{"id":151479,"date":"2025-11-21T06:34:09","date_gmt":"2025-11-21T06:34:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/151479\/"},"modified":"2025-11-21T06:34:09","modified_gmt":"2025-11-21T06:34:09","slug":"unmasking-pandemic-patterns-decoding-the-covid-19s-impact-on-mortality-in-italy-with-generalized-gamma-overdispersion-model-bmc-public-health","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/151479\/","title":{"rendered":"Unmasking pandemic patterns: decoding the COVID-19\u2019s impact on mortality in Italy with Generalized Gamma overdispersion model | BMC Public Health"},"content":{"rendered":"

Remuzzi A, Remuzzi G. COVID-19 and italy: what next? Lancet. 2020;395:1225\u20138. https:\/\/doi.org\/10.1016\/S0140-6736(20)30627-9<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Indolfi C, Spaccarotella C. The outbreak of COVID-19 in Italy. JACC: Case Rep. 2020;2:1414\u20138. https:\/\/doi.org\/10.1016\/j.jaccas.2020.03.012<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Wang H, Paulson KR, Pease SA, Watson S, Comfort H, Zheng P, Aravkin AY, Bisignano C, Barber RM, Alam T, et al. Estimating excess mortality due to the COVID-19 pandemic: A systematic analysis of COVID-19-Related mortality, 2020\u201321. Lancet. 2022;399:1513\u201336. https:\/\/doi.org\/10.1016\/S0140-6736(21)02796-3<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Michelozzi P, de\u2019Donato F, Scortichini M, Pezzotti P, Stafoggia M, De Sario M, Costa G, Noccioli F, Riccardo F, Bella A, et al. Temporal dynamics in total excess mortality and COVID-19 deaths in Italian cities. BMC Public Health. 2020;20:1238. https:\/\/doi.org\/10.1186\/s12889-020-09335-8<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Magnani C, Azzolina D, Gallo E, Ferrante D, Gregori D. How large was the mortality increase directly and indirectly caused by the COVID-19 epidemic? An analysis on All-Causes mortality data in Italy. Int J Environ Res Public Health. 2020;17. https:\/\/doi.org\/10.3390\/ijerph17103452<\/a>.<\/p>\n

Kontis V, Bennett JE, Rashid T, Parks RM, Pearson-Stuttard J, Guillot M, Asaria P, Zhou B, Battaglini M, Corsetti G, et al. Magnitude, demographics and dynamics of the effect of the first wave of the COVID-19 pandemic on All-Cause mortality in 21 industrialized countries. Nat Med. 2020;26:1919\u201328. https:\/\/doi.org\/10.1038\/s41591-020-1112-0<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Onder G, Rezza G, Brusaferro S. Case-Fatality rate and characteristics of patients dying in relation to COVID-19 in Italy. JAMA. 2020. https:\/\/doi.org\/10.1001\/jama.2020.4683<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Azzolina D, Magnani C, Gallo E, Ferrante D, Gregori D. Gender and age factors affecting the mortality during the COVID-19 epidemic in Italy. Epidemiol Prev. 2020;44:252\u20139. https:\/\/doi.org\/10.19191\/EP20.5-6.S2.125<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Dorrucci M, Minelli G, Boros S, Manno V, Prati S, Battaglini M, Corsetti G, Andrianou X, Riccardo F, Fabiani M, et al. Excess mortality in Italy during the COVID-19 pandemic: assessing the differences between the first and the second Wave, year 2020. Front Public Health. 2021;9:669209. https:\/\/doi.org\/10.3389\/fpubh.2021.669209<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Konstantinoudis G, Cameletti M, G\u00f3mez-Rubio V, G\u00f3mez IL, Pirani M, Baio G, Larrauri A, Riou J, Egger M, Vineis P, et al. Regional excess mortality during the 2020 COVID-19 pandemic in five European countries. Nat Commun. 2022;13:482. https:\/\/doi.org\/10.1038\/s41467-022-28157-3<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

ISTAT Mortality Data Tables Https:\/\/Www.Istat.It\/It\/Archivio\/240401<\/a>. Last Accessed on May 4rd 2020.<\/p>\n

ISTAT Demography in. Figures Http:\/\/Demo.Istat.It<\/a>\/ Last Accessed on June 3rd 2022.<\/p>\n

