{"id":520710,"date":"2026-06-27T05:19:31","date_gmt":"2026-06-27T05:19:31","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/520710\/"},"modified":"2026-06-27T05:19:31","modified_gmt":"2026-06-27T05:19:31","slug":"stepwise-emergence-of-recombination-suppression-precedes-fissiparous-asexuality-in-the-planarian-schmidtea-mediterranea","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/520710\/","title":{"rendered":"Stepwise emergence of recombination suppression precedes fissiparous asexuality in the planarian Schmidtea mediterranea"},"content":{"rendered":"<p class=\"c-article-references__text\" id=\"ref-CR1\">Otto, S. P. The Evolutionary Enigma of Sex. Am. Nat. 174, S1\u2013S14 (2009).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/599084\" data-track-item_id=\"10.1086\/599084\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F599084\" aria-label=\"Article reference 1\" data-doi=\"10.1086\/599084\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=19441962\" aria-label=\"PubMed reference 1\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 1\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20Evolutionary%20Enigma%20of%20Sex&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F599084&amp;volume=174&amp;pages=S1-S14&amp;publication_year=2009&amp;author=Otto%2CSP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR2\">Gibson, A. K., Delph, L. F. &amp; Lively, C. M. The two-fold cost of sex: Experimental evidence from a natural system. Evol. Lett. 1, 6\u201315 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/evl3.1\" data-track-item_id=\"10.1002\/evl3.1\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Fevl3.1\" aria-label=\"Article reference 2\" data-doi=\"10.1002\/evl3.1\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30233811\" aria-label=\"PubMed reference 2\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6089407\" aria-label=\"PubMed Central reference 2\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 2\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20two-fold%20cost%20of%20sex%3A%20Experimental%20evidence%20from%20a%20natural%20system&amp;journal=Evol.%20Lett.&amp;doi=10.1002%2Fevl3.1&amp;volume=1&amp;pages=6-15&amp;publication_year=2017&amp;author=Gibson%2CAK&amp;author=Delph%2CLF&amp;author=Lively%2CCM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR3\">Charlesworth, D., Barton, N. H. &amp; Charlesworth, B. The sources of adaptive variation. Proc. R. Soc. B Biol. Sci. 284, 20162864 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1098\/rspb.2016.2864\" data-track-item_id=\"10.1098\/rspb.2016.2864\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1098%2Frspb.2016.2864\" aria-label=\"Article reference 3\" data-doi=\"10.1098\/rspb.2016.2864\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 3\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20sources%20of%20adaptive%20variation&amp;journal=Proc.%20R.%20Soc.%20B%20Biol.%20Sci.&amp;doi=10.1098%2Frspb.2016.2864&amp;volume=284&amp;publication_year=2017&amp;author=Charlesworth%2CD&amp;author=Barton%2CNH&amp;author=Charlesworth%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR4\">Lehtonen, J., Jennions, M. D. &amp; Kokko, H. The many costs of sex. Trends Ecol. Evol. 27, 172\u2013178 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.tree.2011.09.016\" data-track-item_id=\"10.1016\/j.tree.2011.09.016\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.tree.2011.09.016\" aria-label=\"Article reference 4\" data-doi=\"10.1016\/j.tree.2011.09.016\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=22019414\" aria-label=\"PubMed reference 4\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 4\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20many%20costs%20of%20sex&amp;journal=Trends%20Ecol.%20Evol.&amp;doi=10.1016%2Fj.tree.2011.09.016&amp;volume=27&amp;pages=172-178&amp;publication_year=2012&amp;author=Lehtonen%2CJ&amp;author=Jennions%2CMD&amp;author=Kokko%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR5\">Hartfield, M. &amp; Keightley, P. D. Current hypotheses for the evolution of sex and recombination. Integr. Zool. 7, 192\u2013209 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1749-4877.2012.00284.x\" data-track-item_id=\"10.1111\/j.1749-4877.2012.00284.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1749-4877.2012.00284.x\" aria-label=\"Article reference 5\" data-doi=\"10.1111\/j.1749-4877.2012.00284.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=22691203\" aria-label=\"PubMed reference 5\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 5\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Current%20hypotheses%20for%20the%20evolution%20of%20sex%20and%20recombination&amp;journal=Integr.%20Zool.&amp;doi=10.1111%2Fj.1749-4877.2012.00284.x&amp;volume=7&amp;pages=192-209&amp;publication_year=2012&amp;author=Hartfield%2CM&amp;author=Keightley%2CPD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR6\">Scheu, S. &amp; Drossel, B. Sexual reproduction prevails in a world of structured resources in short supply. Proc. R. Soc. B Biol. Sci. 274, 1225\u20131231 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1098\/rspb.2007.0040\" data-track-item_id=\"10.1098\/rspb.2007.0040\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1098%2Frspb.2007.0040\" aria-label=\"Article reference 6\" data-doi=\"10.1098\/rspb.2007.0040\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DC%2BD2s3jsFSltg%3D%3D\" aria-label=\"CAS reference 6\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 6\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Sexual%20reproduction%20prevails%20in%20a%20world%20of%20structured%20resources%20in%20short%20supply&amp;journal=Proc.%20R.%20Soc.%20B%20Biol.%20Sci.&amp;doi=10.1098%2Frspb.2007.0040&amp;volume=274&amp;pages=1225-1231&amp;publication_year=2007&amp;author=Scheu%2CS&amp;author=Drossel%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR7\">Bell, G. The costs of reproduction and their consequences. Am. Nat. 116, 45\u201376 (1980).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/283611\" data-track-item_id=\"10.1086\/283611\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F283611\" aria-label=\"Article reference 7\" data-doi=\"10.1086\/283611\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 7\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20costs%20of%20reproduction%20and%20their%20consequences&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F283611&amp;volume=116&amp;pages=45-76&amp;publication_year=1980&amp;author=Bell%2CG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR8\">Van Valen, L. A new evolutionary law. Evol. Theory 1, 1\u201330 (1973).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 8\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20new%20evolutionary%20law&amp;journal=Evol.%20Theory&amp;volume=1&amp;pages=1-30&amp;publication_year=1973&amp;author=Valen%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR9\">Jaenike, J. A hypothesis to account for the maintenance of sex in populations. Evol Theory 3, 191\u2013194 (1978).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 9\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20hypothesis%20to%20account%20for%20the%20maintenance%20of%20sex%20in%20populations&amp;journal=Evol%20Theory&amp;volume=3&amp;pages=191-194&amp;publication_year=1978&amp;author=Jaenike%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR10\">Hill, W. G. &amp; Robertson, A. The effect of linkage on limits to artificial selection. Genet. Res. 8, 269\u2013294 (1966).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1017\/S0016672300010156\" data-track-item_id=\"10.1017\/S0016672300010156\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1017%2FS0016672300010156\" aria-label=\"Article reference 10\" data-doi=\"10.1017\/S0016672300010156\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaF2s3kvFyguw%3D%3D\" aria-label=\"CAS reference 10\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=5980116\" aria-label=\"PubMed reference 10\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 10\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20effect%20of%20linkage%20on%20limits%20to%20artificial%20selection&amp;journal=Genet.%20Res.&amp;doi=10.1017%2FS0016672300010156&amp;volume=8&amp;pages=269-294&amp;publication_year=1966&amp;author=Hill%2CWG&amp;author=Robertson%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR11\">Muller, H. J. Some genetic aspects of sex. Am. Nat. 66, 118\u2013138 (1932).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/280418\" data-track-item_id=\"10.1086\/280418\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F280418\" aria-label=\"Article reference 11\" data-doi=\"10.1086\/280418\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 11\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Some%20genetic%20aspects%20of%20sex&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F280418&amp;volume=66&amp;pages=118-138&amp;publication_year=1932&amp;author=Muller%2CHJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR12\">Crow, J. F. &amp; Kimura, M. Evolution in sexual and asexual populations. Am. Nat. 99, 439\u2013450 (1965).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1086\/282389\" data-track-item_id=\"10.1086\/282389\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1086%2F282389\" aria-label=\"Article reference 12\" data-doi=\"10.1086\/282389\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 12\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evolution%20in%20sexual%20and%20asexual%20populations&amp;journal=Am.%20Nat.&amp;doi=10.1086%2F282389&amp;volume=99&amp;pages=439-450&amp;publication_year=1965&amp;author=Crow%2CJF&amp;author=Kimura%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR13\">Barraclough, T. G., Fontaneto, D., Ricci, C. &amp; Herniou, E. A. Evidence for inefficient selection against deleterious mutations in cytochrome oxidase I of asexual bdelloid rotifers. Mol. Biol. Evol. 24, 1952\u20131962 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msm123\" data-track-item_id=\"10.1093\/molbev\/msm123\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsm123\" aria-label=\"Article reference 13\" data-doi=\"10.1093\/molbev\/msm123\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXhtFSjsLbI\" aria-label=\"CAS reference 13\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17573376\" aria-label=\"PubMed reference 13\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 13\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evidence%20for%20inefficient%20selection%20against%20deleterious%20mutations%20in%20cytochrome%20oxidase%20I%20of%20asexual%20bdelloid%20rotifers&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsm123&amp;volume=24&amp;pages=1952-1962&amp;publication_year=2007&amp;author=Barraclough%2CTG&amp;author=Fontaneto%2CD&amp;author=Ricci%2CC&amp;author=Herniou%2CEA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR14\">Johnson, S. G. &amp; Howard, R. S. Contrasting patterns of synonymous and nonsynonymous sequence evolution in asexual and sexual freshwater snail lineages. Evolution 61, 2728\u20132735 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1558-5646.2007.00233.x\" data-track-item_id=\"10.1111\/j.1558-5646.2007.00233.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1558-5646.2007.00233.x\" aria-label=\"Article reference 14\" data-doi=\"10.1111\/j.1558-5646.2007.00233.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17908244\" aria-label=\"PubMed reference 14\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 14\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Contrasting%20patterns%20of%20synonymous%20and%20nonsynonymous%20sequence%20evolution%20in%20asexual%20and%20sexual%20freshwater%20snail%20lineages&amp;journal=Evolution&amp;doi=10.1111%2Fj.1558-5646.2007.00233.x&amp;volume=61&amp;pages=2728-2735&amp;publication_year=2007&amp;author=Johnson%2CSG&amp;author=Howard%2CRS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR15\">Neiman, M., Hehman, G., Miller, J. T., Logsdon, J. M. &amp; Taylor, D. R. Accelerated mutation accumulation in asexual lineages of a freshwater snail. Mol. Biol. Evol. 27, 954\u2013963 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msp300\" data-track-item_id=\"10.1093\/molbev\/msp300\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsp300\" aria-label=\"Article reference 15\" data-doi=\"10.1093\/molbev\/msp300\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3cXjslals7k%3D\" aria-label=\"CAS reference 15\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=19995828\" aria-label=\"PubMed reference 15\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 15\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Accelerated%20mutation%20accumulation%20in%20asexual%20lineages%20of%20a%20freshwater%20snail&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsp300&amp;volume=27&amp;pages=954-963&amp;publication_year=2010&amp;author=Neiman%2CM&amp;author=Hehman%2CG&amp;author=Miller%2CJT&amp;author=Logsdon%2CJM&amp;author=Taylor%2CDR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR16\">Henry, L., Schwander, T. &amp; Crespi, B. J. Deleterious mutation accumulation in asexual Timema stick insects. Mol. Biol. Evol. 29, 401\u2013408 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msr237\" data-track-item_id=\"10.1093\/molbev\/msr237\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsr237\" aria-label=\"Article reference 16\" data-doi=\"10.1093\/molbev\/msr237\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3MXhs1ynurzM\" aria-label=\"CAS reference 16\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=21940645\" aria-label=\"PubMed reference 16\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 16\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Deleterious%20mutation%20accumulation%20in%20asexual%20Timema%20stick%20insects&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsr237&amp;volume=29&amp;pages=401-408&amp;publication_year=2012&amp;author=Henry%2CL&amp;author=Schwander%2CT&amp;author=Crespi%2CBJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR17\">Hersch-Green, E. I., Myburg, H. &amp; Johnson, M. T. J. Adaptive molecular evolution of a defence gene in sexual but not functionally asexual evening primroses: Plant sex and molecular evolution in defence. J. Evol. Biol. 25, 1576\u20131586 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1420-9101.2012.02542.x\" data-track-item_id=\"10.1111\/j.1420-9101.2012.02542.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1420-9101.2012.02542.x\" aria-label=\"Article reference 17\" data-doi=\"10.1111\/j.1420-9101.2012.02542.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC38XhtFOnurzP\" aria-label=\"CAS reference 17\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=22587337\" aria-label=\"PubMed reference 17\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 17\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Adaptive%20molecular%20evolution%20of%20a%20defence%20gene%20in%20sexual%20but%20not%20functionally%20asexual%20evening%20primroses%3A%20Plant%20sex%20and%20molecular%20evolution%20in%20defence&amp;journal=J.%20Evol.%20Biol.