{"id":620077,"date":"2026-09-10T06:16:09","date_gmt":"2026-09-10T06:16:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/620077\/"},"modified":"2026-09-10T06:16:09","modified_gmt":"2026-09-10T06:16:09","slug":"bruker-advances-whole-organism-3d-imaging-with-enhanced-tissue-clearing-workflows","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/620077\/","title":{"rendered":"Bruker advances whole-organism 3D imaging with enhanced tissue-clearing workflows"},"content":{"rendered":"<p>Bruker Corporation today announced a strategic collaboration with Translucence Biosystems, Inc., a leading provider of tissue\u2011clearing solutions, to expand its workflow for cleared tissue imaging. Through the combined use of Translucence\u2019s\u00a0Universal Tissue Clearing Kit\u00a0alongside Bruker\u2019s light\u2011sheet microscopy and data processing platforms, researchers can move from sample preparation to high-resolution, analysis-ready 3D datasets with greater efficiency and\u00a0ease.<\/p>\n<p><img decoding=\"async\" class=\"rounded-img\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2026\/09\/ImageForNews_846580_17890123624563251.png\" title=\"Bruker advances whole-organism 3D imaging with enhanced tissue-clearing workflows\" width=\"347px\" height=\"700px\" style=\"display: block; margin-left: auto; margin-right: auto;\"\/><br \/>\nMouse brain cleared with Universal Tissue Clearing Kit, label IBA1, a microglia marker. