analysis<\/a> of 44,367 urinary isolates from clinical labs in Benin, Cameroon, Central African Republic, Madagascar, Morocco, and Senegal, a team of investigators assessed drug-resistance trends in Escherichia coli and Klebsiella pneumoniae\u2014two of the primary causative pathogens of UTIs. Data collection spanned from 2008 through 2023, with a shared observation period from October 2014 to December 2021. Resistance was analyzed for seven antibiotic classes in E coli\u00a0and six in K pneumoniae.<\/p>\nThe researchers note that resistance data on E coli and K pneumoniae\u00a0in Africa \u201cremain scarce or fragmented.\u201d<\/p>\n
\u201cMonitoring resistance trends is essential to understanding AMR evolution and intercountry differences and forecasting resistance trajectories,\u201d the study authors wrote. \u201cSuch insights are critical for informing health policy, guiding empirical treatment, and supporting strategies to contain multidrug-resistant organisms.\u201d<\/p>\n
Stronger measures needed<\/p>\n
Resistance to first-line antibiotics was widespread, with amoxicillin resistance in E coli exceeding 85% across sites and amoxicillin-clavulanic acid resistance exceeding 50% in for both pathogens in all countries except Madagascar and Cameroon. Resistance to broader-spectrum antibiotics was also high, with fluoroquinolone resistance exceeding 40% for both pathogens in all sites and resistance to third- and fourth-generation cephalosporins surpassing 45% in all countries except Morocco.<\/p>\n
While resistance to carbapenems\u2014a last-resort antibiotic class\u2014remained below 18% for both pathogens, a modeling projection estimated that carbapenem and third-generation cephalosporin resistance could exceed 90% in all six countries by 2050.<\/p>\n
The authors say the findings indicate that stronger measures against AMR are urgently needed in Africa.<\/p>\n
\u201cThese estimations underscore the urgent need for strengthened standardized stewardship, enhanced surveillance, improved infection prevention and control, and expanded health care capacity,\u201d they wrote.<\/p>\n","protected":false},"excerpt":{"rendered":"Christian Maro \/ iStock A study of urinary tract infections (UTIs) in six African countries found high and…\n","protected":false},"author":2,"featured_media":10568,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60],"class_list":["post-547753","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-ie","tag-ireland"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/547753","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=547753"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/547753\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/10568"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=547753"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=547753"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=547753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
![\"Urine](\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2026\/07\/iStock-2097863092-2.jpg\")