Read Also<\/p>\n
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ICYMI: your national ag news recap for Dec. 5, 2025<\/p>\n
https:\/\/www.youtube.com\/watch?v=hyeHHkLrVFQ StatCan sees record Canadian wheat and canola crops Canadian wheat and canola production hit new record highs in the\u2026<\/p>\n
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WHY IT MATTERS: Unlocking greater knowledge of male infertility across species will aid productivity, including giving women a greater chance to conceive.<\/p>\n
Veterinarians do breeding soundness evaluations of bulls with physical examinations, measurement of scrotal circumstances and semen analysis for motility, density and morphology.<\/p>\n
\u201cWhen stem cells are producing new proteins, and their ability to produce new proteins, all those things are absolutely critical. Maybe at one point that knowledge we found could be translated to make diagnostic approaches for complementing what veterinarians are already doing. We can select better quality tools and improve fertility and thereby improving animal productivity,\u201d said Thundathil.<\/p>\n
\u201cThere are so many climate changes and environmental changes, all these things are happening, and at this point we don\u2019t know how these factors are actually contributing to the ability of sperm to produce new proteins. These are the future directions that we want to go.\u201d<\/p>\n
Thakor gave an example of a bull producing a million motile sperm, yet during capacitation, most of them turn out to be infertile.<\/p>\n
However, a bull that produces half as much sperm can yield many more fertile sperm in a more successful translation process.<\/p>\n
Examining the protein-making process and identifying its markers with more successful bulls has the possibility to increase production yields.<\/p>\n
\u201cWe should look more into molecular biomarkers of sperm to validate this further, so that we can achieve a better outcome for reproducibility of bulls,\u201d said Thakor.<\/p>\n
\u201cA bull is producing so many sperm, and they may be all motile, but what if they are not able to get capacitated in the female reproductive system due to maybe a defect in translation or the protein synthesis step. If we study that further, then maybe even low-sperm producing bulls can be more fertile in comparison to a bull that produces lot of sperm based on the markers.\u201d<\/p>\n
He said isolating the genes that are being activated and identifying what part of the fertility process they are responsible for opens up possibilities across species, including helping solve infertility problems in couples wanting to start a family.<\/p>\n
Male factors contribute to approximately half of infertility cases in humans, with unexplained infertility affecting one out of three couples.<\/p>\n
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