{"id":421826,"date":"2026-04-28T15:31:09","date_gmt":"2026-04-28T15:31:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/421826\/"},"modified":"2026-04-28T15:31:09","modified_gmt":"2026-04-28T15:31:09","slug":"stents-can-ease-symptoms-of-post-thrombotic-syndrome","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/421826\/","title":{"rendered":"Stents\u00a0Can\u00a0Ease Symptoms of Post-Thrombotic Syndrome\u00a0\u00a0"},"content":{"rendered":"

\"\"<\/a>Kush Desai, \u201807 MD, \u201912 GME, chief of Vascular and Interventional Radiology in the Department of Radiology, was a co-author of the clinical trial.<\/p>\n

A procedure to reopen blocked veins successfully reduces pain, swelling and disability in people with post-thrombotic syndrome \u2014 a common and often debilitating complication of deep vein thrombosis \u2014 according to results of a clinical trial published<\/a> in The New England Journal of Medicine.<\/p>\n

Post-thrombotic syndrome\u00a0develops in as many as half of patients after a deep\u00a0vein thrombosis, which occurs\u00a0when damage from\u00a0a\u00a0blood clot leaves\u00a0the\u00a0veins narrowed\/blocked\u00a0and inflamed. The condition can cause chronic leg pain, swelling, skin changes and ulcers that limit mobility and quality of life, said\u00a0Kush Desai, \u201807 MD, \u201912 GME<\/a>, chief of Vascular and Interventional Radiology in the\u00a0Department of Radiology<\/a>, who was a co-author of the current clinical trial.\u00a0<\/p>\n

\u201cThese patients suffer in silence,\u201d\u00a0Desai said.\u00a0\u201cIt\u2019s underdiagnosed,\u00a0or frankly, not diagnosed,\u00a0and we have had no\u00a0proven\u00a0way to treat it.\u201d\u00a0<\/p>\n

The new study\u00a0tested whether endovascular therapy\u00a0\u2014\u00a0placing a metal stent in the vein to restore blood flow, combined with enhanced antithrombotic treatment\u00a0\u2014\u00a0could improve outcomes for patients with moderate to severe\u00a0post\u2011thrombotic\u00a0syndrome and confirmed venous obstruction.\u00a0<\/p>\n

Investigators randomly assigned 225 patients to receive either endovascular therapy plus standard care or standard care alone, which includes compression therapy,\u00a0medications\u00a0and\u00a0lifestyle\u00a0changes. Symptom severity at six months was assessed using the Venous Clinical Severity Score.\u00a0<\/p>\n

At six months, patients who received endovascular therapy had significantly less severe symptoms than those who received standard care alone, according to the findings, and patients\u00a0treated with stents also reported better quality of life and better overall physical health\u00a0<\/p>\n

At the same time, the therapy was\u00a0also\u00a0associated with more complications. Through six months of\u00a0follow\u2011up, bleeding events occurred in\u00a0nearly 12 percent\u00a0of patients who underwent endovascular treatment, compared with about 4 percent of those who received standard care\u00a0alone.\u00a0<\/p>\n

Desai noted that patients that receive endovascular therapy need blood thinners,\u00a0whereas\u00a0those that receive standard care\u00a0frequently\u00a0do not. <\/p>\n

\u201cThis may be an explanation as to why bleeding occurred more frequently in those patients, and points to the need for providers to be aware of those risks,\u201d Desai said. <\/p>\n

\u201cThe standard of care for so long has been compression socks, blood thinners and medications that treat the symptoms, but don\u2019t really strike at the cause,\u201d\u00a0Desai\u00a0said. \u201cThe idea was: Does opening up that blockage with a stent give these patients an improvement not only in their symptoms, but their quality of life\u00a0\u2014\u00a0and does it do so safely?\u201d\u00a0<\/p>\n

While\u00a0the treatment is not\u00a0appropriate for\u00a0all patients with\u00a0post\u2011thrombotic\u00a0syndrome,\u00a0it may offer\u00a0an option\u00a0for carefully selected individuals with significant\u00a0large\u00a0vein obstruction and persistent symptoms, Desai said.\u00a0<\/p>\n

Beyond supporting a new treatment strategy,\u00a0Desai said\u00a0the study may improve recognition of a condition that\u00a0frequently\u00a0goes undiagnosed.\u00a0<\/p>\n

\u201cIf you don\u2019t recognize the disease, you don\u2019t know\u00a0which specialist\u00a0to refer\u00a0that patient\u00a0to,\u201d Desai said. \u201cNow physicians can recognize it, put a name to it and know there are specialists who focus on\u00a0post\u2011thrombotic\u00a0syndrome care.\u201d\u00a0<\/p>\n

Moving forward, Desai and his collaborators will continue\u00a0to analyze the trial data to better understand which patients benefit most from endovascular therapy.\u00a0Longer\u2011term\u00a0follow\u2011up\u00a0will also examine whether the symptom relief persists and how stents perform over time, he said.\u00a0<\/p>\n

\u201cWe\u2019ve always thought these patients had hope,\u201d Desai said. \u201cBut now we can say\u00a0they\u00a0do have hope.\u00a0We\u00a0actually have\u00a0an approach\u00a0that\u00a0we\u2019ve\u00a0proven works.\u201d\u00a0<\/p>\n

The study was funded by the National Heart, Lung, and Blood Institute.\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"Kush Desai, \u201807 MD, \u201912 GME, chief of Vascular and Interventional Radiology in the Department of Radiology, was…\n","protected":false},"author":2,"featured_media":421827,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60,10223,89],"class_list":["post-421826","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-ie","tag-ireland","tag-radiology","tag-research"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/421826","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=421826"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/421826\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/421827"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=421826"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=421826"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=421826"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}