&amp;doi=10.1111%2Fj.1420-9101.2012.02542.x&amp;volume=25&amp;pages=1576-1586&amp;publication_year=2012&amp;author=Hersch-Green%2CEI&amp;author=Myburg%2CH&amp;author=Johnson%2CMTJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR18\">Hollister, J. D. et al. Recurrent loss of sex is associated with accumulation of deleterious mutations in Oenothera. Mol. Biol. Evol. 32, 896\u2013905 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msu345\" data-track-item_id=\"10.1093\/molbev\/msu345\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsu345\" aria-label=\"Article reference 18\" data-doi=\"10.1093\/molbev\/msu345\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC28XhtlWnurbN\" aria-label=\"CAS reference 18\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25534028\" aria-label=\"PubMed reference 18\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 18\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Recurrent%20loss%20of%20sex%20is%20associated%20with%20accumulation%20of%20deleterious%20mutations%20in%20Oenothera&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsu345&amp;volume=32&amp;pages=896-905&amp;publication_year=2015&amp;author=Hollister%2CJD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR19\">Bast, J. et al. Consequences of asexuality in natural populations: insights from stick insects. Mol. Biol. Evol. 35, 1668\u20131677 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msy058\" data-track-item_id=\"10.1093\/molbev\/msy058\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsy058\" aria-label=\"Article reference 19\" data-doi=\"10.1093\/molbev\/msy058\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXhtF2rur7P\" aria-label=\"CAS reference 19\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29659991\" aria-label=\"PubMed reference 19\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5995167\" aria-label=\"PubMed Central reference 19\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 19\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Consequences%20of%20asexuality%20in%20natural%20populations%3A%20insights%20from%20stick%20insects&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsy058&amp;volume=35&amp;pages=1668-1677&amp;publication_year=2018&amp;author=Bast%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR20\">Ament-Vel\u00e1squez, S. L. et al. Population genomics of sexual and asexual lineages in fissiparous ribbon worms (Lineus, Nemertea): hybridization, polyploidy and the Meselson effect. Mol. Ecol. 25, 3356\u20133369 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/mec.13717\" data-track-item_id=\"10.1111\/mec.13717\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fmec.13717\" aria-label=\"Article reference 20\" data-doi=\"10.1111\/mec.13717\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27286413\" aria-label=\"PubMed reference 20\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 20\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Population%20genomics%20of%20sexual%20and%20asexual%20lineages%20in%20fissiparous%20ribbon%20worms%20%28Lineus%2C%20Nemertea%29%3A%20hybridization%2C%20polyploidy%20and%20the%20Meselson%20effect&amp;journal=Mol.%20Ecol.&amp;doi=10.1111%2Fmec.13717&amp;volume=25&amp;pages=3356-3369&amp;publication_year=2016&amp;author=Ament-Vel%C3%A1squez%2CSL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR21\">Brandt, A. et al. Effective purifying selection in ancient asexual oribatid mites. Nat. Commun. 8, 873 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-017-01002-8\" data-track-item_id=\"10.1038\/s41467-017-01002-8\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-017-01002-8\" aria-label=\"Article reference 21\" data-doi=\"10.1038\/s41467-017-01002-8\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2017NatCo...8..873B\" aria-label=\"ADS reference 21\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29026136\" aria-label=\"PubMed reference 21\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5638860\" aria-label=\"PubMed Central reference 21\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 21\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Effective%20purifying%20selection%20in%20ancient%20asexual%20oribatid%20mites&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-017-01002-8&amp;volume=8&amp;publication_year=2017&amp;author=Brandt%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR22\">Brandt, A. et al. No signal of deleterious mutation accumulation in conserved gene sequences of extant asexual hexapods. Sci. Rep. 9, 5338 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41598-019-41821-x\" data-track-item_id=\"10.1038\/s41598-019-41821-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41598-019-41821-x\" aria-label=\"Article reference 22\" data-doi=\"10.1038\/s41598-019-41821-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2019NatSR...9.5338B\" aria-label=\"ADS reference 22\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30926861\" aria-label=\"PubMed reference 22\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6441085\" aria-label=\"PubMed Central reference 22\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 22\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=No%20signal%20of%20deleterious%20mutation%20accumulation%20in%20conserved%20gene%20sequences%20of%20extant%20asexual%20hexapods&amp;journal=Sci.%20Rep.&amp;doi=10.1038%2Fs41598-019-41821-x&amp;volume=9&amp;publication_year=2019&amp;author=Brandt%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR23\">Warren, W. C. et al. Clonal polymorphism and high heterozygosity in the celibate genome of the Amazon molly. Nat. Ecol. Evol. 2, 669\u2013679 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41559-018-0473-y\" data-track-item_id=\"10.1038\/s41559-018-0473-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41559-018-0473-y\" aria-label=\"Article reference 23\" data-doi=\"10.1038\/s41559-018-0473-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29434351\" aria-label=\"PubMed reference 23\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5866774\" aria-label=\"PubMed Central reference 23\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 23\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Clonal%20polymorphism%20and%20high%20heterozygosity%20in%20the%20celibate%20genome%20of%20the%20Amazon%20molly&amp;journal=Nat.%20Ecol.%20Evol.&amp;doi=10.1038%2Fs41559-018-0473-y&amp;volume=2&amp;pages=669-679&amp;publication_year=2018&amp;author=Warren%2CWC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR24\">Howe, J., Rink, J. C., Wang, B. &amp; Griffin, A. S. Multicellularity in animals: the potential for within-organism conflict. Proc. Natl. Acad. Sci. USA. 119, e2120457119 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.2120457119\" data-track-item_id=\"10.1073\/pnas.2120457119\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.2120457119\" aria-label=\"Article reference 24\" data-doi=\"10.1073\/pnas.2120457119\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38Xit1antLnJ\" aria-label=\"CAS reference 24\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35862435\" aria-label=\"PubMed reference 24\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9371690\" aria-label=\"PubMed Central reference 24\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 24\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Multicellularity%20in%20animals%3A%20the%20potential%20for%20within-organism%20conflict&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.2120457119&amp;volume=119&amp;publication_year=2022&amp;author=Howe%2CJ&amp;author=Rink%2CJC&amp;author=Wang%2CB&amp;author=Griffin%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR25\">Otto, S. P. &amp; Orive, M. E. Evolutionary consequences of mutation and selection within an individual. Genetics 141, 1173\u20131187 (1995).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/genetics\/141.3.1173\" data-track-item_id=\"10.1093\/genetics\/141.3.1173\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgenetics%2F141.3.1173\" aria-label=\"Article reference 25\" data-doi=\"10.1093\/genetics\/141.3.1173\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaK287ivFaqsg%3D%3D\" aria-label=\"CAS reference 25\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=8582622\" aria-label=\"PubMed reference 25\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1206839\" aria-label=\"PubMed Central reference 25\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 25\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evolutionary%20consequences%20of%20mutation%20and%20selection%20within%20an%20individual&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2F141.3.1173&amp;volume=141&amp;pages=1173-1187&amp;publication_year=1995&amp;author=Otto%2CSP&amp;author=Orive%2CME\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR26\">Leria, L., Vila-Farr\u00e9, M., Sola, E. &amp; Riutort, M. Outstanding intraindividual genetic diversity in fissiparous planarians (Dugesia, Platyhelminthes) with facultative sex. BMC Evol. Biol. 19, 130\u2013130 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12862-019-1440-1\" data-track-item_id=\"10.1186\/s12862-019-1440-1\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12862-019-1440-1\" aria-label=\"Article reference 26\" data-doi=\"10.1186\/s12862-019-1440-1\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31221097\" aria-label=\"PubMed reference 26\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6587288\" aria-label=\"PubMed Central reference 26\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 26\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Outstanding%20intraindividual%20genetic%20diversity%20in%20fissiparous%20planarians%20%28Dugesia%2C%20Platyhelminthes%29%20with%20facultative%20sex&amp;journal=BMC%20Evol.%20Biol.&amp;doi=10.1186%2Fs12862-019-1440-1&amp;volume=19&amp;pages=130-130&amp;publication_year=2019&amp;author=Leria%2CL&amp;author=Vila-Farr%C3%A9%2CM&amp;author=Sola%2CE&amp;author=Riutort%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR27\">Otto, S. P. &amp; Hastings, I. M. Mutation and selection within the individual. Genetica 102\u2013103, 507\u2013524 (1998).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1023\/A:1017074823337\" data-track-item_id=\"10.1023\/A:1017074823337\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1023%2FA%3A1017074823337\" aria-label=\"Article reference 27\" data-doi=\"10.1023\/A:1017074823337\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=9766963\" aria-label=\"PubMed reference 27\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 27\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mutation%20and%20selection%20within%20the%20individual&amp;journal=Genetica&amp;doi=10.1023%2FA%3A1017074823337&amp;volume=102%E2%80%93103&amp;pages=507-524&amp;publication_year=1998&amp;author=Otto%2CSP&amp;author=Hastings%2CIM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR28\">Vila-Farr\u00e9, M. &amp; C. Rink, J. The ecology of freshwater planarians. In Planarian Regeneration: Methods and Protocols (eds Rink, J. C.) 173\u2013205 (Springer, 2018).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR29\">Ivankovic, M. et al. Model systems for regeneration: planarians. Dev. Camb. Engl. 146, dev167684 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXit1Gju7%2FO\" aria-label=\"CAS reference 29\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 29\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Model%20systems%20for%20regeneration%3A%20planarians&amp;journal=Dev.%20Camb.%20Engl.&amp;volume=146&amp;publication_year=2019&amp;author=Ivankovic%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR30\">Reddien, P. W. The cellular and molecular basis for planarian regeneration. Cell 175, 327\u2013345 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cell.2018.09.021\" data-track-item_id=\"10.1016\/j.cell.2018.09.021\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cell.2018.09.021\" aria-label=\"Article reference 30\" data-doi=\"10.1016\/j.cell.2018.09.021\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXhvVKnu7zP\" aria-label=\"CAS reference 30\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30290140\" aria-label=\"PubMed reference 30\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7706840\" aria-label=\"PubMed Central reference 30\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 30\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20cellular%20and%20molecular%20basis%20for%20planarian%20regeneration&amp;journal=Cell&amp;doi=10.1016%2Fj.cell.2018.09.021&amp;volume=175&amp;pages=327-345&amp;publication_year=2018&amp;author=Reddien%2CPW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR31\">Oviedo, N. J., Nicolas, C. L., Adams, D. S. &amp; Levin, M. Planarians: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging, and behavior. CSH Protoc. 2008, pdb.emo101 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=21356684\" aria-label=\"PubMed reference 31\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10467510\" aria-label=\"PubMed Central reference 31\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 31\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Planarians%3A%20a%20versatile%20and%20powerful%20model%20system%20for%20molecular%20studies%20of%20regeneration%2C%20adult%20stem%20cell%20regulation%2C%20aging%2C%20and%20behavior&amp;journal=CSH%20Protoc.&amp;volume=2008&amp;publication_year=2008&amp;author=Oviedo%2CNJ&amp;author=Nicolas%2CCL&amp;author=Adams%2CDS&amp;author=Levin%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR32\">S\u00e1nchez Alvarado, A., Newmark, P. A., Robb, S. M. &amp; Juste, R. The Schmidtea mediterranea database as a molecular resource for studying platyhelminthes, stem cells and regeneration. Dev. Camb. Engl. 129, 5659\u20135665 (2002).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 32\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20Schmidtea%20mediterranea%20database%20as%20a%20molecular%20resource%20for%20studying%20platyhelminthes%2C%20stem%20cells%20and%20regeneration&amp;journal=Dev.%20Camb.%20Engl.&amp;volume=129&amp;pages=5659-5665&amp;publication_year=2002&amp;author=S%C3%A1nchez%20Alvarado%2CA&amp;author=Newmark%2CPA&amp;author=Robb%2CSM&amp;author=Juste%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR33\">Alvarado, A. S. Planarian regeneration: its end is its beginning. Cell 124, 241\u2013245 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cell.2006.01.012\" data-track-item_id=\"10.1016\/j.cell.2006.01.012\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cell.2006.01.012\" aria-label=\"Article reference 33\" data-doi=\"10.1016\/j.cell.2006.01.012\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 33\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Planarian%20regeneration%3A%20its%20end%20is%20its%20beginning&amp;journal=Cell&amp;doi=10.1016%2Fj.cell.2006.01.012&amp;volume=124&amp;pages=241-245&amp;publication_year=2006&amp;author=Alvarado%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR34\">Newmark, P. A. &amp; Alvarado, A. S. Not your father\u2019s planarian: a classic model enters the era of functional genomics. Nat. Rev. Genet. 3, 210\u2013219 (2002).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nrg759\" data-track-item_id=\"10.1038\/nrg759\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnrg759\" aria-label=\"Article reference 34\" data-doi=\"10.1038\/nrg759\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD38Xit1Cks7s%3D\" aria-label=\"CAS reference 34\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=11972158\" aria-label=\"PubMed reference 34\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 34\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Not%20your%20father%E2%80%99s%20planarian%3A%20a%20classic%20model%20enters%20the%20era%20of%20functional%20genomics&amp;journal=Nat.%20Rev.%20Genet.&amp;doi=10.1038%2Fnrg759&amp;volume=3&amp;pages=210-219&amp;publication_year=2002&amp;author=Newmark%2CPA&amp;author=Alvarado%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR35\">Alvarado, A. S. The freshwater planarian Schmidtea mediterranea: embryogenesis, stem cells and regeneration. Curr. Opin. Genet. Dev. 13, 438\u2013444 (2003).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/S0959-437X(03)00082-0\" data-track-item_id=\"10.1016\/S0959-437X(03)00082-0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2FS0959-437X%2803%2900082-0\" aria-label=\"Article reference 35\" data-doi=\"10.1016\/S0959-437X(03)00082-0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD3sXlvVGjsb8%3D\" aria-label=\"CAS reference 35\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 35\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20freshwater%20planarian%20Schmidtea%20mediterranea%3A%20embryogenesis%2C%20stem%20cells%20and%20regeneration&amp;journal=Curr.%20Opin.%20Genet.%20Dev.&amp;doi=10.1016%2FS0959-437X%2803%2900082-0&amp;volume=13&amp;pages=438-444&amp;publication_year=2003&amp;author=Alvarado%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR36\">Benazzi, M., Ballester, R., Bagu\u00f1\u00e1, J. &amp; Puccinelli, I. The fissiparous race of the planarian Dugesia lugubris s.l. found in Barcelona (Spain) belongs to the biotype G: comparative analysis of the karyotypes. Caryologia 25, 59\u201368 (1972).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/00087114.1972.10796465\" data-track-item_id=\"10.1080\/00087114.1972.10796465\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F00087114.1972.10796465\" aria-label=\"Article reference 36\" data-doi=\"10.1080\/00087114.1972.10796465\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 36\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20fissiparous%20race%20of%20the%20planarian%20Dugesia%20lugubris%20s.l.