{"id":407489,"date":"2026-04-20T00:54:21","date_gmt":"2026-04-20T00:54:21","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/407489\/"},"modified":"2026-04-20T00:54:21","modified_gmt":"2026-04-20T00:54:21","slug":"luke-oneill-cancer-is-becoming-a-chronic-disease","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/407489\/","title":{"rendered":"Luke O&#8217;Neill: Cancer is becoming a chronic disease"},"content":{"rendered":"<p class=\"font-weight-bold\">Luke O\u2019Neill told The Pat Kenny Show, that new cancer treatments are extending patients lifespans<\/p>\n<p>There is good news for pancreatic and ovarian cancer treatment which are some of the most aggressive cancers.\u00a0<\/p>\n<p>Usually, once the diagnosis is processed, it means the stage of the cancer is quite advanced.\u00a0<\/p>\n<p><a href=\"https:\/\/www.google.com\/url?sa=t&amp;source=web&amp;rct=j&amp;opi=89978449&amp;url=https:\/\/www.newstalk.com\/podcasts\/highlights-from-the-pat-kenny-show\/luke-oneill-with-some-promising-advances-in-treating-pancreatic-ovarian-cancer&amp;ved=2ahUKEwjJnKeVnPiTAxXkXUEAHZbEAkAQFnoECBoQAQ&amp;usg=AOvVaw2wu_ky9V69HeDmsvjzgFqN\" rel=\"nofollow noopener\" target=\"_blank\">A new trial<\/a> has shown a doubling of the survival time for pancreatic cancer. Usually, patients have 7 months left following a diagnosis. This trial extends this to 14 months.\u00a0<\/p>\n<p>Dr O\u2019Neill told <a href=\"https:\/\/www.google.com\/url?sa=t&amp;source=web&amp;rct=j&amp;opi=89978449&amp;url=https:\/\/www.newstalk.com\/shows\/pat-kenny-show-234857&amp;ved=2ahUKEwjalp7tnPiTAxW7TEEAHdmPEVEQFnoECDQQAQ&amp;usg=AOvVaw3XburQHS43L1ZHoGnwOsKt\" rel=\"nofollow noopener\" target=\"_blank\">The Pat Kenny Show<\/a>, that it would have a \u2018big effect on people\u2019.<\/p>\n<p>The drug called Daroxanrazib, targets the RAS gene, often found to have mutated in cancer.\u00a0<\/p>\n<p>\u201cThis drug really blocks RAS. That&#8217;s why they think it&#8217;s so effective.<\/p>\n<p>\u201cIf you knock it down, the cancer stops growing. It\u2019s unprecedented for pancreatic cancer.\u00a0<\/p>\n<p>\u201cLots of patients were given the drug and they see this doubling in survival. That gives us huge confidence that it really works.\u201d<\/p>\n<p>One of the first people to undergo treatment on the drug was former Republican Senator Ben Sass who said that while his tumours decreased by 76% in the first week, he got rashes as a side effect from the drug.\u00a0<\/p>\n<p><img decoding=\"async\" class=\"size-full wp-image-2147940\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2025\/09\/CWEGB8.jpg\" alt=\"\"\/><\/p>\n<p>Dr O\u2019Neill said it was \u201cquite surprising\u201d that the breakthrough treatment for ovarian cancer was previously used for Cushing\u2019s disease (a condition where the patient produces too much cortisol).\u00a0<\/p>\n<p>The drug, called Relacortisant, worked for both illnesses and allowed for a <a href=\"https:\/\/www.newstalk.com\/news\/whats-causing-the-rise-in-bowel-cancer-among-young-adults-2224422\" rel=\"nofollow noopener\" target=\"_blank\">36% reduction of death for ovarian cancer.\u00a0<\/a><\/p>\n<p>Dr Luke O\u2019Neill told the Pat Kenny Show that while these results were encouraging, researchers were hoping to get even better ones.\u00a0<\/p>\n<p>\u201cA drug called Mo-Rez got a 62% response rate,which meant 62% of people responded really well.\u00a0<\/p>\n<p>\u201cTheir tumors shrank, Pat, and were eliminated with ovarian cancer.\u00a0<\/p>\n<p>\u201cThere&#8217;s been a few ideas around this already in the past. This is probably the first example of it really working. Cancer is becoming a chronic disease.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"Luke O\u2019Neill told The Pat Kenny Show, that new cancer treatments are extending patients lifespans There is good&hellip;\n","protected":false},"author":2,"featured_media":407490,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5],"tags":[72,61,60],"class_list":{"0":"post-407489","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-business","8":"tag-business","9":"tag-ie","10":"tag-ireland"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/407489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=407489"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/407489\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/407490"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=407489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=407489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=407489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}