{"id":501583,"date":"2026-06-16T00:22:20","date_gmt":"2026-06-16T00:22:20","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/501583\/"},"modified":"2026-06-16T00:22:20","modified_gmt":"2026-06-16T00:22:20","slug":"neumora-ends-depression-drug-programme-and-announces-workforce-reduction-nmra","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/501583\/","title":{"rendered":"Neumora Ends Depression Drug Programme and Announces Workforce Reduction (NMRA)"},"content":{"rendered":"<p>    <img fetchpriority=\"high\" decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2026\/06\/659fa6e2e8050be7f271bfb96ab7cdb2.jpeg\" alt=\"medical research red syringe NEW SIZE \u00a9rawpixel\" loading=\"eager\" height=\"439\" width=\"800\" class=\"yf-lglytj  loaded\"\/> medical research red syringe NEW SIZE \u00a9rawpixel      <\/p>\n<p class=\"yf-1fy9kyt\">Neumora Therapeutics (NASDAQ:NMRA) said on Monday that it will halt development of its experimental depression treatment navacaprant after two Phase III clinical studies failed to meet their primary efficacy goals.<\/p>\n<p class=\"yf-1fy9kyt\">The drug candidate had been under evaluation as a potential treatment for patients suffering from major depressive disorder.<\/p>\n<p>         Late-Stage Trial Setbacks Prompt Strategic Review    <\/p>\n<p class=\"yf-1fy9kyt\">The decision follows disappointing results from the company\u2019s late-stage clinical programme, which was designed to assess the effectiveness of navacaprant in treating depression.<\/p>\n<p class=\"yf-1fy9kyt\">After reviewing the outcomes of the studies, management elected to discontinue further development of the therapy and redirect resources toward other priorities within its pipeline.<\/p>\n<p>      Company Implements Cost-Saving Measures    <\/p>\n<p class=\"yf-1fy9kyt\">Alongside the programme termination, Neumora announced plans to reduce its workforce by approximately 35% as part of a broader restructuring initiative aimed at lowering operating expenses.<\/p>\n<p class=\"yf-1fy9kyt\">The company expects the measures to deliver annual cost savings of around $10 million.<\/p>\n<p>      Restructuring Expected to Generate One-Time Charges    <\/p>\n<p class=\"yf-1fy9kyt\">Neumora said the workforce reduction will result in one-off restructuring expenses of approximately $2 million.<\/p>\n<p class=\"yf-1fy9kyt\">Management believes the cost-cutting programme will strengthen the company\u2019s financial position following the setback in its depression drug development efforts.<\/p>\n<p class=\"yf-1fy9kyt\">Neumora Therapeutics stock price<\/p>\n","protected":false},"excerpt":{"rendered":"medical research red syringe NEW SIZE \u00a9rawpixel Neumora Therapeutics (NASDAQ:NMRA) said on Monday that it will halt development&hellip;\n","protected":false},"author":2,"featured_media":501584,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[35],"tags":[102149,118841,103,61,60,44659,410,411,214552],"class_list":["post-501583","post","type-post","status-publish","format-standard","has-post-thumbnail","category-mental-health","tag-depression-treatment","tag-drug-candidate","tag-health","tag-ie","tag-ireland","tag-major-depressive-disorder","tag-mental-health","tag-mentalhealth","tag-neumora-therapeutics"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/501583","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=501583"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/501583\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/501584"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=501583"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=501583"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=501583"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}