%20found%20in%20Barcelona%20%28Spain%29%20belongs%20to%20the%20biotype%20G%3A%20comparative%20analysis%20of%20the%20karyotypes&amp;journal=Caryologia&amp;doi=10.1080%2F00087114.1972.10796465&amp;volume=25&amp;pages=59-68&amp;publication_year=1972&amp;author=Benazzi%2CM&amp;author=Ballester%2CR&amp;author=Bagu%C3%B1%C3%A1%2CJ&amp;author=Puccinelli%2CI\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR37\">Bagu\u00f1\u00e0, J. et al. From morphology and karyology to molecules. New methods for taxonomical identification of asexual populations of freshwater planarians. A tribute to Professor Mario Benazzi. Ital. J. Zool. 66, 207\u2013214 (1999).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/11250009909356258\" data-track-item_id=\"10.1080\/11250009909356258\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F11250009909356258\" aria-label=\"Article reference 37\" data-doi=\"10.1080\/11250009909356258\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 37\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=From%20morphology%20and%20karyology%20to%20molecules.%20New%20methods%20for%20taxonomical%20identification%20of%20asexual%20populations%20of%20freshwater%20planarians.%20A%20tribute%20to%20Professor%20Mario%20Benazzi&amp;journal=Ital.%20J.%20Zool.&amp;doi=10.1080%2F11250009909356258&amp;volume=66&amp;pages=207-214&amp;publication_year=1999&amp;author=Bagu%C3%B1%C3%A0%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR38\">De Vries, E. J., Bagu\u00f1\u00e0, J. &amp; Ball, I. R. Chromosomal polymorphism in planarians (Turbellaria, Tricladida) and the plate tectonics of the western Mediterranean. Genetica 62, 187\u2013191 (1984).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/BF00056435\" data-track-item_id=\"10.1007\/BF00056435\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/BF00056435\" aria-label=\"Article reference 38\" data-doi=\"10.1007\/BF00056435\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 38\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Chromosomal%20polymorphism%20in%20planarians%20%28Turbellaria%2C%20Tricladida%29%20and%20the%20plate%20tectonics%20of%20the%20western%20Mediterranean&amp;journal=Genetica&amp;doi=10.1007%2FBF00056435&amp;volume=62&amp;pages=187-191&amp;publication_year=1984&amp;author=Vries%2CEJ&amp;author=Bagu%C3%B1%C3%A0%2CJ&amp;author=Ball%2CIR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR39\">L\u00e1zaro, E. M. et al. Schmidtea mediterranea phylogeography: an old species surviving on a few Mediterranean islands? BMC Evol. Biol. 11, 274 (2011).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2148-11-274\" data-track-item_id=\"10.1186\/1471-2148-11-274\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2148-11-274\" aria-label=\"Article reference 39\" data-doi=\"10.1186\/1471-2148-11-274\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=21943163\" aria-label=\"PubMed reference 39\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3203090\" aria-label=\"PubMed Central reference 39\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 39\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Schmidtea%20mediterranea%20phylogeography%3A%20an%20old%20species%20surviving%20on%20a%20few%20Mediterranean%20islands%3F&amp;journal=BMC%20Evol.%20Biol.&amp;doi=10.1186%2F1471-2148-11-274&amp;volume=11&amp;publication_year=2011&amp;author=L%C3%A1zaro%2CEM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR40\">Ribas, M. Cariologia, sistem\u00e0tica i biogeografia de les Plan\u00e0ries d\u2019aig\u00fces dolees als Pa\u00efsos Catalans. University of Barcelona (1990).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR41\">Harrath, A. H., Charni, M., Sluys, R., Zghal, F. &amp; Tekaya, S. Ecology and distribution of the freshwater planarian Schmidtea mediterranea in Tunisia. Ital. J. Zool. 71, 233\u2013236 (2004).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/11250000409356577\" data-track-item_id=\"10.1080\/11250000409356577\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F11250000409356577\" aria-label=\"Article reference 41\" data-doi=\"10.1080\/11250000409356577\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 41\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Ecology%20and%20distribution%20of%20the%20freshwater%20planarian%20Schmidtea%20mediterranea%20in%20Tunisia&amp;journal=Ital.%20J.%20Zool.&amp;doi=10.1080%2F11250000409356577&amp;volume=71&amp;pages=233-236&amp;publication_year=2004&amp;author=Harrath%2CAH&amp;author=Charni%2CM&amp;author=Sluys%2CR&amp;author=Zghal%2CF&amp;author=Tekaya%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR42\">Casu, S., Pala, M. &amp; Vacca, R. osa Alba. Distribuzione geografica in Sardegna di planarie d\u2019acqua dolce appartenenti alla specie \u201cDugesia (S.) polychroa\u201d e \u201cDugesia (S.) mediterranea\u201d. Boll. Soc. Sarda Sci. Nat. 21, 177\u2013184 (1982).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 42\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Alba.%20Distribuzione%20geografica%20in%20Sardegna%20di%20planarie%20d%E2%80%99acqua%20dolce%20appartenenti%20alla%20specie%20%E2%80%9CDugesia%20%28S.%29%20polychroa%E2%80%9D%20e%20%E2%80%9CDugesia%20%28S.%29%20mediterranea%E2%80%9D&amp;journal=Boll.%20Soc.%20Sarda%20Sci.%20Nat.&amp;volume=21&amp;pages=177-184&amp;publication_year=1982&amp;author=Casu%2CS&amp;author=Pala%2CM&amp;author=Vacca%2CRosa\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR43\">Guo, L., Zhang, S., Rubinstein, B., Ross, E. &amp; Alvarado, A. S. Widespread maintenance of genome heterozygosity in Schmidtea mediterranea. Nat. Ecol. Evol. 1, 1\u201310 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41559-016-0019\" data-track-item_id=\"10.1038\/s41559-016-0019\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41559-016-0019\" aria-label=\"Article reference 43\" data-doi=\"10.1038\/s41559-016-0019\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 43\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Widespread%20maintenance%20of%20genome%20heterozygosity%20in%20Schmidtea%20mediterranea&amp;journal=Nat.%20Ecol.%20Evol.&amp;doi=10.1038%2Fs41559-016-0019&amp;volume=1&amp;pages=1-10&amp;publication_year=2016&amp;author=Guo%2CL&amp;author=Zhang%2CS&amp;author=Rubinstein%2CB&amp;author=Ross%2CE&amp;author=Alvarado%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR44\">Leria, L., Sluys, R. &amp; Riutort, M. Diversification and biogeographic history of the Western Palearctic freshwater flatworm genus Schmidtea (Tricladida: Dugesiidae), with a redescription of Schmidtea nova. J. Zool. Syst. Evol. Res. 56, 335\u2013351 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/jzs.12214\" data-track-item_id=\"10.1111\/jzs.12214\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fjzs.12214\" aria-label=\"Article reference 44\" data-doi=\"10.1111\/jzs.12214\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 44\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Diversification%20and%20biogeographic%20history%20of%20the%20Western%20Palearctic%20freshwater%20flatworm%20genus%20Schmidtea%20%28Tricladida%3A%20Dugesiidae%29%2C%20with%20a%20redescription%20of%20Schmidtea%20nova&amp;journal=J.%20Zool.%20Syst.%20Evol.%20Res.&amp;doi=10.1111%2Fjzs.12214&amp;volume=56&amp;pages=335-351&amp;publication_year=2018&amp;author=Leria%2CL&amp;author=Sluys%2CR&amp;author=Riutort%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR45\">Ball, I. R. A contribution to the phylogeny and biogeography of the freshwater triclads (Platyhelminthes, Turbellaria). In The Hyman Memorial Volume\u2014Biology of the Turbellaria (eds Riser, N. W. &amp; Morse, M. P.) 339\u2013401 (McGraw-Hill, 1974).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR46\">De Baets, K., Dentzien-Dias, P., Upeniece, I., Verneau, O. &amp; Donoghue, P. C. J. Constraining the deep origin of parasitic flatworms and host-interactions with fossil evidence. in Advances in Parasitology (eds Littlewood, D. T. J. &amp; de Baets, K.) Vol. 90, 93\u2013135 (Elsevier, 2015).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR47\">Grohme, M. A. et al. The genome of Schmidtea mediterranea and the evolution of core cellular mechanisms. Nature 554, 56\u201361 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nature25473\" data-track-item_id=\"10.1038\/nature25473\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnature25473\" aria-label=\"Article reference 47\" data-doi=\"10.1038\/nature25473\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2018Natur.554...56G\" aria-label=\"ADS reference 47\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXhs12gsb4%3D\" aria-label=\"CAS reference 47\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29364871\" aria-label=\"PubMed reference 47\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5797480\" aria-label=\"PubMed Central reference 47\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 47\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20genome%20of%20Schmidtea%20mediterranea%20and%20the%20evolution%20of%20core%20cellular%20mechanisms&amp;journal=Nature&amp;doi=10.1038%2Fnature25473&amp;volume=554&amp;pages=56-61&amp;publication_year=2018&amp;author=Grohme%2CMA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR48\">Ivankovi\u0107, M. et al. A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence. Nat. Commun. 15, 8215 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41467-024-52380-9\" data-track-item_id=\"10.1038\/s41467-024-52380-9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41467-024-52380-9\" aria-label=\"Article reference 48\" data-doi=\"10.1038\/s41467-024-52380-9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2024NatCo..15.8215I\" aria-label=\"ADS reference 48\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=39294119\" aria-label=\"PubMed reference 48\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11410931\" aria-label=\"PubMed Central reference 48\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 48\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20comparative%20analysis%20of%20planarian%20genomes%20reveals%20regulatory%20conservation%20in%20the%20face%20of%20rapid%20structural%20divergence&amp;journal=Nat.%20Commun.&amp;doi=10.1038%2Fs41467-024-52380-9&amp;volume=15&amp;publication_year=2024&amp;author=Ivankovi%C4%87%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR49\">P\u00f3ti, \u00c1., Sz\u00fcts, D. &amp; Vermezovic, J. Mutational profile of the regenerative process and de novo genome assembly of the planarian Schmidtea polychroa. Nucleic Acids Res. <a href=\"https:\/\/doi.org\/10.1093\/nar\/gkad1250\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/nar\/gkad1250\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/nar\/gkad1250<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR50\">Tian, Q. et al. Whole-genome sequence of the planarian Dugesia japonica combining Illumina and PacBio data. Genomics 114, 110293 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.ygeno.2022.110293\" data-track-item_id=\"10.1016\/j.ygeno.2022.110293\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.ygeno.2022.110293\" aria-label=\"Article reference 50\" data-doi=\"10.1016\/j.ygeno.2022.110293\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XjsFOku7o%3D\" aria-label=\"CAS reference 50\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35139429\" aria-label=\"PubMed reference 50\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 50\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Whole-genome%20sequence%20of%20the%20planarian%20Dugesia%20japonica%20combining%20Illumina%20and%20PacBio%20data&amp;journal=Genomics&amp;doi=10.1016%2Fj.ygeno.2022.110293&amp;volume=114&amp;publication_year=2022&amp;author=Tian%2CQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR51\">An, Y. et al. Draft genome of Dugesia japonica provides insights into conserved regulatory elements of the brain restriction gene nou-darake in planarians. Zool. Lett. 4, 24 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s40851-018-0102-2\" data-track-item_id=\"10.1186\/s40851-018-0102-2\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s40851-018-0102-2\" aria-label=\"Article reference 51\" data-doi=\"10.1186\/s40851-018-0102-2\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 51\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Draft%20genome%20of%20Dugesia%20japonica%20provides%20insights%20into%20conserved%20regulatory%20elements%20of%20the%20brain%20restriction%20gene%20nou-darake%20in%20planarians&amp;journal=Zool.%20Lett.&amp;doi=10.1186%2Fs40851-018-0102-2&amp;volume=4&amp;publication_year=2018&amp;author=An%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR52\">Guo, L. et al. Island-specific evolution of a sex-primed autosome in a sexual planarian. Nature 606, 329\u2013334 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41586-022-04757-3\" data-track-item_id=\"10.1038\/s41586-022-04757-3\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41586-022-04757-3\" aria-label=\"Article reference 52\" data-doi=\"10.1038\/s41586-022-04757-3\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2022Natur.606..329G\" aria-label=\"ADS reference 52\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XhsVant7nP\" aria-label=\"CAS reference 52\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35650439\" aria-label=\"PubMed reference 52\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9177419\" aria-label=\"PubMed Central reference 52\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 52\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Island-specific%20evolution%20of%20a%20sex-primed%20autosome%20in%20a%20sexual%20planarian&amp;journal=Nature&amp;doi=10.1038%2Fs41586-022-04757-3&amp;volume=606&amp;pages=329-334&amp;publication_year=2022&amp;author=Guo%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR53\">Hoencamp, C. et al. 3D genomics across the tree of life reveals condensin II as a determinant of architecture type. Science 372, 984\u2013989 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.abe2218\" data-track-item_id=\"10.1126\/science.abe2218\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.abe2218\" aria-label=\"Article reference 53\" data-doi=\"10.1126\/science.abe2218\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXht1WrsLrK\" aria-label=\"CAS reference 53\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34045355\" aria-label=\"PubMed reference 53\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8172041\" aria-label=\"PubMed Central reference 53\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 53\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=3D%20genomics%20across%20the%20tree%20of%20life%20reveals%20condensin%20II%20as%20a%20determinant%20of%20architecture%20type&amp;journal=Science&amp;doi=10.1126%2Fscience.abe2218&amp;volume=372&amp;pages=984-989&amp;publication_year=2021&amp;author=Hoencamp%2CC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR54\">Kirilenko, B. M. et al. Integrating gene annotation with orthology inference at scale. Science 380, eabn3107 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1126\/science.abn3107\" data-track-item_id=\"10.1126\/science.abn3107\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1126%2Fscience.abn3107\" aria-label=\"Article reference 54\" data-doi=\"10.1126\/science.abn3107\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXovFeht7s%3D\" aria-label=\"CAS reference 54\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=37104600\" aria-label=\"PubMed reference 54\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10193443\" aria-label=\"PubMed Central reference 54\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 54\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Integrating%20gene%20annotation%20with%20orthology%20inference%20at%20scale&amp;journal=Science&amp;doi=10.1126%2Fscience.abn3107&amp;volume=380&amp;publication_year=2023&amp;author=Kirilenko%2CBM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR55\">Saberi, A., Jamal, A., Beets, I., Schoofs, L. &amp; Newmark, P. A. GPCRs direct germline development and somatic gonad function in planarians. PLOS Biol. 14, e1002457 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1371\/journal.pbio.1002457\" data-track-item_id=\"10.1371\/journal.pbio.1002457\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1371%2Fjournal.pbio.1002457\" aria-label=\"Article reference 55\" data-doi=\"10.1371\/journal.pbio.1002457\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27163480\" aria-label=\"PubMed reference 55\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4862687\" aria-label=\"PubMed Central reference 55\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 55\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GPCRs%20direct%20germline%20development%20and%20somatic%20gonad%20function%20in%20planarians&amp;journal=PLOS%20Biol.