{"id":200462,"date":"2025-12-19T17:13:09","date_gmt":"2025-12-19T17:13:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/200462\/"},"modified":"2025-12-19T17:13:09","modified_gmt":"2025-12-19T17:13:09","slug":"ohsu-study-finds-exposure-to-common-air-pollutants-alters-adolescent-brain-development","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/200462\/","title":{"rendered":"OHSU study finds exposure to common air pollutants alters adolescent brain development"},"content":{"rendered":"

\"A<\/p>\n

For the first time, researchers at OHSU evaluated the long-term impact of air pollution on adolescent brain health and development. (Getty IMage)<\/p>\n

Physician-scientists at Oregon Health & Science University\u00a0warn that exposure to air pollution may have serious implications for a child\u2019s developing brain.<\/p>\n

In a recent study<\/a> published in the journal Environmental Research, researchers in OHSU\u2019s Developmental Brain Imaging Lab<\/a> found that air pollution is associated with structural changes in the adolescent brain, specifically in the frontal and temporal regions \u2014 the areas responsible for executive function, language, mood regulation and socioemotional processing.<\/p>\n

Air pollution causes harmful contaminants, such as particulate matter, nitrogen dioxide and ozone, to circulate in the environment. It has been exacerbated over the past two centuries by industrialization, vehicle emissions, and, more recently, wildfires.<\/p>\n

While research has established that pollution contributes to various physical health issues like respiratory disorders, cardiovascular diseases and metabolic dysfunction, its effects on neurocognitive health aren\u2019t as well understood.<\/p>\n

OHSU researchers leveraged the ABCD Study<\/a> \u2014 the largest longitudinal study of adolescent brain development in the United States \u2014 to better understand how exposure to specific air pollutants might affect adolescents, who are undergoing critical periods of brain development and may be especially vulnerable to exposures.<\/p>\n

This was one of the first studies to examine air pollution\u2019s impact on structural changes in the adolescent brain over time.<\/p>\n

\"Calvin<\/p>\n

Calvin Jara, M.D. (OHSU)<\/p>\n

\u201cWhat\u2019s perhaps most concerning is that this study didn\u2019t look at rare toxins; it looked at everyday, common pollutants that all of us are exposed to walking around and breathing in the air outside,\u201d said Calvin Jara, M.D., resident in otolaryngology\/head and neck surgeries in the OHSU School of Medicine and lead author of the study. \u201cWhat we discovered was a slow and subtle effect happening on the brain, and while it might not be causing symptoms immediately, it could be shifting developmental trajectories and outcomes over time.\u201d<\/p>\n

In an analysis of nearly 11,000 children in the ABCD study dataset, researchers found that baseline exposure to specific air pollutants in the early phase of adolescence, or the onset of puberty, generally ages 9 to 10, was associated with both persistent and developmental changes in cortical thickness, a measurement of the structural maturation of the outer layer of the brain. Atypical cortical thinning, especially thinning that is accelerated, can be an indication of an underlying neurological disruption and result in associated cognitive impairment.<\/p>\n

While the issue is more severe in urban areas, researchers note that they\u2019re seeing these changes even in children exposed to pollution at levels below what the Environmental Protection Agency marks as \u201csafe.\u201d<\/p>\n

\u201cThese data show this is not just about a single child,\u201d Jara said. \u201cIt\u2019s about what\u2019s happening to millions of children around the world who are exposed to low levels of air pollution for years on end.\u201d<\/p>\n

Researchers warn that these structural changes in the brain could have impacts on a child\u2019s overall health, well-being and life trajectory. Alterations in the development of these critical brain regions\u00a0could impair attention, memory and emotional regulation, potentially leading to academic difficulties and behavioral concerns. Future research should continue to examine these broader long-term consequences, researchers said.<\/p>\n

Combating widespread pollution requires collaborative efforts outside of clinic spaces, researchers note. While individual clinicians can\u2019t directly change air quality, they can educate and advocate for system-level change. Policy efforts aimed at reducing air pollution, including those focused on cleaner transportation and infrastructure, improved access to green spaces and stricter air quality standards, will be critical for promoting healthy brain development, Jara said.<\/p>\n

Additionally, clinicians must continually consider the growing role environmental health factors play in their patients\u2019 treatment and care.<\/p>\n

\"Bonnie<\/p>\n

Bonnie Nagel, Ph.D. (OHSU)<\/p>\n

\u201cEnvironmental factors have a huge impact on how healthy children can be, and ultimately how healthy they\u2019ll be over their lifetime,\u201d said Bonnie Nagel, Ph.D., OHSU\u2019s Interim Chief Research Officer, executive vice president and the study\u2019s co-author. \u201cThis work adds to the growing body of evidence that pollution is not just an environmental issue; it\u2019s a significant and growing health issue, especially for our youngest and most vulnerable.\u201d<\/p>\n

Research reported in this publication was supported by philanthropic funding through the Center for Mental Health Innovation (CMHI) at\u00a0Oregon Health & Science University\u00a0(OHSU); the\u00a0OHSU\u00a0Advanced Imaging Research Center and the Oregon Opportunity Partnership for Advancing Biomedical Research; the Office of the Director, of the National Institutes of Health, Award number S10OD021701, which funded the 3T Siemens Prisma MRI instrument, and Award number S10OD016356, which funded a 32-channel radio-frequency head coil, both housed in OHSU’s Advanced Imaging Research Center; as well as by the National Institute on Drug Abuse, of the National Institutes of Health, Award number U01DA041148. <\/p>\n","protected":false},"excerpt":{"rendered":"For the first time, researchers at OHSU evaluated the long-term impact of air pollution on adolescent brain health…\n","protected":false},"author":2,"featured_media":200463,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[29977,103,61,60,100932,13483],"class_list":["post-200462","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-child","tag-health","tag-ie","tag-ireland","tag-oregon-health-amp-science-university-ohsu","tag-pollution"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/200462","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=200462"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/200462\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/200463"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=200462"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=200462"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=200462"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}