rubie C, Frick VO, Wagner M, Rau B, Weber C, Kruse B, et al. Enhanced expression and clinical significance of CC-Chemokine MIP-3\u03b1 in hepatocellular carcinoma. Scand J Immunol. 2006;63(6):468\u201377.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28XntF2lsLY%3D\" aria-label=\"CAS reference 55\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16764701\" aria-label=\"PubMed reference 55\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Enhanced%20expression%20and%20clinical%20significance%20of%20CC-Chemokine%20MIP-3%CE%B1%20in%20hepatocellular%20carcinoma&amp;journal=Scand%20J%20Immunol&amp;volume=63&amp;issue=6&amp;pages=468-77&amp;publication_year=2006&amp;author=Rubie%2CC&amp;author=Frick%2CVO&amp;author=Wagner%2CM&amp;author=Rau%2CB&amp;author=Weber%2CC&amp;author=Kruse%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Zhang S, Gan X, Qiu J, Ju Z, Gao J, Zhou J, et al. IL-10 derived from hepatocarcinoma cells improves human induced regulatory T cells function via JAK1\/STAT5 pathway in tumor microenvironment. Mol Immunol. 2021;133:163\u201372.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXlsFSmtrc%3D\" aria-label=\"CAS reference 56\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33667986\" aria-label=\"PubMed reference 56\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 56\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=IL-10%20derived%20from%20hepatocarcinoma%20cells%20improves%20human%20induced%20regulatory%20T%20cells%20function%20via%20JAK1%2FSTAT5%20pathway%20in%20tumor%20microenvironment&amp;journal=Mol%20Immunol&amp;volume=133&amp;pages=163-72&amp;publication_year=2021&amp;author=Zhang%2CS&amp;author=Gan%2CX&amp;author=Qiu%2CJ&amp;author=Ju%2CZ&amp;author=Gao%2CJ&amp;author=Zhou%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Ji X, Guo W, Gu X, Guo S, Zhou K, Su L et al. Mutational profiling of mtDNA control region reveals tumor-specific evolutionary selection involved in mitochondrial dysfunction. eBioMedicine. 2022 ;80. Cited 19 Aug 2023. Available from: <a href=\"https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(22)00239-0\/fulltext\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(22)00239-0\/fulltext\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/www.thelancet.com\/journals\/ebiom\/article\/PIIS2352-3964(22)00239-0\/fulltext<\/a>.<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Li M, Foli Y, Liu Z, Wang G, Hu Y, Lu Q, et al. High frequency of mitochondrial DNA mutations in HIV-infected treatment\u2010experienced individuals. HIV Med. 2017;18(1):45\u201355.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC28XhvFyku7jI\" aria-label=\"CAS reference 58\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27328746\" aria-label=\"PubMed reference 58\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=High%20frequency%20of%20mitochondrial%20DNA%20mutations%20in%20HIV-infected%20treatment%E2%80%90experienced%20individuals&amp;journal=HIV%20Med&amp;volume=18&amp;issue=1&amp;pages=45-55&amp;publication_year=2017&amp;author=Li%2CM&amp;author=Foli%2CY&amp;author=Liu%2CZ&amp;author=Wang%2CG&amp;author=Hu%2CY&amp;author=Lu%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR59\">de Mendoza C, S\u00e1nchez-Conde M, Timmermans E, Buitelaar M, de Baar MP, Gonzalez-Lahoz J, et al. Mitochondrial Dna depletion in HIV-Infected patients is more pronounced with chronic hepatitis C and enhanced following treatment with pegylated interferon plus ribavirin. Antivir Ther. 2005;10(4):557\u201361.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16038482\" aria-label=\"PubMed reference 59\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 59\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mitochondrial%20Dna%20depletion%20in%20HIV-Infected%20patients%20is%20more%20pronounced%20with%20chronic%20hepatitis%20C%20and%20enhanced%20following%20treatment%20with%20pegylated%20interferon%20plus%20ribavirin&amp;journal=Antivir%20Ther&amp;volume=10&amp;issue=4&amp;pages=557-61&amp;publication_year=2005&amp;author=Mendoza%2CC&amp;author=S%C3%A1nchez-Conde%2CM&amp;author=Timmermans%2CE&amp;author=Buitelaar%2CM&amp;author=Baar%2CMP&amp;author=Gonzalez-Lahoz%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR60\">Yu C, Wang X, Huang L, Tong Y, Chen L, Wu H, et al. Deciphering the spectrum of mitochondrial DNA mutations in hepatocellular carcinoma using High-Throughput sequencing. Gene Expr. 2018;18(2):125\u201334.