&amp;doi=10.1371%2Fjournal.pbio.1002457&amp;volume=14&amp;publication_year=2016&amp;author=Saberi%2CA&amp;author=Jamal%2CA&amp;author=Beets%2CI&amp;author=Schoofs%2CL&amp;author=Newmark%2CPA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR56\">Issigonis, M. &amp; Newmark, P. A. From worm to germ: germ cell development and regeneration in planarians. In Current Topics in Developmental Biology (eds Lehmann, R.) Vol. 135, 127\u2013153 (Elsevier, 2019).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR57\">Brand, J. N. et al. RNA-Seq of three free-living flatworm species suggests rapid evolution of reproduction-related genes. BMC Genom. 21, 462 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12864-020-06862-x\" data-track-item_id=\"10.1186\/s12864-020-06862-x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12864-020-06862-x\" aria-label=\"Article reference 57\" data-doi=\"10.1186\/s12864-020-06862-x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhtlKgtb3K\" aria-label=\"CAS reference 57\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 57\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=RNA-Seq%20of%20three%20free-living%20flatworm%20species%20suggests%20rapid%20evolution%20of%20reproduction-related%20genes&amp;journal=BMC%20Genom.&amp;doi=10.1186%2Fs12864-020-06862-x&amp;volume=21&amp;publication_year=2020&amp;author=Brand%2CJN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR58\">Wilburn, D. B. &amp; Swanson, W. J. From molecules to mating: rapid evolution and biochemical studies of reproductive proteins. J. Proteom. 135, 12\u201325 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.jprot.2015.06.007\" data-track-item_id=\"10.1016\/j.jprot.2015.06.007\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.jprot.2015.06.007\" aria-label=\"Article reference 58\" data-doi=\"10.1016\/j.jprot.2015.06.007\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXhtFKis7bJ\" aria-label=\"CAS reference 58\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 58\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=From%20molecules%20to%20mating%3A%20rapid%20evolution%20and%20biochemical%20studies%20of%20reproductive%20proteins&amp;journal=J.%20Proteom.&amp;doi=10.1016%2Fj.jprot.2015.06.007&amp;volume=135&amp;pages=12-25&amp;publication_year=2016&amp;author=Wilburn%2CDB&amp;author=Swanson%2CWJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR59\">Hershberg, R. &amp; Petrov, D. A. Selection on codon bias. Annu. Rev. Genet. 42, 287\u2013299 (2008).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1146\/annurev.genet.42.110807.091442\" data-track-item_id=\"10.1146\/annurev.genet.42.110807.091442\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1146%2Fannurev.genet.42.110807.091442\" aria-label=\"Article reference 59\" data-doi=\"10.1146\/annurev.genet.42.110807.091442\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD1cXhsFemtbrP\" aria-label=\"CAS reference 59\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=18983258\" aria-label=\"PubMed reference 59\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 59\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Selection%20on%20codon%20bias&amp;journal=Annu.%20Rev.%20Genet.&amp;doi=10.1146%2Fannurev.genet.42.110807.091442&amp;volume=42&amp;pages=287-299&amp;publication_year=2008&amp;author=Hershberg%2CR&amp;author=Petrov%2CDA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR60\">Leung, W. et al. Drosophila muller F elements maintain a distinct set of genomic properties over 40 million years of evolution. G3. 5, 719\u2013740 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/g3.114.015966\" data-track-item_id=\"10.1534\/g3.114.015966\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fg3.114.015966\" aria-label=\"Article reference 60\" data-doi=\"10.1534\/g3.114.015966\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25740935\" aria-label=\"PubMed reference 60\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4426361\" aria-label=\"PubMed Central reference 60\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 60\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Drosophila%20muller%20F%20elements%20maintain%20a%20distinct%20set%20of%20genomic%20properties%20over%2040%20million%20years%20of%20evolution&amp;journal=G3&amp;doi=10.1534%2Fg3.114.015966&amp;volume=5&amp;pages=719-740&amp;publication_year=2015&amp;author=Leung%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR61\">D\u2019Souza, T. G. &amp; Michiels, N. K. The costs and benefits of occasional sex: theoretical predictions and a case study. J. Hered. 101, S34\u2013S41 (2010).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/jhered\/esq005\" data-track-item_id=\"10.1093\/jhered\/esq005\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fjhered%2Fesq005\" aria-label=\"Article reference 61\" data-doi=\"10.1093\/jhered\/esq005\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=20212007\" aria-label=\"PubMed reference 61\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 61\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20costs%20and%20benefits%20of%20occasional%20sex%3A%20theoretical%20predictions%20and%20a%20case%20study&amp;journal=J.%20Hered.&amp;doi=10.1093%2Fjhered%2Fesq005&amp;volume=101&amp;pages=S34-S41&amp;publication_year=2010&amp;author=D%E2%80%99Souza%2CTG&amp;author=Michiels%2CNK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR62\">Sagorny, C. &amp; von D\u00f6hren, J. Occasional sexual reproduction significantly affects the population structure of the widespread, predominantly asexually reproducing marine worm Lineus sanguineus (Nemertea: Pilidiophora). Mar. Biol. 169, 92 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s00227-022-04077-0\" data-track-item_id=\"10.1007\/s00227-022-04077-0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s00227-022-04077-0\" aria-label=\"Article reference 62\" data-doi=\"10.1007\/s00227-022-04077-0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XitVOitrzO\" aria-label=\"CAS reference 62\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 62\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Occasional%20sexual%20reproduction%20significantly%20affects%20the%20population%20structure%20of%20the%20widespread%2C%20predominantly%20asexually%20reproducing%20marine%20worm%20Lineus%20sanguineus%20%28Nemertea%3A%20Pilidiophora%29&amp;journal=Mar.%20Biol.&amp;doi=10.1007%2Fs00227-022-04077-0&amp;volume=169&amp;publication_year=2022&amp;author=Sagorny%2CC&amp;author=D%C3%B6hren%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR63\">Benazzi, M., Bagun\u00e1, J., Ballester, R., Puccinelli, I. &amp; Papa, R. D. Further contribution to the taxonomy of the \u00abDugesia lugubris-polychroa Group\u00bb with description of Dugesia mediterranea n.sp. (tricladida, paludicola). Boll. Zool 42, 81\u201389 (1975).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/11250007509430132\" data-track-item_id=\"10.1080\/11250007509430132\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F11250007509430132\" aria-label=\"Article reference 63\" data-doi=\"10.1080\/11250007509430132\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 63\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Further%20contribution%20to%20the%20taxonomy%20of%20the%20%C2%ABDugesia%20lugubris-polychroa%20Group%C2%BB%20with%20description%20of%20Dugesia%20mediterranea%20n.sp.%20%28tricladida%2C%20paludicola%29&amp;journal=Boll.%20Zool&amp;doi=10.1080%2F11250007509430132&amp;volume=42&amp;pages=81-89&amp;publication_year=1975&amp;author=Benazzi%2CM&amp;author=Bagun%C3%A1%2CJ&amp;author=Ballester%2CR&amp;author=Puccinelli%2CI&amp;author=Papa%2CRD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR64\">Stocchino, G. A. &amp; Manconi, R. Overview of life cycles in model species of the genus Dugesia (Platyhelminthes: Tricladida). Ital. J. Zool. 80, 319\u2013328 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/11250003.2013.822025\" data-track-item_id=\"10.1080\/11250003.2013.822025\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F11250003.2013.822025\" aria-label=\"Article reference 64\" data-doi=\"10.1080\/11250003.2013.822025\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 64\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Overview%20of%20life%20cycles%20in%20model%20species%20of%20the%20genus%20Dugesia%20%28Platyhelminthes%3A%20Tricladida%29&amp;journal=Ital.%20J.%20Zool.&amp;doi=10.1080%2F11250003.2013.822025&amp;volume=80&amp;pages=319-328&amp;publication_year=2013&amp;author=Stocchino%2CGA&amp;author=Manconi%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR65\">Kobayashi, K., Koyanagi, R., Matsumoto, M., Cabrera, J. P. &amp; Hoshi, M. Switching from asexual to sexual reproduction in the planarian dugesia ryukyuensis: bioassay system and basic description of sexualizing process. Zoolog. Sci. 16, 291\u2013298 (1999).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.2108\/zsj.16.291\" data-track-item_id=\"10.2108\/zsj.16.291\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.2108%2Fzsj.16.291\" aria-label=\"Article reference 65\" data-doi=\"10.2108\/zsj.16.291\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 65\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Switching%20from%20asexual%20to%20sexual%20reproduction%20in%20the%20planarian%20dugesia%20ryukyuensis%3A%20bioassay%20system%20and%20basic%20description%20of%20sexualizing%20process&amp;journal=Zoolog.%20Sci.&amp;doi=10.2108%2Fzsj.16.291&amp;volume=16&amp;pages=291-298&amp;publication_year=1999&amp;author=Kobayashi%2CK&amp;author=Koyanagi%2CR&amp;author=Matsumoto%2CM&amp;author=Cabrera%2CJP&amp;author=Hoshi%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR66\">Falconer, D. S. &amp; Mackay, T. Introduction to Quantitative Genetics (Pearson, 2009).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR67\">Mathew, B., L\u00e9on, J. &amp; Sillanp\u00e4\u00e4, M. J. A novel linkage-disequilibrium corrected genomic relationship matrix for SNP-heritability estimation and genomic prediction. Heredity 120, 356\u2013368 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41437-017-0023-4\" data-track-item_id=\"10.1038\/s41437-017-0023-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41437-017-0023-4\" aria-label=\"Article reference 67\" data-doi=\"10.1038\/s41437-017-0023-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXktV2qs7Y%3D\" aria-label=\"CAS reference 67\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29238077\" aria-label=\"PubMed reference 67\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 67\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20novel%20linkage-disequilibrium%20corrected%20genomic%20relationship%20matrix%20for%20SNP-heritability%20estimation%20and%20genomic%20prediction&amp;journal=Heredity&amp;doi=10.1038%2Fs41437-017-0023-4&amp;volume=120&amp;pages=356-368&amp;publication_year=2018&amp;author=Mathew%2CB&amp;author=L%C3%A9on%2CJ&amp;author=Sillanp%C3%A4%C3%A4%2CMJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR68\">Lynch, M., Ye, Z., Urban, L., Maruki, T. &amp; Wei, W. The linkage-disequilibrium and recombinational landscape in Daphnia pulex. Genome Biol. Evol. 14, evac145 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gbe\/evac145\" data-track-item_id=\"10.1093\/gbe\/evac145\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgbe%2Fevac145\" aria-label=\"Article reference 68\" data-doi=\"10.1093\/gbe\/evac145\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36170345\" aria-label=\"PubMed reference 68\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9642108\" aria-label=\"PubMed Central reference 68\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 68\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20linkage-disequilibrium%20and%20recombinational%20landscape%20in%20Daphnia%20pulex&amp;journal=Genome%20Biol.%20Evol.&amp;doi=10.1093%2Fgbe%2Fevac145&amp;volume=14&amp;publication_year=2022&amp;author=Lynch%2CM&amp;author=Ye%2CZ&amp;author=Urban%2CL&amp;author=Maruki%2CT&amp;author=Wei%2CW\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR69\">Wang, Y., Zayas, R. M., Guo, T. &amp; Newmark, P. A. nanos function is essential for development and regeneration of planarian germ cells. Proc. Natl. Acad. Sci. USA. 104, 5901\u20135906 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.0609708104\" data-track-item_id=\"10.1073\/pnas.0609708104\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.0609708104\" aria-label=\"Article reference 69\" data-doi=\"10.1073\/pnas.0609708104\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2007PNAS..104.5901W\" aria-label=\"ADS reference 69\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXkt1Kgt7Y%3D\" aria-label=\"CAS reference 69\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17376870\" aria-label=\"PubMed reference 69\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1851589\" aria-label=\"PubMed Central reference 69\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 69\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=nanos%20function%20is%20essential%20for%20development%20and%20regeneration%20of%20planarian%20germ%20cells&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.0609708104&amp;volume=104&amp;pages=5901-5906&amp;publication_year=2007&amp;author=Wang%2CY&amp;author=Zayas%2CRM&amp;author=Guo%2CT&amp;author=Newmark%2CPA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR70\">Sato, K. et al. Identification and origin of the germline stem cells as revealed by the expression of nanos-related gene in planarians. Dev. Growth Differ. 48, 615\u2013628 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1440-169X.2006.00897.x\" data-track-item_id=\"10.1111\/j.1440-169X.2006.00897.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1440-169X.2006.00897.x\" aria-label=\"Article reference 70\" data-doi=\"10.1111\/j.1440-169X.2006.00897.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXnt1elug%3D%3D\" aria-label=\"CAS reference 70\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17118016\" aria-label=\"PubMed reference 70\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 70\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Identification%20and%20origin%20of%20the%20germline%20stem%20cells%20as%20revealed%20by%20the%20expression%20of%20nanos-related%20gene%20in%20planarians&amp;journal=Dev.%20Growth%20Differ.&amp;doi=10.1111%2Fj.1440-169X.2006.00897.x&amp;volume=48&amp;pages=615-628&amp;publication_year=2006&amp;author=Sato%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR71\">Handberg-Thorsager, M. &amp; Sal\u00f3, E. The planarian nanos-like gene Smednos is expressed in germline and eye precursor cells during development and regeneration. Dev. Genes Evol. 217, 403\u2013411 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s00427-007-0146-3\" data-track-item_id=\"10.1007\/s00427-007-0146-3\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s00427-007-0146-3\" aria-label=\"Article reference 71\" data-doi=\"10.1007\/s00427-007-0146-3\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXks1agtbw%3D\" aria-label=\"CAS reference 71\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17390146\" aria-label=\"PubMed reference 71\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 71\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=The%20planarian%20nanos-like%20gene%20Smednos%20is%20expressed%20in%20germline%20and%20eye%20precursor%20cells%20during%20development%20and%20regeneration&amp;journal=Dev.%20Genes%20Evol.&amp;doi=10.1007%2Fs00427-007-0146-3&amp;volume=217&amp;pages=403-411&amp;publication_year=2007&amp;author=Handberg-Thorsager%2CM&amp;author=Sal%C3%B3%2CE\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR72\">Kershenbaum, S. et al. Variation in phenotype, genotype, and somatic diversity among asexual Schmidtea mediterranea planarians. iScience 28, 113035 (2025).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR73\">Welch, D. B. M. &amp; Meselson, M. S. Rates of nucleotide substitution in sexual and anciently asexual rotifers. Proc. Natl. Acad. Sci. USA 98, 6720\u20136724 (2001).