{"id":399703,"date":"2026-04-15T12:23:11","date_gmt":"2026-04-15T12:23:11","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/399703\/"},"modified":"2026-04-15T12:23:11","modified_gmt":"2026-04-15T12:23:11","slug":"brain-cancer-clinical-trial-aims-to-bring-hope","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/399703\/","title":{"rendered":"Brain cancer clinical trial aims to &#8216;bring hope&#8217;"},"content":{"rendered":"<p class=\"mb-4 text-lg md:leading-8 break-words\">A \u00a36.9m clinical trial programme that aims to improve brain cancer treatment for patients in Yorkshire has been launched by a charity.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The project, funded by Yorkshire Cancer Research, involves changing the way drug effectiveness is tested in people with recurrent glioblastoma &#8211; the most common and fastest-growing type of brain cancer.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Each year, about 247 people in Yorkshire are diagnosed with glioblastoma and about 181 people die, the charity said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Emma Ward, who was diagnosed with a fast-growing tumour in 2025, said the trials would &#8220;bring hope right here to our region&#8221;, where survival rates are lower than the national average.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The 47-year-old from York said: &#8220;For families like mine facing brain cancer, time means everything.&#8221;<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">She said the research programme, called EPIC-GB, was the &#8220;only way to give families more time to make memories together&#8221;.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The trials, which aim to enable patients to access trial treatments earlier, will be delivered in Sheffield, Leeds and Hull.<\/p>\n<p><img alt=\"A lady in a blue blouse, from the earlier picture. She stands with a tall bald man with a dark green t shirt. Two girls who appear in their teens or early 20s stand next to them. They all have arms around each other and are smiling at the camera.\" loading=\"lazy\" width=\"960\" height=\"540\" decoding=\"async\" data-nimg=\"1\" class=\"rounded-lg\" style=\"color:transparent\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2026\/04\/5a2f45693b4a8999d242073d5058a449.jpeg\"\/><\/p>\n<p>Emma Ward travelled abroad for treatment, funded by \u00a3145,000 raised by friends and family [Yorkshire Cancer Research]<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Many existing cancer drugs are ineffective at treating glioblastoma due to the protective layer around the brain preventing access to tumours, the charity said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The clinical trials will see participants start new treatments before having surgery, meaning tumour tissue removed in operations can be studied to show which drugs have been successful.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">This means ineffective drugs can be dropped sooner, avoiding unnecessary side effects and switching to better options faster.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Yorkshire Cancer Research said there had not been any &#8220;significant&#8221; breakthroughs in treating glioblastoma in nearly 20 years.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Ward, who raised \u00a3145,000 to access immunotherapy abroad last year, said: &#8220;Too many people lose their lives because there are so few options for treating brain cancers.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;It feels as though brain cancers have been placed in the &#8216;too hard&#8217; box, so investment in research is held back out of fear nothing will work.&#8221;<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">She added: &#8220;When the time comes, I don&#8217;t want my daughters and husband to think of me in hospital or going through treatment.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;I want them to remember the trips we took, dancing in the kitchen, the laughter and all those happy times we shared as a family.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;Only through more research can we give families more of those memories.&#8221;<\/p>\n<p><img alt=\"A man with a shaved head, short goatee and white shirt, in front of a blurred lab background, smiles at the camera.\" loading=\"lazy\" width=\"939\" height=\"528\" decoding=\"async\" data-nimg=\"1\" class=\"rounded-lg\" style=\"color:transparent\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2026\/04\/7b6eb6aefbfa3d1624ff4ca3f23cf67b.jpeg\"\/><\/p>\n<p>Researcher Ola Riminiyi said the study was a &#8220;vital step forward&#8221; [Yorkshire Cancer Research]<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">The charity said reasons for Yorkshire&#8217;s lower survival rate included the size of the region and higher levels of deprivation in some areas.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Ola Rominiyi, clinical lecturer in neurosurgery at the University of Sheffield and neurosurgical resident at Sheffield Teaching Hospitals NHS Trust, said current treatments were &#8220;not good enough&#8221; to resist the &#8220;aggressive&#8221; disease.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;We&#8217;re optimistic this new study is a vital step forward, ensuring more people can access promising new treatments and giving hope where options have too often been limited,&#8221; he said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Dr Stuart Griffiths, director of research, policy and impact at Yorkshire Cancer Research said he hoped the programme would &#8220;help position Yorkshire as an attractive region for future investment in clinical trials&#8221;.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">&#8220;This ground-breaking study shows the charity&#8217;s commitment to bringing innovative clinical trials to Yorkshire, so people in the region can be among the first to benefit from pioneering cancer breakthroughs,&#8221; he said.<\/p>\n<p class=\"mb-4 text-lg md:leading-8 break-words\">Listen to highlights from <a href=\"https:\/\/www.bbc.co.uk\/sounds\/curation\/p0cjf284?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Blink%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:North Yorkshire on BBC Sounds;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;North Yorkshire on BBC Sounds&quot;}\" class=\"link \">North Yorkshire on BBC Sounds<\/a>, catch up with the latest <a href=\"https:\/\/www.bbc.co.uk\/programmes\/b006mj5m?xtor=AL-72-%5Bpartner%5D-%5Byahoo.north.america%5D-%5Blink%5D-%5Bnews%5D-%5Bbizdev%5D-%5Bisapi%5D\" rel=\"nofollow noopener\" target=\"_blank\" data-ylk=\"slk:episode of Look North;elm:context_link;itc:0;sec:content-canvas\" data-yga=\"{&quot;yLinkElement&quot;:&quot;context_link&quot;,&quot;yModuleName&quot;:&quot;content-canvas&quot;,&quot;yLinkText&quot;:&quot;episode of Look North&quot;}\" class=\"link \">episode of Look North<\/a><\/p>\n<p>More on this storyRelated internet links<\/p>\n","protected":false},"excerpt":{"rendered":"A \u00a36.9m clinical trial programme that aims to improve brain cancer treatment for patients in Yorkshire has been&hellip;\n","protected":false},"author":2,"featured_media":399704,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[9607,176478,2996,176477,103,61,60,176479,176476],"class_list":{"0":"post-399703","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-brain-cancer","9":"tag-cancer-drugs","10":"tag-clinical-trial","11":"tag-emma-ward","12":"tag-health","13":"tag-ie","14":"tag-ireland","15":"tag-recurrent-glioblastoma","16":"tag-yorkshire-cancer-research"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/399703","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=399703"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/399703\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/399704"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=399703"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=399703"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=399703"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}