{"id":288826,"date":"2026-02-09T14:08:19","date_gmt":"2026-02-09T14:08:19","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/288826\/"},"modified":"2026-02-09T14:08:19","modified_gmt":"2026-02-09T14:08:19","slug":"takeda-deepens-ai-drug-discovery-push-with-1-7-billion-iambic-deal","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/288826\/","title":{"rendered":"Takeda deepens AI drug discovery push with $1.7 billion Iambic deal"},"content":{"rendered":"\n<p class=\"yf-vbsvxt\">By Kamal Choudhury<\/p>\n<p class=\"yf-vbsvxt\">Feb 9 (Reuters) &#8211; Privately held Iambic said on Monday it has entered a multi-year partnership worth more than $1.7 billion \u200bwith Japan&#8217;s Takeda Pharmaceutical to use <a href=\"https:\/\/tech.yahoo.com\/ai\/\" data-ylk=\"slk:artificial intelligence;elm:context_link;itc:0;sec:content-canvas\" class=\"link \" rel=\"nofollow noopener\" target=\"_blank\">artificial intelligence<\/a> to help \u200cdesign small-molecule drugs targeting cancer and gastrointestinal diseases.<\/p>\n<p class=\"yf-vbsvxt\">Under the agreement, Iambic will receive upfront payments \u200cand could earn more than $1.7 billion in development and commercial milestones, plus royalties on sales.<\/p>\n<p class=\"yf-vbsvxt\">The deal marks Takeda&#8217;s latest move to embed artificial intelligence across its research operations, following a similar agreement with Nabla Bio last year \u2060focused on protein-based drugs.<\/p>\n<p class=\"yf-vbsvxt\">Drug \u200cdevelopers are increasingly turning to AI technologies to speed up discovery and cut costs, with experts predicting timelines could \u200dbe halved in coming years.<\/p>\n<p class=\"yf-vbsvxt\">Takeda will also gain access to NeuralPLexer, Iambic&#8217;s model that predicts how drug molecules bind to proteins.<\/p>\n<p class=\"yf-vbsvxt\">Iambic Chief Executive Tom Miller told Reuters \u200bthat understanding protein structure is critical in drug development.<\/p>\n<p class=\"yf-vbsvxt\">&#8220;If you don&#8217;t \u200cknow the shape of what you&#8217;re trying to engage &#8230; it&#8217;s a lot like trying to make a sculpture in the dark,&#8221; he said.<\/p>\n<p class=\"yf-vbsvxt\">Traditional drug discovery can take around six years before a compound reaches clinical trials.<\/p>\n<p class=\"yf-vbsvxt\">Iambic said its approach, combining AI predictions with automated laboratories, can compress that \u2060timeline to less than two years.<\/p>\n<p class=\"yf-vbsvxt\">Takeda Chief \u200bScientific Officer Christopher Arendt said the technology \u200bcould significantly shorten research timelines, though speed is only part of the appeal.<\/p>\n<p class=\"yf-vbsvxt\">&#8220;When you start to add an AI \u200dengine to your small\u2011molecule \u2060drug development, it means you can go faster,&#8221; Arendt said in an interview, adding that molecular quality is equally critical.<\/p>\n<p class=\"yf-vbsvxt\">Miller said AI \u2060tools can save months of traditional lab work, but &#8220;the most important thing is creating \u200csomething that couldn&#8217;t have been done before.&#8221;<\/p>\n<p class=\"yf-vbsvxt\">(Reporting by Kamal Choudhury \u200cin Bengaluru; Editing by Tasim Zahid)<\/p>\n","protected":false},"excerpt":{"rendered":"By Kamal Choudhury Feb 9 (Reuters) &#8211; Privately held Iambic said on Monday it has entered a multi-year&hellip;\n","protected":false},"author":2,"featured_media":288827,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20],"tags":[220,218,219,10818,138534,61,60,138533,80,138535],"class_list":{"0":"post-288826","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-artificial-intelligence","8":"tag-ai","9":"tag-artificial-intelligence","10":"tag-artificialintelligence","11":"tag-drug-development","12":"tag-iambic","13":"tag-ie","14":"tag-ireland","15":"tag-takeda-pharmaceutical","16":"tag-technology","17":"tag-tom-miller"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/288826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=288826"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/288826\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/288827"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=288826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=288826"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=288826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}