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1073\/pnas.111144598\" data-track-item_id=\"10.1073\/pnas.111144598\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1073%2Fpnas.111144598\" aria-label=\"Article reference 73\" data-doi=\"10.1073\/pnas.111144598\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2001PNAS...98.6720W\" aria-label=\"ADS reference 73\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD3MXksVOkurg%3D\" aria-label=\"CAS reference 73\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 73\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Rates%20of%20nucleotide%20substitution%20in%20sexual%20and%20anciently%20asexual%20rotifers&amp;journal=Proc.%20Natl.%20Acad.%20Sci.%20USA&amp;doi=10.1073%2Fpnas.111144598&amp;volume=98&amp;pages=6720-6724&amp;publication_year=2001&amp;author=Welch%2CDBM&amp;author=Meselson%2CMS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR74\">Ceplitis, A. Coalescence times and the Meselson effect in asexual eukaryotes. Genet. Res. 82, 183\u2013190 (2003).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1017\/S0016672303006487\" data-track-item_id=\"10.1017\/S0016672303006487\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1017%2FS0016672303006487\" aria-label=\"Article reference 74\" data-doi=\"10.1017\/S0016672303006487\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=15134197\" aria-label=\"PubMed reference 74\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 74\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Coalescence%20times%20and%20the%20Meselson%20effect%20in%20asexual%20eukaryotes&amp;journal=Genet.%20Res.&amp;doi=10.1017%2FS0016672303006487&amp;volume=82&amp;pages=183-190&amp;publication_year=2003&amp;author=Ceplitis%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR75\">Flot, J.-F. et al. Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga. Nature 500, 453\u2013457 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nature12326\" data-track-item_id=\"10.1038\/nature12326\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnature12326\" aria-label=\"Article reference 75\" data-doi=\"10.1038\/nature12326\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2013Natur.500..453F\" aria-label=\"ADS reference 75\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXhtFCku7zL\" aria-label=\"CAS reference 75\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23873043\" aria-label=\"PubMed reference 75\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 75\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genomic%20evidence%20for%20ameiotic%20evolution%20in%20the%20bdelloid%20rotifer%20Adineta%20vaga&amp;journal=Nature&amp;doi=10.1038%2Fnature12326&amp;volume=500&amp;pages=453-457&amp;publication_year=2013&amp;author=Flot%2CJ-F\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR76\">Fradin, H. et al. Genome Architecture and Evolution of a Unichromosomal Asexual Nematode. Curr. Biol. 27, 2928\u20132939.e6 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cub.2017.08.038\" data-track-item_id=\"10.1016\/j.cub.2017.08.038\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cub.2017.08.038\" aria-label=\"Article reference 76\" data-doi=\"10.1016\/j.cub.2017.08.038\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2sXhsFKjtbzM\" aria-label=\"CAS reference 76\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=28943090\" aria-label=\"PubMed reference 76\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5659720\" aria-label=\"PubMed Central reference 76\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 76\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genome%20Architecture%20and%20Evolution%20of%20a%20Unichromosomal%20Asexual%20Nematode&amp;journal=Curr.%20Biol.&amp;doi=10.1016%2Fj.cub.2017.08.038&amp;volume=27&amp;pages=2928-2939.e6&amp;publication_year=2017&amp;author=Fradin%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR77\">Sch\u00f6n, I. Lost Sex: The Evolutionary Biology of Parthenogenesis (Springer, 2009).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR78\">King, M. Species Evolution: The Role of Chromosome Change (Cambridge University Press, 1995).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR79\">Kirkpatrick, M. &amp; Barton, N. Chromosome inversions, local adaptation and speciation. Genetics 173, 419\u2013434 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/genetics.105.047985\" data-track-item_id=\"10.1534\/genetics.105.047985\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fgenetics.105.047985\" aria-label=\"Article reference 79\" data-doi=\"10.1534\/genetics.105.047985\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28XlvF2it7s%3D\" aria-label=\"CAS reference 79\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16204214\" aria-label=\"PubMed reference 79\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 79\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Chromosome%20inversions%2C%20local%20adaptation%20and%20speciation&amp;journal=Genetics&amp;doi=10.1534%2Fgenetics.105.047985&amp;volume=173&amp;pages=419-434&amp;publication_year=2006&amp;author=Kirkpatrick%2CM&amp;author=Barton%2CN\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR80\">Dols-Serrate, D., Leria, L., Aguilar, J. P., Stocchino, G. A. &amp; Riutort, M. Dugesia hepta and Dugesia benazzii (Platyhelminthes: Tricladida): two sympatric species with occasional sex? Org. Divers. Evol. 20, 369\u2013386 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/s13127-020-00438-z\" data-track-item_id=\"10.1007\/s13127-020-00438-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/s13127-020-00438-z\" aria-label=\"Article reference 80\" data-doi=\"10.1007\/s13127-020-00438-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 80\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Dugesia%20hepta%20and%20Dugesia%20benazzii%20%28Platyhelminthes%3A%20Tricladida%29%3A%20two%20sympatric%20species%20with%20occasional%20sex%3F&amp;journal=Org.%20Divers.%20Evol.&amp;doi=10.1007%2Fs13127-020-00438-z&amp;volume=20&amp;pages=369-386&amp;publication_year=2020&amp;author=Dols-Serrate%2CD&amp;author=Leria%2CL&amp;author=Aguilar%2CJP&amp;author=Stocchino%2CGA&amp;author=Riutort%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR81\">Leria, L. et al. Cryptic species delineation in freshwater planarians of the genus Dugesia (Platyhelminthes, Tricladida): extreme intraindividual genetic diversity, morphological stasis, and karyological variability. Mol. Phylogenet. Evol. 143, 106496 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.ympev.2019.05.010\" data-track-item_id=\"10.1016\/j.ympev.2019.05.010\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.ympev.2019.05.010\" aria-label=\"Article reference 81\" data-doi=\"10.1016\/j.ympev.2019.05.010\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31151789\" aria-label=\"PubMed reference 81\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 81\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Cryptic%20species%20delineation%20in%20freshwater%20planarians%20of%20the%20genus%20Dugesia%20%28Platyhelminthes%2C%20Tricladida%29%3A%20extreme%20intraindividual%20genetic%20diversity%2C%20morphological%20stasis%2C%20and%20karyological%20variability&amp;journal=Mol.%20Phylogenet.%20Evol.&amp;doi=10.1016%2Fj.ympev.2019.05.010&amp;volume=143&amp;publication_year=2020&amp;author=Leria%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR82\">Tamura, S., Oki, I. &amp; Kawakatsu, M. A review of chromosomal variation in Dugesia japonica and D. ryukyuensis in the Far East. Hydrobiologia 305, 79\u201384 (1995).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1007\/BF00036366\" data-track-item_id=\"10.1007\/BF00036366\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1007\/BF00036366\" aria-label=\"Article reference 82\" data-doi=\"10.1007\/BF00036366\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=1995HyBio.305...79T\" aria-label=\"ADS reference 82\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 82\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20review%20of%20chromosomal%20variation%20in%20Dugesia%20japonica%20and%20D.%20ryukyuensis%20in%20the%20Far%20East&amp;journal=Hydrobiologia&amp;doi=10.1007%2FBF00036366&amp;volume=305&amp;pages=79-84&amp;publication_year=1995&amp;author=Tamura%2CS&amp;author=Oki%2CI&amp;author=Kawakatsu%2CM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR83\">Guo, L. et al. An adaptable chromosome preparation methodology for use in invertebrate research organisms. BMC Biol. 16, 25 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12915-018-0497-4\" data-track-item_id=\"10.1186\/s12915-018-0497-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12915-018-0497-4\" aria-label=\"Article reference 83\" data-doi=\"10.1186\/s12915-018-0497-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=29482548\" aria-label=\"PubMed reference 83\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5828064\" aria-label=\"PubMed Central reference 83\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 83\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=An%20adaptable%20chromosome%20preparation%20methodology%20for%20use%20in%20invertebrate%20research%20organisms&amp;journal=BMC%20Biol.&amp;doi=10.1186%2Fs12915-018-0497-4&amp;volume=16&amp;publication_year=2018&amp;author=Guo%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR84\">Sch\u00e4rer, L. et al. A phylogenetically informed search for an alternative Macrostomum model species, with notes on taxonomy, mating behavior, karyology, and genome size. J. Zool. Syst. Evol. Res. 58, 41\u201365 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/jzs.12344\" data-track-item_id=\"10.1111\/jzs.12344\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fjzs.12344\" aria-label=\"Article reference 84\" data-doi=\"10.1111\/jzs.12344\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 84\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20phylogenetically%20informed%20search%20for%20an%20alternative%20Macrostomum%20model%20species%2C%20with%20notes%20on%20taxonomy%2C%20mating%20behavior%2C%20karyology%2C%20and%20genome%20size&amp;journal=J.%20Zool.%20Syst.%20Evol.%20Res.&amp;doi=10.1111%2Fjzs.12344&amp;volume=58&amp;pages=41-65&amp;publication_year=2020&amp;author=Sch%C3%A4rer%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR85\">Zadesenets, K. S., Jetybayev, I. Y., Sch\u00e4rer, L. &amp; Rubtsov, N. B. Genome and karyotype reorganization after whole genome duplication in free-living flatworms of the genus Macrostomum. Int. J. Mol. Sci. 21, 680 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.3390\/ijms21020680\" data-track-item_id=\"10.3390\/ijms21020680\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.3390%2Fijms21020680\" aria-label=\"Article reference 85\" data-doi=\"10.3390\/ijms21020680\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhslCgsLzL\" aria-label=\"CAS reference 85\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31968653\" aria-label=\"PubMed reference 85\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7013459\" aria-label=\"PubMed Central reference 85\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 85\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genome%20and%20karyotype%20reorganization%20after%20whole%20genome%20duplication%20in%20free-living%20flatworms%20of%20the%20genus%20Macrostomum&amp;journal=Int.%20J.%20Mol.%20Sci.&amp;doi=10.3390%2Fijms21020680&amp;volume=21&amp;publication_year=2020&amp;author=Zadesenets%2CKS&amp;author=Jetybayev%2CIY&amp;author=Sch%C3%A4rer%2CL&amp;author=Rubtsov%2CNB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR86\">Zadesenets, K. S., Ershov, N. I., Bondar, N. P. &amp; Rubtsov, N. B. Unraveling the Unusual Subgenomic Organization in the Neopolyploid Free-Living Flatworm Macrostomum lignano. Mol. Biol. Evol. 40, msad250 (2023).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR87\">Charlesworth, D. Evolution: a can of (flat)worms. Curr. Biol. 32, R918\u2013R921 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cub.2022.07.043\" data-track-item_id=\"10.1016\/j.cub.2022.07.043\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cub.2022.07.043\" aria-label=\"Article reference 87\" data-doi=\"10.1016\/j.cub.2022.07.043\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XitlKrtrbP\" aria-label=\"CAS reference 87\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36099896\" aria-label=\"PubMed reference 87\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 87\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Evolution%3A%20a%20can%20of%20%28flat%29worms&amp;journal=Curr.%20Biol.&amp;doi=10.1016%2Fj.cub.2022.07.043&amp;volume=32&amp;pages=R918-R921&amp;publication_year=2022&amp;author=Charlesworth%2CD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR88\">Golczyk, H., Massouh, A. &amp; Greiner, S. Translocations of chromosome end-segments and facultative heterochromatin promote meiotic ring formation in evening primroses. Plant Cell 26, 1280\u20131293 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1105\/tpc.114.122655\" data-track-item_id=\"10.1105\/tpc.114.122655\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1105%2Ftpc.114.122655\" aria-label=\"Article reference 88\" data-doi=\"10.1105\/tpc.114.122655\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXotV2ktbo%3D\" aria-label=\"CAS reference 88\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=24681616\" aria-label=\"PubMed reference 88\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4001384\" aria-label=\"PubMed Central reference 88\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 88\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Translocations%20of%20chromosome%20end-segments%20and%20facultative%20heterochromatin%20promote%20meiotic%20ring%20formation%20in%20evening%20primroses&amp;journal=Plant%20Cell&amp;doi=10.1105%2Ftpc.114.122655&amp;volume=26&amp;pages=1280-1293&amp;publication_year=2014&amp;author=Golczyk%2CH&amp;author=Massouh%2CA&amp;author=Greiner%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR89\">Tilquin, A. &amp; Kokko, H. What does the geography of parthenogenesis teach us about sex? Philos. Trans. R. Soc. B Biol. Sci. 371, 20150538 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1098\/rstb.2015.0538\" data-track-item_id=\"10.1098\/rstb.2015.0538\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1098%2Frstb.2015.0538\" aria-label=\"Article reference 89\" data-doi=\"10.1098\/rstb.2015.0538\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 89\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=What%20does%20the%20geography%20of%20parthenogenesis%20teach%20us%20about%20sex%3F&amp;journal=Philos.%20Trans.%20R.%20Soc.%20B%20Biol.%20Sci.&amp;doi=10.1098%2Frstb.2015.0538&amp;volume=371&amp;publication_year=2016&amp;author=Tilquin%2CA&amp;author=Kokko%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR90\">Sluys, R. A Monograph of the Marine Triclads (Routledge, 2017).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR91\">Wiberg, R. A. W., Brand, J. N. &amp; Sch\u00e4rer, L. Faster rates of molecular sequence evolution in reproduction-related genes and in species with hypodermic sperm morphologies. Mol. Biol. Evol. <a href=\"https:\/\/doi.org\/10.1093\/molbev\/msab276\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1093\/molbev\/msab276\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1093\/molbev\/msab276<\/a> (2021).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR92\">Wiberg, R. A. W., Viktorin, G. &amp; Sch\u00e4rer, L. Mating strategy predicts gene presence\/absence patterns in a genus of simultaneously hermaphroditic flatworms. Evol. 76, 3054\u20133066 (2022).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR93\">Kondrashov, A. S. Mutation load under vegetative reproduction and cytoplasmic inheritance. Genetics 137, 311\u2013318 (1994).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/genetics\/137.1.311\" data-track-item_id=\"10.1093\/genetics\/137.1.311\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgenetics%2F137.1.311\" aria-label=\"Article reference 93\" data-doi=\"10.1093\/genetics\/137.1.311\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:STN:280:DyaK2czjtlOqsA%3D%3D\" aria-label=\"CAS reference 93\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=8056318\" aria-label=\"PubMed reference 93\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1205947\" aria-label=\"PubMed Central reference 93\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 93\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Mutation%20load%20under%20vegetative%20reproduction%20and%20cytoplasmic%20inheritance&amp;journal=Genetics&amp;doi=10.1093%2Fgenetics%2F137.1.311&amp;volume=137&amp;pages=311-318&amp;publication_year=1994&amp;author=Kondrashov%2CAS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR94\">Kershenbaum, S., Jara-Espejo, M., Griffin, A. S. &amp; Aboobaker, A. Gene conversion limits the cost of asexuality in somatically immortal worms. Preprint at <a href=\"https:\/\/doi.org\/10.1101\/2023.03.20.533553\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/2023.03.20.533553\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/2023.03.20.533553<\/a> (2024).