Australia\u2019s medicine regulator has issued a safety warning over popular weight-loss drugs like Ozempic, saying they could cause a rare vision disorder.<\/p>\n
The Therapeutic Goods Administration warned the GLP-1 RA class of medicines have the potential to cause a rare, but severe, form of eye disorder called non-arteritic anterior ischaemic optic neuropathy (NAION).<\/p>\n
The disorder may result in permanent visual impairment, including blindness. There is currently no treatment for it.<\/p>\n
The TGA urges any patients who experience sudden vision loss, even if only partial, should seek urgent medical attention.<\/p>\n
The regulator revealed a potential link between GLP-1 RAs and NAION was first discovered in July 2024 following a JAMA Ophthalmology study.<\/p>\n
TGA then conducted an independent assessment of the link but found the evidence conflicted the original study\u2019s findings.<\/p>\n
\u201cAs the available evidence was conflicting, we sought expert advice from the Advisory Committee on Medicines (ACM) on whether the evidence supported additional risk mitigation measures,\u201d The TGA\u2019s warning stated.<\/p>\n
\u201cFollowing discussion at its October 2025 meeting, the ACM concluded that the current evidence may support the signal for semaglutide, but not dulaglutide or tirzepatide and recommended a range of risk mitigation strategies.\u201d<\/p>\n
\u201cAfter considering all available evidence, including the ACM advice, we made a final decision on regulatory actions including PI and CMI document updates, and publication of safety communications.\u201d<\/p>\n
MEDICINES ON THE LIST:TrulicityOzempicWegovyMounjaroSaxenda<\/p>\n","protected":false},"excerpt":{"rendered":"Australia\u2019s medicine regulator has issued a safety warning over popular weight-loss drugs like Ozempic, saying they could cause…\n","protected":false},"author":2,"featured_media":565455,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[33],"tags":[103,61,60,371,43,2361],"class_list":["post-565454","post","type-post","status-publish","format-standard","has-post-thumbnail","category-medication","tag-health","tag-ie","tag-ireland","tag-medication","tag-news","tag-public-health"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/565454","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=565454"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/565454\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/565455"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=565454"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=565454"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=565454"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}