Italian Civil Protection Http:\/\/Www.Protezionecivile.It\/Web\/Guest\/homePro<\/a>. 2020.<\/p>\n

Lanera C, Azzolina D, Pirotti F, Prosepe I, Lorenzoni G, Berchialla P, Gregori D. A Web-Based application to monitor and inform about the COVID-19 outbreak in italy: the {COVID-19ita} initiative. Healthcare. 2022;10(473). https:\/\/doi.org\/10.3390\/healthcare10030473<\/a>.<\/p>\n

Msemburi W, Karlinsky A, Knutson V, Aleshin-Guendel S, Chatterji S, Wakefield J. The WHO estimates of excess mortality associated with the COVID-19 pandemic. Nature. 2023;613:130\u20137. https:\/\/doi.org\/10.1038\/s41586-022-05522-2<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Rigby RA, Stasinopoulos DM. Generalized additive models for Location, scale and shape. J Royal Stat Soc Ser C: Appl Stat. 2005;54:507\u201354. https:\/\/doi.org\/10.1111\/j.1467-9876.2005.00510.x<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Cox C, Matheson MA. Comparison of the generalized gamma and exponentiated Weibull distributions. Stat Med. 2014;33:3772\u201380. https:\/\/doi.org\/10.1002\/sim.6159<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Core Team R. R: A Language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2022.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Flexible Regression and Smoothing: Using GAMLSS in R; Stasinopoulos, M.D., Ed.; CRC Press\/Taylor & Francis Group: Boca Raton, 2017; ISBN 978-1-138-19790-9.<\/p>\n

Huang G, Guo F, Liu L, Taksa L, Cheng Z, Tani M, Zimmermann KF, Franklin M, Silva SS. M. Changing impact of COVID-19 on life expectancy 2019\u20132023 and its decomposition: findings from 27 countries. SSM – Popul Health. 2024;25:101568. https:\/\/doi.org\/10.1016\/j.ssmph.2023.101568<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Haldane V, De Foo C, Abdalla SM, Jung A-S, Tan M, Wu S, Chua A, Verma M, Shrestha P, Singh S, et al. Health systems resilience in managing the COVID-19 pandemic: lessons from 28 countries. Nat Med. 2021;27:964\u201380. https:\/\/doi.org\/10.1038\/s41591-021-01381-y<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Alicandro G, Remuzzi G, Centanni S, Gerli A, La Vecchia C. Excess total mortality during the Covid-19 pandemic in italy: updated estimates indicate persistent excess in recent months. La Med Del Lavoro | Work Environ Health. 2022;113:e2022021. https:\/\/doi.org\/10.23749\/mdl.v113i2.13108<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Leon DA, Shkolnikov VM, Smeeth L, Magnus P, Pechholdov\u00e1 M, Jarvis CI. COVID-19: A need for Real-Time monitoring of weekly excess deaths. Lancet. 2020;395:e81. https:\/\/doi.org\/10.1016\/S0140-6736(20)30933-8<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Reno C, Sanmarchi F, Stoto MA, Fantini MP, Lenzi J, Golinelli D. The impact of health policies and vaccine rollout on the COVID-19 pandemic waves in Italy. Health Policy Technol. 2022;11:100604. https:\/\/doi.org\/10.1016\/j.hlpt.2022.100604<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Filip R, Gheorghita Puscaselu R, Anchidin-Norocel L, Dimian M, Savage WK. Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems. JPM.\u00a02022;12:1295. https:\/\/doi.org\/10.3390\/jpm12081295<\/a>.<\/p>\n

Pirrotta L, Guidotti E, Tramontani C, Bignardelli E, Venturi G, De Rosis S. COVID-19 vaccinations: an overview of the Italian National health system\u2019s online communication from a citizen perspective. Health Policy. 2022;126:970\u20139. https:\/\/doi.org\/10.1016\/j.healthpol.2022.08.001<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Lamberti-Castronuovo A, Parotto E, Della Corte F, Hubloue I, Ragazzoni L, Valente M. The COVID-19 pandemic response and its impact on Post-Corona health emergency and disaster risk management in Italy. Front Public Health. 2022;10:1034196. https:\/\/doi.org\/10.3389\/fpubh.2022.1034196<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Zamagni G, Armocida B, Abbafati C, Ronfani L, Monasta L. COVID-19 vaccination coverage in italy: how many hospitalisations and related costs could have been saved if we were all vaccinated? Front Public Health. 2022;10:825416. https:\/\/doi.org\/10.3389\/fpubh.2022.825416<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Bezzini D, Schiavetti I, Manacorda T, Franzone G, Battaglia MA. First Wave of COVID-19 Pandemic in Italy: Data and Evidence. In Coronavirus Therapeutics \u2013 Volume II; Asea, A.A.A., Kaur, P., Eds.; Advances in Experimental Medicine and Biology; Springer International Publishing: Cham, 2021;1353:91\u2013113. ISBN 978-3-030-85112-5.<\/p>\n

