{"id":487811,"date":"2026-06-07T17:12:08","date_gmt":"2026-06-07T17:12:08","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/487811\/"},"modified":"2026-06-07T17:12:08","modified_gmt":"2026-06-07T17:12:08","slug":"is-tchp-still-the-standard-new-data-reshaping-early-stage-her2-treatment","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/487811\/","title":{"rendered":"Is TCHP Still the Standard? New Data Reshaping Early-Stage HER2+ Treatment"},"content":{"rendered":"<p>In this first segment of a roundtable discussion with Paolo Tarantino, MD, PhD, Maryam Lustberg, MD, MPH, Margaret Gatti-Mays, MD, MPH, and Matthew Kurian, MD, we explore how the early-stage HER2-positive breast cancer landscape is rapidly evolving after new data from ASCO 2026 and ESMO Breast Cancer 2026. The panel discusses key data from DESTINY-Breast11 and emerging bispecific therapies like anbenitamab, questioning whether TCHP should remain the standard of care. The conversation highlights growing interest in de-escalation, alternative regimens like THP, and the need to better tailor treatment intensity based on patient risk, reflecting ongoing uncertainty and active debate in clinical practice.<\/p>\n","protected":false},"excerpt":{"rendered":"In this first segment of a roundtable discussion with Paolo Tarantino, MD, PhD, Maryam Lustberg, MD, MPH, Margaret&hellip;\n","protected":false},"author":2,"featured_media":487812,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[61,60,80],"class_list":["post-487811","post","type-post","status-publish","format-standard","has-post-thumbnail","category-technology","tag-ie","tag-ireland","tag-technology"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/487811","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=487811"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/487811\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/487812"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=487811"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=487811"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=487811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}