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhvVGiurvI\" aria-label=\"CAS reference 60\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29463347\" aria-label=\"PubMed reference 60\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5954625\" aria-label=\"PubMed Central reference 60\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Deciphering%20the%20spectrum%20of%20mitochondrial%20DNA%20mutations%20in%20hepatocellular%20carcinoma%20using%20High-Throughput%20sequencing&amp;journal=Gene%20Expr&amp;volume=18&amp;issue=2&amp;pages=125-34&amp;publication_year=2018&amp;author=Yu%2CC&amp;author=Wang%2CX&amp;author=Huang%2CL&amp;author=Tong%2CY&amp;author=Chen%2CL&amp;author=Wu%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR61\">Vadrot N, Ghanem S, Braut F, Gavrilescu L, Pilard N, Mansouri A, et al. Mitochondrial DNA maintenance is regulated in human hepatoma cells by glycogen synthase kinase 3\u03b2 and p53 in response to tumor necrosis factor \u03b1. PLoS ONE. 2012;7(7):e40879.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC38XhtFSkt7vE\" aria-label=\"CAS reference 61\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=22911714\" aria-label=\"PubMed reference 61\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3401193\" aria-label=\"PubMed Central reference 61\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 61\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mitochondrial%20DNA%20maintenance%20is%20regulated%20in%20human%20hepatoma%20cells%20by%20glycogen%20synthase%20kinase%203%CE%B2%20and%20p53%20in%20response%20to%20tumor%20necrosis%20factor%20%CE%B1&amp;journal=PLoS%20ONE&amp;volume=7&amp;issue=7&amp;publication_year=2012&amp;author=Vadrot%2CN&amp;author=Ghanem%2CS&amp;author=Braut%2CF&amp;author=Gavrilescu%2CL&amp;author=Pilard%2CN&amp;author=Mansouri%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Giampazolias E, Tait SWG. Mitochondria and the hallmarks of cancer. FEBS J. 2016;283(5):803\u201314.<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/bmcgastroenterol.biomedcentral.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXitVylur%2FO\" aria-label=\"CAS reference 62\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26607558\" aria-label=\"PubMed reference 62\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mitochondria%20and%20the%20hallmarks%20of%20cancer&amp;journal=FEBS%20J&amp;volume=283&amp;issue=5&amp;pages=803-14&amp;publication_year=2016&amp;author=Giampazolias%2CE&amp;author=Tait%2CSWG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n","protected":false},"excerpt":{"rendered":"Bower M, Palmieri C, Stebbing J. AIDS associated malignancies. Update Cancer Ther. 2006;1(2):221\u201334. Google Scholar\u00a0 Franceschi S, Lise&hellip;\n","protected":false},"author":2,"featured_media":134298,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[1707,103,14788,78163,32688,78164,61,78165,1704,60,78166],"class_list":{"0":"post-134297","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-gastroenterology","9":"tag-health","10":"tag-hepatitis","11":"tag-hepatocellular-carcinoma-hcc","12":"tag-hepatology","13":"tag-human-immunodeficiency-virus-hiv","14":"tag-ie","15":"tag-inflammatory-cytokines","16":"tag-internal-medicine","17":"tag-ireland","18":"tag-mitochondrial-dna-deletion"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/134297","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=134297"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/134297\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/134298"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=134297"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=134297"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=134297"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}