Gallo E, Prosepe I, Lorenzoni G, Acar A\u015e, Lanera C, Berchialla P, Azzolina D, Gregori D. Excess of All-Cause mortality is only partially explained by COVID-19 in Veneto (Italy) during spring outbreak. BMC Public Health. 2021;21. https:\/\/doi.org\/10.1186\/s12889-021-10832-7<\/a>.<\/p>\n

Gregori D, Azzolina D, Lanera C, Prosepe I, Destro N, Lorenzoni G, Berchialla PA. First Estimation of the impact of public health actions against COVID-19 in Veneto (Italy). J Epidemiol Commun Health. 2020;74:858\u201360. https:\/\/doi.org\/10.1136\/jech-2020-214209<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Azzolina D, Lorenzoni G, Silvestri L, Prosepe I, Berchialla P, Gregori D. Regional differences in mortality rates during the COVID-19 epidemic in Italy. Disaster Med Pub Health Prep. 2020;1\u201322. https:\/\/doi.org\/10.1017\/dmp.2020.486<\/a>.<\/p>\n

Pearson-Stuttard J, Caul S, McDonald S, Whamond E, Newton JN. Excess mortality in England post Covid-19 pandemic: implications for secondary prevention. Lancet Reg Health – Europe. 2024;36:100802. https:\/\/doi.org\/10.1016\/j.lanepe.2023.100802<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Mueller AL, McNamara MS, Sinclair DA. Why does COVID-19 disproportionately affect older people? Aging. 2020;12:9959\u201381. https:\/\/doi.org\/10.18632\/aging.103344<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Panovska-Griffiths J, Kerr CC, Stuart RM, Mistry D, Klein DJ, Viner RM, Bonell C. Determining the optimal strategy for reopening Schools, the impact of test and trace Interventions, and the risk of occurrence of a second COVID-19 epidemic wave in the UK: A modelling study. Lancet Child Adolesc Health. 2020;4:817\u201327. https:\/\/doi.org\/10.1016\/S2352-4642(20)30250-9<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Azzolina D, Comoretto R, Lanera C, Berchialla P, Baldi I, Gregori D. COVID-19 hospitalizations and patients\u2019 age at admission: the neglected importance of data variability for containment policies. Front Public Health. 2022;10. https:\/\/doi.org\/10.3389\/fpubh.2022.1002232<\/a>.<\/p>\n

Barcel\u00f3 MA, Saez M. Impact of the COVID-19 pandemic on the socioeconomic inequalities in mortality in Spanish provinces. J Epidemiol Glob Health. 2023;13:453\u201375. https:\/\/doi.org\/10.1007\/s44197-023-00125-0<\/a>.<\/p>\n


\n Google Scholar<\/a>\u00a0\n <\/p>\n

Fortunato F, Lillini R, Martinelli D, Iannelli G, Ascatigno L, Casanova G, Lopalco PL, Prato R. Association of Socio-Economic deprivation with COVID-19 incidence and fatality during the first wave of the pandemic in italy: lessons learned from a local Register-Based study. Int J Health Geogr. 2023;22(10). https:\/\/doi.org\/10.1186\/s12942-023-00332-9<\/a>.<\/p>\n

Setti L, Passarini F, De Gennaro G, Barbieri P, Licen S, Perrone MG, Piazzalunga A, Borelli M, Palmisani J, Di Gilio A, et al. Potential role of particulate matter in the spreading of COVID-19 in Northern italy: first observational study based on initial epidemic diffusion. BMJ Open. 2020;10:e039338. https:\/\/doi.org\/10.1136\/bmjopen-2020-039338<\/a>.<\/p>\n


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