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR95\">Yu, L. et al. Somatic genetic drift and multilevel selection in a clonal seagrass. Nat. Ecol. Evol. 4, 952\u2013962 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41559-020-1196-4\" data-track-item_id=\"10.1038\/s41559-020-1196-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41559-020-1196-4\" aria-label=\"Article reference 95\" data-doi=\"10.1038\/s41559-020-1196-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32393866\" aria-label=\"PubMed reference 95\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 95\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Somatic%20genetic%20drift%20and%20multilevel%20selection%20in%20a%20clonal%20seagrass&amp;journal=Nat.%20Ecol.%20Evol.&amp;doi=10.1038%2Fs41559-020-1196-4&amp;volume=4&amp;pages=952-962&amp;publication_year=2020&amp;author=Yu%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR96\">Yu, L. et al. A somatic genetic clock for clonal species. Nat. Ecol. Evol. 8, 1327\u20131336 (2024).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41559-024-02439-z\" data-track-item_id=\"10.1038\/s41559-024-02439-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41559-024-02439-z\" aria-label=\"Article reference 96\" data-doi=\"10.1038\/s41559-024-02439-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=38858515\" aria-label=\"PubMed reference 96\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11239492\" aria-label=\"PubMed Central reference 96\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 96\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20somatic%20genetic%20clock%20for%20clonal%20species&amp;journal=Nat.%20Ecol.%20Evol.&amp;doi=10.1038%2Fs41559-024-02439-z&amp;volume=8&amp;pages=1327-1336&amp;publication_year=2024&amp;author=Yu%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR97\">Reusch, T. B. H., Baums, I. B. &amp; Werner, B. Evolution via somatic genetic variation in modular species. Trends Ecol. Evol. <a href=\"https:\/\/doi.org\/10.1016\/j.tree.2021.08.011\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1016\/j.tree.2021.08.011\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1016\/j.tree.2021.08.011<\/a> (2021).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR98\">Buss, L. W. The Evolution of Individuality <a href=\"https:\/\/doi.org\/10.1515\/9781400858712\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1515\/9781400858712\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1515\/9781400858712<\/a> (Princeton University Press, 1988).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR99\">Durand, N. C. et al. Juicer provides a one-click system for analyzing loop-resolution Hi-C experiments. Cell Syst. 3, 95\u201398 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1016\/j.cels.2016.07.002\" data-track-item_id=\"10.1016\/j.cels.2016.07.002\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1016%2Fj.cels.2016.07.002\" aria-label=\"Article reference 99\" data-doi=\"10.1016\/j.cels.2016.07.002\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2sXhtFKksbk%3D\" aria-label=\"CAS reference 99\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27467249\" aria-label=\"PubMed reference 99\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5846465\" aria-label=\"PubMed Central reference 99\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 99\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Juicer%20provides%20a%20one-click%20system%20for%20analyzing%20loop-resolution%20Hi-C%20experiments&amp;journal=Cell%20Syst.&amp;doi=10.1016%2Fj.cels.2016.07.002&amp;volume=3&amp;pages=95-98&amp;publication_year=2016&amp;author=Durand%2CNC\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR100\">Wingett S. W. et al. HiCUP: pipeline for mapping and processing Hi-C data [version 1; peer review: 2 approved, 1 approved with reservations]. F1000Research 2015, 4:1310 (2015).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR101\">Kerpedjiev, P. et al. HiGlass: web-based visual exploration and analysis of genome interaction maps. Genome Biol. 19, 125 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-018-1486-1\" data-track-item_id=\"10.1186\/s13059-018-1486-1\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-018-1486-1\" aria-label=\"Article reference 101\" data-doi=\"10.1186\/s13059-018-1486-1\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30143029\" aria-label=\"PubMed reference 101\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6109259\" aria-label=\"PubMed Central reference 101\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 101\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=HiGlass%3A%20web-based%20visual%20exploration%20and%20analysis%20of%20genome%20interaction%20maps&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-018-1486-1&amp;volume=19&amp;publication_year=2018&amp;author=Kerpedjiev%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR102\">Cheng, H., Concepcion, G. T., Feng, X., Zhang, H. &amp; Li, H. Haplotype-resolved de novo assembly using phased assembly graphs with hifiasm. Nat. Methods 18, 170\u2013175 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/s41592-020-01056-5\" data-track-item_id=\"10.1038\/s41592-020-01056-5\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fs41592-020-01056-5\" aria-label=\"Article reference 102\" data-doi=\"10.1038\/s41592-020-01056-5\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3MXis1OntL0%3D\" aria-label=\"CAS reference 102\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33526886\" aria-label=\"PubMed reference 102\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7961889\" aria-label=\"PubMed Central reference 102\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 102\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Haplotype-resolved%20de%20novo%20assembly%20using%20phased%20assembly%20graphs%20with%20hifiasm&amp;journal=Nat.%20Methods&amp;doi=10.1038%2Fs41592-020-01056-5&amp;volume=18&amp;pages=170-175&amp;publication_year=2021&amp;author=Cheng%2CH&amp;author=Concepcion%2CGT&amp;author=Feng%2CX&amp;author=Zhang%2CH&amp;author=Li%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR103\">Ghurye, J., Pop, M., Koren, S., Bickhart, D. &amp; Chin, C.-S. Scaffolding of long read assemblies using long range contact information. BMC Genom. 18, 527 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12864-017-3879-z\" data-track-item_id=\"10.1186\/s12864-017-3879-z\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12864-017-3879-z\" aria-label=\"Article reference 103\" data-doi=\"10.1186\/s12864-017-3879-z\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 103\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Scaffolding%20of%20long%20read%20assemblies%20using%20long%20range%20contact%20information&amp;journal=BMC%20Genom.&amp;doi=10.1186%2Fs12864-017-3879-z&amp;volume=18&amp;publication_year=2017&amp;author=Ghurye%2CJ&amp;author=Pop%2CM&amp;author=Koren%2CS&amp;author=Bickhart%2CD&amp;author=Chin%2CC-S\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR104\">Li, H. New strategies to improve minimap2 alignment accuracy. Bioinformatics 37, 4572\u20134574 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btab705\" data-track-item_id=\"10.1093\/bioinformatics\/btab705\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtab705\" aria-label=\"Article reference 104\" data-doi=\"10.1093\/bioinformatics\/btab705\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XhsFKjs7o%3D\" aria-label=\"CAS reference 104\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34623391\" aria-label=\"PubMed reference 104\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8652018\" aria-label=\"PubMed Central reference 104\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 104\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=New%20strategies%20to%20improve%20minimap2%20alignment%20accuracy&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtab705&amp;volume=37&amp;pages=4572-4574&amp;publication_year=2021&amp;author=Li%2CH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR105\">Goel, M., Sun, H., Jiao, W.-B. &amp; Schneeberger, K. SyRI: finding genomic rearrangements and local sequence differences from whole-genome assemblies. Genome Biol. 20, 277 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-019-1911-0\" data-track-item_id=\"10.1186\/s13059-019-1911-0\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-019-1911-0\" aria-label=\"Article reference 105\" data-doi=\"10.1186\/s13059-019-1911-0\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31842948\" aria-label=\"PubMed reference 105\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6913012\" aria-label=\"PubMed Central reference 105\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 105\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=SyRI%3A%20finding%20genomic%20rearrangements%20and%20local%20sequence%20differences%20from%20whole-genome%20assemblies&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-019-1911-0&amp;volume=20&amp;publication_year=2019&amp;author=Goel%2CM&amp;author=Sun%2CH&amp;author=Jiao%2CW-B&amp;author=Schneeberger%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR106\">Rhie, A., Walenz, B. P., Koren, S. &amp; Phillippy, A. M. Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies. Genome Biol 21, 245 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-020-02134-9\" data-track-item_id=\"10.1186\/s13059-020-02134-9\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-020-02134-9\" aria-label=\"Article reference 106\" data-doi=\"10.1186\/s13059-020-02134-9\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhvVKmu7rF\" aria-label=\"CAS reference 106\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32928274\" aria-label=\"PubMed reference 106\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7488777\" aria-label=\"PubMed Central reference 106\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 106\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Merqury%3A%20reference-free%20quality%2C%20completeness%2C%20and%20phasing%20assessment%20for%20genome%20assemblies&amp;journal=Genome%20Biol&amp;doi=10.1186%2Fs13059-020-02134-9&amp;volume=21&amp;publication_year=2020&amp;author=Rhie%2CA&amp;author=Walenz%2CBP&amp;author=Koren%2CS&amp;author=Phillippy%2CAM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR107\">Ranallo-Benavidez, T. R., Jaron, K. S. &amp; Schatz, M. C. GenomeScope 2.0 and Smudgeplots: reference-free profiling of polyploid genomes. <a href=\"https:\/\/doi.org\/10.1101\/747568\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/747568\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/747568<\/a> (2019).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR108\">Waterhouse, R. M. et al. BUSCO applications from quality assessments to gene prediction and phylogenomics. Mol. Biol. Evol. <a href=\"https:\/\/academic.oup.com\/mbe\/advance-article\/doi\/10.1093\/molbev\/msx319\/4705839\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"https:\/\/academic.oup.com\/mbe\/advance-article\/doi\/10.1093\/molbev\/msx319\/4705839\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/academic.oup.com\/mbe\/advance-article\/doi\/10.1093\/molbev\/msx319\/4705839<\/a> (2017).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR109\">Lakshmanan, V. et al. Genome-wide analysis of polyadenylation events in Schmidtea mediterranea. G3. 6, 3035\u20133048 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/g3.116.031120\" data-track-item_id=\"10.1534\/g3.116.031120\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fg3.116.031120\" aria-label=\"Article reference 109\" data-doi=\"10.1534\/g3.116.031120\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1cXpsVGrsb4%3D\" aria-label=\"CAS reference 109\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27489207\" aria-label=\"PubMed reference 109\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5068929\" aria-label=\"PubMed Central reference 109\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 109\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Genome-wide%20analysis%20of%20polyadenylation%20events%20in%20Schmidtea%20mediterranea&amp;journal=G3&amp;doi=10.1534%2Fg3.116.031120&amp;volume=6&amp;pages=3035-3048&amp;publication_year=2016&amp;author=Lakshmanan%2CV\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR110\">Cantalapiedra, C. P., Hern\u00e1ndez-Plaza, A., Letunic, I., Bork, P. &amp; Huerta-Cepas, J. eggNOG-mapper v2: functional annotation, orthology assignments, and domain prediction at the metagenomic scale. Mol. Biol. Evol. 38, 5825\u20135829 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msab293\" data-track-item_id=\"10.1093\/molbev\/msab293\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsab293\" aria-label=\"Article reference 110\" data-doi=\"10.1093\/molbev\/msab293\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38Xhslyrt78%3D\" aria-label=\"CAS reference 110\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=34597405\" aria-label=\"PubMed reference 110\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8662613\" aria-label=\"PubMed Central reference 110\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 110\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=eggNOG-mapper%20v2%3A%20functional%20annotation%2C%20orthology%20assignments%2C%20and%20domain%20prediction%20at%20the%20metagenomic%20scale&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsab293&amp;volume=38&amp;pages=5825-5829&amp;publication_year=2021&amp;author=Cantalapiedra%2CCP&amp;author=Hern%C3%A1ndez-Plaza%2CA&amp;author=Letunic%2CI&amp;author=Bork%2CP&amp;author=Huerta-Cepas%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR111\">Ou, S. et al. Benchmarking transposable element annotation methods for creation of a streamlined, comprehensive pipeline. Genome Biol. 20, 275 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-019-1905-y\" data-track-item_id=\"10.1186\/s13059-019-1905-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-019-1905-y\" aria-label=\"Article reference 111\" data-doi=\"10.1186\/s13059-019-1905-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC1MXisVSntb3O\" aria-label=\"CAS reference 111\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31843001\" aria-label=\"PubMed reference 111\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6913007\" aria-label=\"PubMed Central reference 111\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 111\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Benchmarking%20transposable%20element%20annotation%20methods%20for%20creation%20of%20a%20streamlined%2C%20comprehensive%20pipeline&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-019-1905-y&amp;volume=20&amp;publication_year=2019&amp;author=Ou%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR112\">Pockrandt, C., Alzamel, M., Iliopoulos, C. S. &amp; Reinert, K. GenMap: ultra-fast computation of genome mappability. Bioinformatics 36, 3687\u20133692 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btaa222\" data-track-item_id=\"10.1093\/bioinformatics\/btaa222\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtaa222\" aria-label=\"Article reference 112\" data-doi=\"10.1093\/bioinformatics\/btaa222\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXisFKgt77N\" aria-label=\"CAS reference 112\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32246826\" aria-label=\"PubMed reference 112\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7320602\" aria-label=\"PubMed Central reference 112\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 112\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GenMap%3A%20ultra-fast%20computation%20of%20genome%20mappability&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtaa222&amp;volume=36&amp;pages=3687-3692&amp;publication_year=2020&amp;author=Pockrandt%2CC&amp;author=Alzamel%2CM&amp;author=Iliopoulos%2CCS&amp;author=Reinert%2CK\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR113\">Chretien, J. H. Characterization of Spermatogenesis in the Planarian S. mediterranea. University of California (2011).