{"id":612546,"date":"2026-09-02T19:20:12","date_gmt":"2026-09-02T19:20:12","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/612546\/"},"modified":"2026-09-02T19:20:12","modified_gmt":"2026-09-02T19:20:12","slug":"vitamin-d3-more-effective-than-d2-for-restoring-muscle-heart-health-icmr-study","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/612546\/","title":{"rendered":"Vitamin D3 &#8216;more effective&#8217; than D2 for restoring muscle, heart health: ICMR study"},"content":{"rendered":"<p>Vitamin D occurs in nature in two forms: vitamin D3 and vitamin D2.<\/p>\n<p>While D3 is synthesised through sun\/UV exposure and obtained primarily from animal-based foods such as eggs, fish and organ meats and from supplements, D2 is derived from wild, cultivated or sun-dried mushrooms, UV-B-irradiated yeast, plant-based sources and some dietary supplements.<\/p>\n<p>For food fortification, both D2 and D3 are used. However, D2 is a more preferred fortificant in certain countries due to widespread vegetarianism or among people who follow a strict vegan diet.<\/p>\n<p>\u201cVitamin D plays an important role in modulating skeletal muscle mass, structure, and function, however, the differential impact of D2 and D3 remains inconclusive. In this study, we found that D3 has a greater impact than D2 in improving skeletal muscle size and function during both maintenance and recovery phase,\u201d the study said.<\/p>\n<p>While both forms are used in supplements and food fortification, evidence on whether the two forms have similar effects beyond bone health has remained limited.<\/p>\n<p>To study the differences between the two forms, the researchers used weaning male Sprague-Dawley rats and fed them diets containing vitamin D2, vitamin D3, a combination of both, or a vitamin D-deficient diet.<\/p>\n<p>The researchers assessed body composition, muscle strength, skeletal muscle structure and metabolism, and markers related to cardiac function.<\/p>\n<p>Dr Bharati Kulkarni, Director, ICMR-NIN, said, \u201cThe findings indicate that vitamin D3 may be more effective than vitamin D2 in maintaining and restoring skeletal muscle and cardiac functions.\u201d<\/p>\n<p>She said further studies are needed to establish the effects of the two forms of vitamin D on skeletal and extra-skeletal functions and their implications for supplementation and fortification programmes.<\/p>\n<p>According to the World Health Organisation-Food and Agriculture Organisation (WHO-FAO), micronutrient supplementation is the fastest method to improve the micronutrient status of populations, while fortification can be a cost-effective public health intervention with a sustained impact.<\/p>\n","protected":false},"excerpt":{"rendered":"Vitamin D occurs in nature in two forms: vitamin D3 and vitamin D2. While D3 is synthesised through&hellip;\n","protected":false},"author":2,"featured_media":612547,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[36],"tags":[103,4037,61,60,259543,446,43592,12368],"class_list":["post-612546","post","type-post","status-publish","format-standard","has-post-thumbnail","category-nutrition","tag-health","tag-heart-health","tag-ie","tag-ireland","tag-muscle-composition","tag-nutrition","tag-vitamin-d2","tag-vitamin-d3"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/612546","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=612546"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/612546\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/612547"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=612546"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=612546"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=612546"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}