{"id":413095,"date":"2026-04-23T07:50:13","date_gmt":"2026-04-23T07:50:13","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/413095\/"},"modified":"2026-04-23T07:50:13","modified_gmt":"2026-04-23T07:50:13","slug":"how-in-silico-microbiome-modelling-is-reshaping-supplement-formulation","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/413095\/","title":{"rendered":"how in silico microbiome modelling is reshaping supplement formulation"},"content":{"rendered":"

For much of the history of nutraceuticals, ingredient selection has been guided by association: epidemiological observations, animal studies and small human trials showing that a given fibre or botanical correlates with a health outcome.<\/p>\n

The mechanism, what the gut microbiome does with an ingredient, has largely remained a black box.<\/p>\n

A London-based biotechnology company, Enbiosis Biotechnologies, is working to change that logic.<\/p>\n

Their platform uses genome-scale metabolic models of gut bacteria and an AI retrosynthesis engine to predict which food-grade precursors will produce targeted health-promoting metabolites in a patient population’s microbiome before clinical studies begin.\u00a0<\/p>\n

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\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"For much of the history of nutraceuticals, ingredient selection has been guided by association: epidemiological observations, animal studies…\n","protected":false},"author":2,"featured_media":413096,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60],"class_list":{"0":"post-413095","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-health","9":"tag-ie","10":"tag-ireland"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/413095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=413095"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/413095\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/413096"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=413095"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=413095"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=413095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}