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR114\">King, R. S. &amp; Newmark, P. A. Whole-mount in situ hybridization of planarians. in Planarian Regeneration Vol. 1774 (ed. Rink, J. C.) 379\u2013392 (Springer New York, 2018).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR115\">Rouhana, L. et al. RNA interference by feeding in vitro-synthesized double-stranded RNA to planarians: Methodology and dynamics. Dev. Dyn. 242, 718\u2013730 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1002\/dvdy.23950\" data-track-item_id=\"10.1002\/dvdy.23950\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1002%2Fdvdy.23950\" aria-label=\"Article reference 115\" data-doi=\"10.1002\/dvdy.23950\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXotFygsrg%3D\" aria-label=\"CAS reference 115\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23441014\" aria-label=\"PubMed reference 115\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3909682\" aria-label=\"PubMed Central reference 115\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 115\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=RNA%20interference%20by%20feeding%20in%20vitro-synthesized%20double-stranded%20RNA%20to%20planarians%3A%20Methodology%20and%20dynamics&amp;journal=Dev.%20Dyn.&amp;doi=10.1002%2Fdvdy.23950&amp;volume=242&amp;pages=718-730&amp;publication_year=2013&amp;author=Rouhana%2CL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR116\">Liu, S.-Y. &amp; Rink, J. C. Total RNA Isolation from Planarian Tissues Vol. 1774 (Humana Press, 2018).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR117\">Bolger, A. M., Lohse, M. &amp; Usadel, B. Trimmomatic: a flexible trimmer for Illumina sequence data. Bioinformatics 30, 2114\u20132120 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btu170\" data-track-item_id=\"10.1093\/bioinformatics\/btu170\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtu170\" aria-label=\"Article reference 117\" data-doi=\"10.1093\/bioinformatics\/btu170\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXht1Sqt7nP\" aria-label=\"CAS reference 117\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=24695404\" aria-label=\"PubMed reference 117\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4103590\" aria-label=\"PubMed Central reference 117\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 117\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Trimmomatic%3A%20a%20flexible%20trimmer%20for%20Illumina%20sequence%20data&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtu170&amp;volume=30&amp;pages=2114-2120&amp;publication_year=2014&amp;author=Bolger%2CAM&amp;author=Lohse%2CM&amp;author=Usadel%2CB\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR118\">Dobin, A. et al. STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29, 15\u201321 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/bts635\" data-track-item_id=\"10.1093\/bioinformatics\/bts635\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbts635\" aria-label=\"Article reference 118\" data-doi=\"10.1093\/bioinformatics\/bts635\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC38XhvV2gsbnF\" aria-label=\"CAS reference 118\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23104886\" aria-label=\"PubMed reference 118\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 118\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=STAR%3A%20ultrafast%20universal%20RNA-seq%20aligner&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbts635&amp;volume=29&amp;pages=15-21&amp;publication_year=2013&amp;author=Dobin%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR119\">Ritchie, M. E. et al. limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic Acids Res. 43, e47 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nar\/gkv007\" data-track-item_id=\"10.1093\/nar\/gkv007\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnar%2Fgkv007\" aria-label=\"Article reference 119\" data-doi=\"10.1093\/nar\/gkv007\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25605792\" aria-label=\"PubMed reference 119\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4402510\" aria-label=\"PubMed Central reference 119\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 119\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=limma%20powers%20differential%20expression%20analyses%20for%20RNA-sequencing%20and%20microarray%20studies&amp;journal=Nucleic%20Acids%20Res.&amp;doi=10.1093%2Fnar%2Fgkv007&amp;volume=43&amp;publication_year=2015&amp;author=Ritchie%2CME\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR120\">Lovell, J. T. et al. GENESPACE tracks regions of interest and gene copy number variation across multiple genomes. eLife 11, e78526 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.7554\/eLife.78526\" data-track-item_id=\"10.7554\/eLife.78526\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.7554%2FeLife.78526\" aria-label=\"Article reference 120\" data-doi=\"10.7554\/eLife.78526\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3sXisVOltrfO\" aria-label=\"CAS reference 120\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=36083267\" aria-label=\"PubMed reference 120\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9462846\" aria-label=\"PubMed Central reference 120\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 120\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=GENESPACE%20tracks%20regions%20of%20interest%20and%20gene%20copy%20number%20variation%20across%20multiple%20genomes&amp;journal=eLife&amp;doi=10.7554%2FeLife.78526&amp;volume=11&amp;publication_year=2022&amp;author=Lovell%2CJT\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR121\">Emms, D. M. &amp; Kelly, S. OrthoFinder: phylogenetic orthology inference for comparative genomics. Genome Biol. 20, 238 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s13059-019-1832-y\" data-track-item_id=\"10.1186\/s13059-019-1832-y\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s13059-019-1832-y\" aria-label=\"Article reference 121\" data-doi=\"10.1186\/s13059-019-1832-y\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=31727128\" aria-label=\"PubMed reference 121\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6857279\" aria-label=\"PubMed Central reference 121\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 121\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=OrthoFinder%3A%20phylogenetic%20orthology%20inference%20for%20comparative%20genomics&amp;journal=Genome%20Biol.&amp;doi=10.1186%2Fs13059-019-1832-y&amp;volume=20&amp;publication_year=2019&amp;author=Emms%2CDM&amp;author=Kelly%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR122\">Buchfink, B., Xie, C. &amp; Huson, D. H. Fast and sensitive protein alignment using DIAMOND. Nat. Methods 12, 59\u201360 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nmeth.3176\" data-track-item_id=\"10.1038\/nmeth.3176\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnmeth.3176\" aria-label=\"Article reference 122\" data-doi=\"10.1038\/nmeth.3176\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXhvFKlsrzN\" aria-label=\"CAS reference 122\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25402007\" aria-label=\"PubMed reference 122\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 122\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Fast%20and%20sensitive%20protein%20alignment%20using%20DIAMOND&amp;journal=Nat.%20Methods&amp;doi=10.1038%2Fnmeth.3176&amp;volume=12&amp;pages=59-60&amp;publication_year=2015&amp;author=Buchfink%2CB&amp;author=Xie%2CC&amp;author=Huson%2CDH\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR123\">Wang, Y. et al. MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity. Nucleic Acids Res. 40, e49 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nar\/gkr1293\" data-track-item_id=\"10.1093\/nar\/gkr1293\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnar%2Fgkr1293\" aria-label=\"Article reference 123\" data-doi=\"10.1093\/nar\/gkr1293\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"ads reference\" data-track-action=\"ads reference\" href=\"http:\/\/adsabs.harvard.edu\/cgi-bin\/nph-data_query?link_type=ABSTRACT&amp;bibcode=2012moth.book.....W\" aria-label=\"ADS reference 123\" target=\"_blank\">ADS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC38Xls1SmsL0%3D\" aria-label=\"CAS reference 123\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=22217600\" aria-label=\"PubMed reference 123\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3326336\" aria-label=\"PubMed Central reference 123\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 123\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MCScanX%3A%20a%20toolkit%20for%20detection%20and%20evolutionary%20analysis%20of%20gene%20synteny%20and%20collinearity&amp;journal=Nucleic%20Acids%20Res.&amp;doi=10.1093%2Fnar%2Fgkr1293&amp;volume=40&amp;publication_year=2012&amp;author=Wang%2CY\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR124\">Mirchandani, C. D. et al. A fast, reproducible, high-throughput variant calling workflow for population genomics. Mol. Biol. Evol. 41, msad270 (2023).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msad270\" data-track-item_id=\"10.1093\/molbev\/msad270\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsad270\" aria-label=\"Article reference 124\" data-doi=\"10.1093\/molbev\/msad270\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 124\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20fast%2C%20reproducible%2C%20high-throughput%20variant%20calling%20workflow%20for%20population%20genomics&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsad270&amp;volume=41&amp;publication_year=2023&amp;author=Mirchandani%2CCD\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR125\">Borowiec, M. L. AMAS: a fast tool for alignment manipulation and computing of summary statistics. PeerJ. 4, e1660 (2016).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR126\">Minh, B. Q. et al. IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era. Mol. Biol. Evol. 37, 1530\u20131534 (2020).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msaa015\" data-track-item_id=\"10.1093\/molbev\/msaa015\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsaa015\" aria-label=\"Article reference 126\" data-doi=\"10.1093\/molbev\/msaa015\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXis1egsLbL\" aria-label=\"CAS reference 126\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=32011700\" aria-label=\"PubMed reference 126\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7182206\" aria-label=\"PubMed Central reference 126\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 126\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=IQ-TREE%202%3A%20new%20models%20and%20efficient%20methods%20for%20phylogenetic%20inference%20in%20the%20genomic%20era&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsaa015&amp;volume=37&amp;pages=1530-1534&amp;publication_year=2020&amp;author=Minh%2CBQ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR127\">Jia, K.-H. et al. SubPhaser: a robust allopolyploid subgenome phasing method based on subgenome-specific k-mers. New Phytol. 235, 801\u2013809 (2022).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/nph.18173\" data-track-item_id=\"10.1111\/nph.18173\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fnph.18173\" aria-label=\"Article reference 127\" data-doi=\"10.1111\/nph.18173\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB38XhvVeiurjM\" aria-label=\"CAS reference 127\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=35460274\" aria-label=\"PubMed reference 127\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 127\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=SubPhaser%3A%20a%20robust%20allopolyploid%20subgenome%20phasing%20method%20based%20on%20subgenome-specific%20k-mers&amp;journal=New%20Phytol.&amp;doi=10.1111%2Fnph.18173&amp;volume=235&amp;pages=801-809&amp;publication_year=2022&amp;author=Jia%2CK-H\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR128\">Katoh, K. &amp; Standley, D. M. MAFFT multiple sequence alignment software version 7: Improvements in performance and usability. Mol. Biol. Evol. 30, 772\u2013780 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/mst010\" data-track-item_id=\"10.1093\/molbev\/mst010\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmst010\" aria-label=\"Article reference 128\" data-doi=\"10.1093\/molbev\/mst010\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC3sXksFWisLc%3D\" aria-label=\"CAS reference 128\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=23329690\" aria-label=\"PubMed reference 128\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3603318\" aria-label=\"PubMed Central reference 128\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 128\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=MAFFT%20multiple%20sequence%20alignment%20software%20version%207%3A%20Improvements%20in%20performance%20and%20usability&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmst010&amp;volume=30&amp;pages=772-780&amp;publication_year=2013&amp;author=Katoh%2CK&amp;author=Standley%2CDM\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR129\">Suyama, M., Torrents, D. &amp; Bork, P. PAL2NAL: robust conversion of protein sequence alignments into the corresponding codon alignments. Nucleic Acids Res. 34, W609\u2013W612 (2006).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/nar\/gkl315\" data-track-item_id=\"10.1093\/nar\/gkl315\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fnar%2Fgkl315\" aria-label=\"Article reference 129\" data-doi=\"10.1093\/nar\/gkl315\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD28Xps1yhtL8%3D\" aria-label=\"CAS reference 129\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=16845082\" aria-label=\"PubMed reference 129\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1538804\" aria-label=\"PubMed Central reference 129\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 129\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=PAL2NAL%3A%20robust%20conversion%20of%20protein%20sequence%20alignments%20into%20the%20corresponding%20codon%20alignments&amp;journal=Nucleic%20Acids%20Res.&amp;doi=10.1093%2Fnar%2Fgkl315&amp;volume=34&amp;pages=W609-W612&amp;publication_year=2006&amp;author=Suyama%2CM&amp;author=Torrents%2CD&amp;author=Bork%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR130\">Yang, Z. PAML 4: phylogenetic analysis by maximum likelihood. Mol. Biol. Evol. 24, 1586\u20131591 (2007).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/molbev\/msm088\" data-track-item_id=\"10.1093\/molbev\/msm088\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fmolbev%2Fmsm088\" aria-label=\"Article reference 130\" data-doi=\"10.1093\/molbev\/msm088\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2sXpsVGrs7c%3D\" aria-label=\"CAS reference 130\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=17483113\" aria-label=\"PubMed reference 130\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 130\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=PAML%204%3A%20phylogenetic%20analysis%20by%20maximum%20likelihood&amp;journal=Mol.%20Biol.%20Evol.&amp;doi=10.1093%2Fmolbev%2Fmsm088&amp;volume=24&amp;pages=1586-1591&amp;publication_year=2007&amp;author=Yang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR131\">Peden, J. F. Analysis of Codon Usage. University of Nottingham (1999).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR132\">Zhang, Z. et al. Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance. BMC Bioinform. 13, 43 (2012).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/1471-2105-13-43\" data-track-item_id=\"10.1186\/1471-2105-13-43\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/1471-2105-13-43\" aria-label=\"Article reference 132\" data-doi=\"10.1186\/1471-2105-13-43\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 132\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Codon%20Deviation%20Coefficient%3A%20a%20novel%20measure%20for%20estimating%20codon%20usage%20bias%20and%20its%20statistical%20significance&amp;journal=BMC%20Bioinform.&amp;doi=10.1186%2F1471-2105-13-43&amp;volume=13&amp;publication_year=2012&amp;author=Zhang%2CZ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR133\">Vila-Farr\u00e9, M. et al. An integrative taxonomic approach reveals unexplored diversity in Croatian planarians. Front Zool. 23, 13 (2026).