{"id":410238,"date":"2026-04-21T15:57:20","date_gmt":"2026-04-21T15:57:20","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/410238\/"},"modified":"2026-04-21T15:57:20","modified_gmt":"2026-04-21T15:57:20","slug":"patient-surgeon-sex-mismatch-doesnt-drive-disparities-in-cardiac-surgery","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/410238\/","title":{"rendered":"Patient-Surgeon Sex Mismatch Doesn\u2019t Drive Disparities in Cardiac Surgery"},"content":{"rendered":"<p>\n      The search for the reason why women have worse surgical outcomes than men continues.\n  <\/p>\n<p>Sex discordance isn\u2019t an explanation for gender disparities in outcomes after cardiac surgery, new data suggest. For men, whether their surgeon was male had no impact on morbidity and mortality at 30 days or 5 years. Similarly, women had the same outcomes regardless of whether they were treated by a female or male surgeon.<\/p>\n<p>The study, led by Lamia Harik, MD, and Alexander C. Gregg, MD (both from Weill Cornell Medicine, New York, NY), was <a href=\"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.125.048015\" rel=\"nofollow noopener\" target=\"_blank\">published recently<\/a> in the Journal of the American Heart Association.<\/p>\n<p>Speaking with TCTMD, Harik said that the concept of sex discordance is fairly novel and that it\u2019s the first time such a lens has been applied to cardiac surgery. Literature on <a href=\"https:\/\/jamanetwork.com\/journals\/jamasurgery\/fullarticle\/2786671\" rel=\"nofollow noopener\" target=\"_blank\">general surgery<\/a> has suggested the factor might explain sex disparities, though this is not what they found here.<\/p>\n<p>Mario Gaudino, MD, PhD (Weill Cornell Medicine), noted that it\u2019s well known that women generally fare worse than men after cardiac surgery. <\/p>\n<p>\u201cThis is something that is becoming more and more evident. I think we as a community are guilty of the fact that we have ignored this issue for a long time,\u201d he told TCTMD. Many had hoped the gap would narrow as cardiac surgery as a whole improved, but \u201cthis is not the case. There is still a very large gap in outcome between sexes, with women having worse outcomes. So we need to investigate the reason for that.\u201d<\/p>\n<p>Gaudino and Harik suggest that cardiac surgery\u2019s team-based approach may be why it wasn\u2019t swayed by discordance.<\/p>\n<p>\u201cThe cardiac anesthesiologist, cardiologist, interventional cardiologist, and perfusionists all play a key role in getting patients to, and through, a cardiac surgery. The surgeon is only one operator who is part of a larger team; thus, the effect of the individual surgeon on outcomes may be somewhat mitigated,\u201d the investigators write.<\/p>\n<p>On top of this, \u201ccardiac surgery is a more standardized field than general surgery,\u201d they note, adding that \u201cthe relatively longer training pathway of cardiac surgery may minimize technical skill disparities among surgeons, such that there is less intraoperator variability in cardiac surgery by the time attendinghood is reached.\u201d<\/p>\n<p>The idea in their research, said Harik, was to ask:\u200a\u201cWhat\u2019s modifiable? What can we actually fix rather than throwing our hands up and just sort of accepting this disparity as the status quo?\u201d In addition to exploring concordance, Harik and colleagues previously looked at <a href=\"https:\/\/www.jacc.org\/doi\/10.1016\/j.jacc.2023.12.032\" rel=\"nofollow noopener\" target=\"_blank\">intraoperative anemia<\/a> in CABG and identified it as a key mediator.<\/p>\n<p>Discordance Not a Driver<\/p>\n<p>The researchers analyzed data from 223,065 Medicare beneficiaries (68.2% male) who underwent coronary artery bypass grafting, surgical aortic valve replacement, and\/or proximal aortic surgery from 2010 to 2021. Stratified by sex, 59.9% of the cases involved a patient and surgeon who were both male, 28.0% a female patient with a male surgeon, 8.3% a male patient with a female surgeon, and 3.8% a female patient and surgeon.