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iStock.com\/SDI Productions<\/p>\n
Patients with cancer who developed sepsis were more likely to have a \u201chigher association\u201d with various risk factors that affect the outcomes of sepsis, such as older age, lower BMI, and other factors, according to results from a recent study.<\/p>\n
Christopher Pope, MD, of Cooper University Hospital, and colleagues conducted the study and published their findings as an abstract during the National Comprehensive Cancer Network 2026 Annual Conference.<\/p>\n
According to the investigators, \u201ccancer and its various treatment modalities increase susceptibility to the development of sepsis.\u201d Their goal was to explore \u201cthe difference in risk factors and outcomes of sepsis\u201d in patients with cancer and patients with sepsis who did not have cancer.<\/p>\n
The study included all adult patients who received treatment for sepsis at a \u201curban tertiary healthcare center.\u201d Investigators performed a retrospective cohort analysis and split the patients into two groups comprised of individuals with cancer who developed sepsis (n=310) and patients who developed sepsis but did not have cancer (n=628).<\/p>\n
The results revealed \u201chigher associations of certain variables\u201d in the cohort with cancer versus the cohort without cancer, including \u201cmale sex (55.8 vs 48.2%; P=0.029), White race (60.6 vs 51.7%; P=0.001), lower BMI (28.10+\/-9.3 vs 30.02+\/-10.4 kg\/m2; P=0.004) and history of transient ischemic attack (6.1 vs 2.7%; P=0.010).\u201d<\/p>\n
Lower associations were also observed in the cohort with cancer compared to the cohort without cancer, including \u201crecreational drug use (10.0 vs 17.0%; P=0.004) and diabetes mellitus (35.9 vs 45.9%; P=0.004).\u201d<\/p>\n
The investigators also performed a simple linear regression, which found that patients with cancer who developed sepsis had lower hospital stays. However, the study\u2019s logistic regression model demonstrated that individuals with cancer had \u201cincreased odds of all-cause mortality (OR, 1.822; 95% CI, 1.350-2.460; P<0.001).<\/p>\n
In reflecting on the results, the investigators underscored that although patients with cancer were more likely to experience all-cause mortality, they also had \u201ccomparable readmission rates, bloodstream infection, and in-hospital mortality.\u201d<\/p>\n
Overall, patients with cancer who were diagnosed with sepsis had higher associations with risk factors, such as older age, lower BMI, White race, male sex, and a history of transient ischemic attack, and lower associations with risk factors, such as recreational drug use and diabetes.<\/p>\n
\u201cPatients with sepsis and cancer have lower [length of stay], higher-all cause mortality, and have no influence on readmission, bloodstream infection, and in-hospital mortality,\u201d the investigators concluded.<\/p>\n","protected":false},"excerpt":{"rendered":"iStock.com\/SDI Productions Patients with cancer who developed sepsis were more likely to have a \u201chigher association\u201d with various…\n","protected":false},"author":2,"featured_media":414088,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60],"class_list":{"0":"post-414087","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-health","8":"tag-health","9":"tag-ie","10":"tag-ireland"},"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/414087","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=414087"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/414087\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/414088"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=414087"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=414087"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=414087"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}