{"id":327307,"date":"2026-03-03T21:35:12","date_gmt":"2026-03-03T21:35:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/327307\/"},"modified":"2026-03-03T21:35:12","modified_gmt":"2026-03-03T21:35:12","slug":"dr-soheil-meshinchi-a-leading-expert-in-acute-myeloid-leukemia-named-dylan-burke-endowed-chair-in-immunotherapy","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/327307\/","title":{"rendered":"Dr. Soheil Meshinchi, a leading expert in acute myeloid leukemia, named Dylan Burke Endowed Chair in Immunotherapy"},"content":{"rendered":"<p>As a child, Dylan Burke was an athlete and\u00a0gymnast\u00a0who\u00a0shunned sugar and\u00a0worked out every day, and a budding mad scientist who was constantly inventing things. As a\u00a0patient,\u00a0he\u00a0grew\u00a0interested in neuropharmacology and the chemical basis for happiness, reading journal papers together with his father.\u00a0\u00a0<\/p>\n<p>Dylan\u00a0was diagnosed\u00a0at age 9\u00a0with\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/diseases\/myelodysplastic-syndrome.html\" rel=\"nofollow noopener\" target=\"_blank\">myelodysplastic syndrome\u00a0(MDS)<\/a>,\u00a0a group of diseases characterized by\u00a0abnormal production of blood cells in bone marrow.\u00a0MDS commonly progresses to\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/diseases\/leukemia.html\" rel=\"nofollow noopener\" target=\"_blank\">leukemia<\/a>, and that was sadly Dylan\u2019s experience.\u00a0He\u00a0came to Fred Hutch Cancer Center\u00a0in 2019\u00a0for treatment\u00a0after his father, Dave Burke,\u00a0read a pediatric oncology textbook that included a chapter on MDS written by\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/faculty-lab-directory\/meshinchi-soheil.html\" rel=\"nofollow noopener\" target=\"_blank\">Soheil Meshinchi,\u00a0MD, PhD<\/a>,\u00a0a hematologist\/oncologist and\u00a0professor in the\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/research\/divisions\/translational-science-and-therapeutics-division.html\" rel=\"nofollow noopener\" target=\"_blank\">Translational Science and Therapeutics Division<\/a>\u00a0at Fred Hutch and a member of its <a href=\"https:\/\/www.fredhutch.org\/en\/research\/institutes-networks-ircs\/immunotherapy-integrated-research-center.html\" rel=\"nofollow noopener\" target=\"_blank\">Immunotherapy\u00a0Integrated Research Center<\/a>.<\/p>\n<p>\u201cSoheil was largely the reason we chose Fred Hutch and Seattle Children\u2019s Hospital,\u201d said Burke, a Google advisor and chief technology officer at the <a href=\"https:\/\/arcinstitute.org\/\" target=\"_blank\" rel=\"noopener noreferrer nofollow\">Arc Institute<\/a>, a biomedical research organization in Palo Alto, Calif. \u201cHe\u2019s\u00a0a\u00a0really creative\u00a0scientist and clinician who\u00a0thinks outside the box\u00a0and is disruptive and makes things happen. He is persistent.\u00a0I have seen him fight not just for Dylan but for other children.\u201d\u00a0<\/p>\n<p>Meshinchi, a world leader in\u00a0developing novel approaches to treating\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/diseases\/acute-myeloid-leukemia.html\" rel=\"nofollow noopener\" target=\"_blank\">acute myeloid leukemia\u00a0(AML)<\/a>, has been named the\u00a0second\u00a0recipient of the\u00a0Dylan Burke Endowed Chair in Immunotherapy.\u00a0Fred Hutch immunologist <a href=\"https:\/\/www.fredhutch.org\/en\/faculty-lab-directory\/riddell-stanley.html\" rel=\"nofollow noopener\" target=\"_blank\">Stan\u00a0Riddell,\u00a0MD,<\/a>\u00a0served at\u00a0the inaugural\u00a0holder\u00a0of the chair, which Burke and his wife, Louise O\u2019Reilly,\u00a0established\u00a0in 2020.\u00a0<\/p>\n<p>Dylan received a\u00a0<a href=\"https:\/\/www.fredhutch.org\/en\/patient-care\/treatments\/blood-marrow-transplant.html\" rel=\"nofollow noopener\" target=\"_blank\">bone marrow transplant<\/a>\u00a0at Fred Hutch and was in remission for\u00a0nearly two\u00a0years when he relapsed. His cancer had\u00a0acquired\u00a0new mutations, which\u00a0required\u00a0new treatments.\u00a0Dylan\u2019s medical team performed molecular analyses of his cancer, searching for changes in genes or specific proteins\u00a0to help\u00a0create\u00a0a targeted treatment plan for Dylan. With\u00a0Meshinchi\u2019s\u00a0support, Dylan\u2019s\u00a0family pursued\u00a0several drugs that had not yet been used in pediatric patients,\u00a0including one that targeted the TP53 mutation that defined Dylan\u2019s disease.\u00a0\u00a0<\/p>\n<p>Dylan underwent a second transplant. When\u00a0that\u00a0didn\u2019t\u00a0control the cancer, Dylan\u2019s parents tried\u00a0other options including working with a start-up lab to design an assay, or\u00a0test,\u00a0that would yield a personalized chemotherapy plan.\u00a0None of the approaches managed to\u00a0contain\u00a0the cancer, and Dylan died on\u00a0June 26,\u00a02022.\u00a0\u00a0<\/p>\n<p>\u201cDylan never wanted to give up, and Soheil was an awesome partner,\u201d said Burke.\u00a0\u201cPediatric oncology as\u00a0a\u00a0vocation\u00a0is incredibly tough.\u00a0Soheil works so hard to push the science forward to help these kids.\u201d\u00a0<\/p>\n<p>He and O\u2019Reilly decided to endow the chair when Dylan was in remission.<\/p>\n<p>\u201cWe wanted to\u00a0give\u00a0back a little,\u201d he said.\u00a0\u201cI\u2019m\u00a0a big believer in harnessing the body\u2019s immune system to fight cancer.\u00a0Our goal is to accelerate the research that enhances this natural defense.\u201d\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"As a child, Dylan Burke was an athlete and\u00a0gymnast\u00a0who\u00a0shunned sugar and\u00a0worked out every day, and a budding mad&hellip;\n","protected":false},"author":2,"featured_media":327308,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[67173,151423,151417,151422,151421,103,61,8267,151420,151418,60,151419],"class_list":["post-327307","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-acute-myeloid-leukemia","tag-aml-treatment","tag-aml-treatment-tools","tag-endowed-chair","tag-endowed-chair-donors","tag-health","tag-ie","tag-immunotherapy","tag-immunotherapy-irc-iirc","tag-immunotherapy-treatment","tag-ireland","tag-soheil-meshinchi"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/327307","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=327307"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/327307\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/327308"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=327307"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=327307"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=327307"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}