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR134\">Kalyaanamoorthy, S. et al. ModelFinder: fast model selection for accurate phylogenetic estimates. Nat. Methods 14, 587\u2013589 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/nmeth.4285\" data-track-item_id=\"10.1038\/nmeth.4285\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fnmeth.4285\" aria-label=\"Article reference 134\" data-doi=\"10.1038\/nmeth.4285\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2sXntFKitbw%3D\" aria-label=\"CAS reference 134\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=28481363\" aria-label=\"PubMed reference 134\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5453245\" aria-label=\"PubMed Central reference 134\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 134\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=ModelFinder%3A%20fast%20model%20selection%20for%20accurate%20phylogenetic%20estimates&amp;journal=Nat.%20Methods&amp;doi=10.1038%2Fnmeth.4285&amp;volume=14&amp;pages=587-589&amp;publication_year=2017&amp;author=Kalyaanamoorthy%2CS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR135\">Guindon, S. &amp; Gascuel, O. A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood. Syst. Biol. 52, 696\u2013704 (2003).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1080\/10635150390235520\" data-track-item_id=\"10.1080\/10635150390235520\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1080%2F10635150390235520\" aria-label=\"Article reference 135\" data-doi=\"10.1080\/10635150390235520\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=14530136\" aria-label=\"PubMed reference 135\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 135\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=A%20simple%2C%20fast%2C%20and%20accurate%20algorithm%20to%20estimate%20large%20phylogenies%20by%20maximum%20likelihood&amp;journal=Syst.%20Biol.&amp;doi=10.1080%2F10635150390235520&amp;volume=52&amp;pages=696-704&amp;publication_year=2003&amp;author=Guindon%2CS&amp;author=Gascuel%2CO\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR136\">Poplin, R. et al. Scaling accurate genetic variant discovery to tens of thousands of samples. Preprint at <a href=\"https:\/\/doi.org\/10.1101\/201178\" data-track=\"click_references\" data-track-action=\"external reference\" data-track-value=\"external reference\" data-track-label=\"10.1101\/201178\" rel=\"nofollow noopener\" target=\"_blank\">https:\/\/doi.org\/10.1101\/201178<\/a> (2018).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR137\">Auwera, G. V. der &amp; O\u2019Connor, B. D. Genomics in the Cloud: Using Docker, GATK, and WDL in Terra (O\u2019Reilly, 2020).<\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR138\">Nelson, C. W., Moncla, L. H. &amp; Hughes, A. L. SNPGenie: estimating evolutionary parameters to detect natural selection using pooled next-generation sequencing data. Bioinformatics 31, 3709\u20133711 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btv449\" data-track-item_id=\"10.1093\/bioinformatics\/btv449\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtv449\" aria-label=\"Article reference 138\" data-doi=\"10.1093\/bioinformatics\/btv449\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC28Xht1CitL%2FI\" aria-label=\"CAS reference 138\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=26227143\" aria-label=\"PubMed reference 138\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4757956\" aria-label=\"PubMed Central reference 138\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 138\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=SNPGenie%3A%20estimating%20evolutionary%20parameters%20to%20detect%20natural%20selection%20using%20pooled%20next-generation%20sequencing%20data&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtv449&amp;volume=31&amp;pages=3709-3711&amp;publication_year=2015&amp;author=Nelson%2CCW&amp;author=Moncla%2CLH&amp;author=Hughes%2CAL\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR139\">Korneliussen, T. S., Albrechtsen, A. &amp; Nielsen, R. ANGSD: analysis of next generation sequencing data. BMC Bioinform. 15, 356 (2014).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"noopener nofollow\" data-track-label=\"10.1186\/s12859-014-0356-4\" data-track-item_id=\"10.1186\/s12859-014-0356-4\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/link.springer.com\/doi\/10.1186\/s12859-014-0356-4\" aria-label=\"Article reference 139\" data-doi=\"10.1186\/s12859-014-0356-4\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 139\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=ANGSD%3A%20analysis%20of%20next%20generation%20sequencing%20data&amp;journal=BMC%20Bioinform.&amp;doi=10.1186%2Fs12859-014-0356-4&amp;volume=15&amp;publication_year=2014&amp;author=Korneliussen%2CTS&amp;author=Albrechtsen%2CA&amp;author=Nielsen%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR140\">Meisner, J. &amp; Albrechtsen, A. Inferring population structure and admixture proportions in low-depth NGS data. Genetics 210, 719\u2013731 (2018).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/genetics.118.301336\" data-track-item_id=\"10.1534\/genetics.118.301336\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fgenetics.118.301336\" aria-label=\"Article reference 140\" data-doi=\"10.1534\/genetics.118.301336\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30131346\" aria-label=\"PubMed reference 140\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6216594\" aria-label=\"PubMed Central reference 140\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 140\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Inferring%20population%20structure%20and%20admixture%20proportions%20in%20low-depth%20NGS%20data&amp;journal=Genetics&amp;doi=10.1534%2Fgenetics.118.301336&amp;volume=210&amp;pages=719-731&amp;publication_year=2018&amp;author=Meisner%2CJ&amp;author=Albrechtsen%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR141\">Skotte, L., Korneliussen, T. S. &amp; Albrechtsen, A. Estimating individual admixture proportions from next generation sequencing data. Genetics 195, 693\u2013702 (2013).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1534\/genetics.113.154138\" data-track-item_id=\"10.1534\/genetics.113.154138\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1534%2Fgenetics.113.154138\" aria-label=\"Article reference 141\" data-doi=\"10.1534\/genetics.113.154138\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2cXhtlGjtLs%3D\" aria-label=\"CAS reference 141\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=24026093\" aria-label=\"PubMed reference 141\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3813857\" aria-label=\"PubMed Central reference 141\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 141\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Estimating%20individual%20admixture%20proportions%20from%20next%20generation%20sequencing%20data&amp;journal=Genetics&amp;doi=10.1534%2Fgenetics.113.154138&amp;volume=195&amp;pages=693-702&amp;publication_year=2013&amp;author=Skotte%2CL&amp;author=Korneliussen%2CTS&amp;author=Albrechtsen%2CA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR142\">Evanno, G., Regnaut, S. &amp; Goudet, J. Detecting the number of clusters of individuals using the software structure: a simulation study. Mol. Ecol. 14, 2611\u20132620 (2005).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/j.1365-294X.2005.02553.x\" data-track-item_id=\"10.1111\/j.1365-294X.2005.02553.x\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2Fj.1365-294X.2005.02553.x\" aria-label=\"Article reference 142\" data-doi=\"10.1111\/j.1365-294X.2005.02553.x\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BD2MXmvF2qtrg%3D\" aria-label=\"CAS reference 142\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=15969739\" aria-label=\"PubMed reference 142\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 142\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Detecting%20the%20number%20of%20clusters%20of%20individuals%20using%20the%20software%20structure%3A%20a%20simulation%20study&amp;journal=Mol.%20Ecol.&amp;doi=10.1111%2Fj.1365-294X.2005.02553.x&amp;volume=14&amp;pages=2611-2620&amp;publication_year=2005&amp;author=Evanno%2CG&amp;author=Regnaut%2CS&amp;author=Goudet%2CJ\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR143\">Kopelman, N. M., Mayzel, J., Jakobsson, M., Rosenberg, N. A. &amp; Mayrose, I. Clumpak: a program for identifying clustering modes and packaging population structure inferences across K. Mol. Ecol. Resour. 15, 1179\u20131191 (2015).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1111\/1755-0998.12387\" data-track-item_id=\"10.1111\/1755-0998.12387\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1111%2F1755-0998.12387\" aria-label=\"Article reference 143\" data-doi=\"10.1111\/1755-0998.12387\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC2MXhtlSmtLzK\" aria-label=\"CAS reference 143\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=25684545\" aria-label=\"PubMed reference 143\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4534335\" aria-label=\"PubMed Central reference 143\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 143\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Clumpak%3A%20a%20program%20for%20identifying%20clustering%20modes%20and%20packaging%20population%20structure%20inferences%20across%20K&amp;journal=Mol.%20Ecol.%20Resour.&amp;doi=10.1111%2F1755-0998.12387&amp;volume=15&amp;pages=1179-1191&amp;publication_year=2015&amp;author=Kopelman%2CNM&amp;author=Mayzel%2CJ&amp;author=Jakobsson%2CM&amp;author=Rosenberg%2CNA&amp;author=Mayrose%2CI\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR144\">Vieira, F. G., Albrechtsen, A. &amp; Nielsen, R. Estimating IBD tracts from low coverage NGS data. Bioinformatics 32, 2096\u20132102 (2016).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btw212\" data-track-item_id=\"10.1093\/bioinformatics\/btw212\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtw212\" aria-label=\"Article reference 144\" data-doi=\"10.1093\/bioinformatics\/btw212\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC28XhvVekt7fM\" aria-label=\"CAS reference 144\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=27153648\" aria-label=\"PubMed reference 144\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 144\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Estimating%20IBD%20tracts%20from%20low%20coverage%20NGS%20data&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtw212&amp;volume=32&amp;pages=2096-2102&amp;publication_year=2016&amp;author=Vieira%2CFG&amp;author=Albrechtsen%2CA&amp;author=Nielsen%2CR\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR145\">Fox, E. A., Wright, A. E., Fumagalli, M. &amp; Vieira, F. G. ngsLD: evaluating linkage disequilibrium using genotype likelihoods. Bioinformatics 35, 3855\u20133856 (2019).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/bioinformatics\/btz200\" data-track-item_id=\"10.1093\/bioinformatics\/btz200\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fbioinformatics%2Fbtz200\" aria-label=\"Article reference 145\" data-doi=\"10.1093\/bioinformatics\/btz200\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BB3cXhtVCjtL7M\" aria-label=\"CAS reference 145\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=30903149\" aria-label=\"PubMed reference 145\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 145\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=ngsLD%3A%20evaluating%20linkage%20disequilibrium%20using%20genotype%20likelihoods&amp;journal=Bioinformatics&amp;doi=10.1093%2Fbioinformatics%2Fbtz200&amp;volume=35&amp;pages=3855-3856&amp;publication_year=2019&amp;author=Fox%2CEA&amp;author=Wright%2CAE&amp;author=Fumagalli%2CM&amp;author=Vieira%2CFG\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR146\">Danecek, P. et al. Twelve years of SAMtools and BCFtools. GigaScience 10, giab008 (2021).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1093\/gigascience\/giab008\" data-track-item_id=\"10.1093\/gigascience\/giab008\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1093%2Fgigascience%2Fgiab008\" aria-label=\"Article reference 146\" data-doi=\"10.1093\/gigascience\/giab008\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=33590861\" aria-label=\"PubMed reference 146\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed central reference\" data-track-action=\"pubmed central reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7931819\" aria-label=\"PubMed Central reference 146\" target=\"_blank\">PubMed Central<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 146\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Twelve%20years%20of%20SAMtools%20and%20BCFtools&amp;journal=GigaScience&amp;doi=10.1093%2Fgigascience%2Fgiab008&amp;volume=10&amp;publication_year=2021&amp;author=Danecek%2CP\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR147\">Terhorst, J., Kamm, J. A. &amp; Song, Y. S. Robust and scalable inference of population history from hundreds of unphased whole genomes. Nat. Genet. 49, 303\u2013309 (2017).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"10.1038\/ng.3748\" data-track-item_id=\"10.1038\/ng.3748\" data-track-value=\"article reference\" data-track-action=\"article reference\" href=\"https:\/\/doi.org\/10.1038%2Fng.3748\" aria-label=\"Article reference 147\" data-doi=\"10.1038\/ng.3748\" target=\"_blank\">Article<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"cas reference\" data-track-action=\"cas reference\" href=\"https:\/\/www.nature.com\/articles\/cas-redirect\/1:CAS:528:DC%2BC28XitFCgu7%2FE\" aria-label=\"CAS reference 147\" target=\"_blank\">CAS<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" rel=\"nofollow noopener\" data-track-label=\"link\" data-track-item_id=\"link\" data-track-value=\"pubmed reference\" data-track-action=\"pubmed reference\" href=\"http:\/\/www.ncbi.nlm.nih.gov\/entrez\/query.fcgi?cmd=Retrieve&amp;db=PubMed&amp;dopt=Abstract&amp;list_uids=28024154\" aria-label=\"PubMed reference 147\" target=\"_blank\">PubMed<\/a>\u00a0<br \/>\n    <a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 147\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Robust%20and%20scalable%20inference%20of%20population%20history%20from%20hundreds%20of%20unphased%20whole%20genomes&amp;journal=Nat.%20Genet.&amp;doi=10.1038%2Fng.3748&amp;volume=49&amp;pages=303-309&amp;publication_year=2017&amp;author=Terhorst%2CJ&amp;author=Kamm%2CJA&amp;author=Song%2CYS\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n<p class=\"c-article-references__text\" id=\"ref-CR148\">Casu, S., Pala, M. &amp; Vacca, R. A. Distribuzione geografica in Sardegna di planarie d\u2019acqua dolce appartenenti alle specie Dugesia (S.) polychroa e Dugesia (S.) mediterranea (Turbellaria, Tricladida). Boll. Soc. Sarda Sci. Nat. 21, 177\u2013184 (1981).<\/p>\n<p class=\"c-article-references__links u-hide-print\"><a data-track=\"click_references\" data-track-action=\"google scholar reference\" data-track-value=\"google scholar reference\" data-track-label=\"link\" data-track-item_id=\"link\" rel=\"nofollow noopener\" aria-label=\"Google Scholar reference 148\" href=\"http:\/\/scholar.google.com\/scholar_lookup?&amp;title=Distribuzione%20geografica%20in%20Sardegna%20di%20planarie%20d%E2%80%99acqua%20dolce%20appartenenti%20alle%20specie%20Dugesia%20%28S.%29%20polychroa%20e%20Dugesia%20%28S.%29%20mediterranea%20%28Turbellaria%2C%20Tricladida%29&amp;journal=Boll.%20Soc.%20Sarda%20Sci.%20Nat.&amp;volume=21&amp;pages=177-184&amp;publication_year=1981&amp;author=Casu%2CS&amp;author=Pala%2CM&amp;author=Vacca%2CRA\" target=\"_blank\"><br \/>\n                    Google Scholar<\/a>\u00a0\n                <\/p>\n","protected":false},"excerpt":{"rendered":"Otto, S. P. The Evolutionary Enigma of Sex. Am. Nat. 174, S1\u2013S14 (2009). Article\u00a0 PubMed\u00a0 Google Scholar\u00a0 Gibson,&hellip;\n","protected":false},"author":2,"featured_media":520711,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[4841,2026,61,60,45949,2027,10883,82,203908],"class_list":["post-520710","post","type-post","status-publish","format-standard","has-post-thumbnail","category-science","tag-haplotypes","tag-humanities-and-social-sciences","tag-ie","tag-ireland","tag-molecular-evolution","tag-multidisciplinary","tag-population-genetics","tag-science","tag-sexual-selection"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/520710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=520710"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/520710\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/520711"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=520710"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=520710"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=520710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}