<\/p>\n<p>At 30 days, the mortality rate was 4.1%, while the rate of mortality plus morbidity (MI, stroke, and all-cause readmission) was 30.1%. There was no difference in the composite between men who were treated by a male versus female surgeon (27.6% vs 27.4%) or between women who were treated by a male versus female surgeon (35.5% vs 35.1%). Although there was an imbalance between the concordant and discordant groups (28.0% vs 33.6%; P &lt; 0.001), on multivariable regression analysis the patient\/surgeon mismatch was not independently associated with outcomes (OR 1.00; 95% CI 0.96-1.04). There also was no interaction between patient sex and sex discordance for outcomes (P = 0.75).<\/p>\n<p>At 5 years, the morbidity and mortality rate was higher for male patients treated by a man (67.2%) than those treated by a woman (65.3%; P &lt; 0.001). Among female patients, it was higher for those treated by a man compared with by a woman (75.7% vs 74.0%; P = 0.0006). Again, though, discordance was not independently associated with outcome (HR 1.00; 95% CI 0.98-1.02) and there was no interaction between patient sex and discordance (P= 0.89).<\/p>\n<p>I think of [our study] as a starting point and not an ending point. Lamia Harik<\/p>\n<p>Harik said a limitation of their study is that some Medicare beneficiaries did not have their surgeon\u2019s sex recorded in the database. Additionally, the number of women with female surgeons was quite small. \u201cI wouldn\u2019t say that our retrospective study is the final word on the topic. I think of it as a starting point and not an ending point,\u201d she stressed. Additionally, it speaks to \u201cthe need to have more female providers in cardiac surgery.\u201d<\/p>\n<p>Gaudino, for his part, noted that while their analysis didn\u2019t confirm their initial hypothesis that sex concordance affected outcomes in this setting, it wasn\u2019t done in vain. \u201c\u200aThe process of eliminating hypotheses that are not true is actually very important,\u201d he said.<\/p>\n<p>Going forward, it will be important for cardiac surgery databases to collect more information on the surgeons themselves so that it\u2019s possible to dig into any patterns that emerge, Harik and Gaudino both stressed.<\/p>\n<p>The current study, Gaudino said, \u201crepresents an interesting change in the focus of outcomes research from the patient to the provider.\u201d An example of this is the potential relevance of group dynamics, such as how different surgeons and anesthesiologists interact.<\/p>\n<p>Notably, the <a href=\"https:\/\/www.tctmd.com\/news\/first-ever-cardiac-surgery-trial-women-poised-launch-roma-women\" rel=\"nofollow noopener\" target=\"_blank\">ROMA-Women trial<\/a>, the first in cardiac surgery to be devoted entirely to women, is collecting details on providers, Harik said. \u201c\u200aWe\u2019re collecting the kind of data that we don\u2019t see available in current databases for our prospective randomized study.\u201d<\/p>\n<p>Gaudino urged that a key way to improve female patients\u2019 outcomes in cardiac surgery is to have more female clinicians and investigators involved in research. \u201cUnfortunately, there\u2019s no doubt that one of the reasons why we have such limited information on cardiac surgery in women is because so far most cardiac surgeons have been men and research . . . has been mostly done by men,\u201d he commented, predicting that the younger generation of cardiac surgeons, increasingly more of them female, will be better equipped to pinpoint what\u2019s driving sex disparities.<\/p>\n","protected":false},"excerpt":{"rendered":"The search for the reason why women have worse surgical outcomes than men continues. Sex discordance isn\u2019t an&hellip;\n","protected":false},"author":2,"featured_media":410239,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60],"class_list":{"0":"post-410238","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-health","9":"tag-ie","10":"tag-ireland"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/410238","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=410238"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/410238\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/410239"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=410238"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=410238"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=410238"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}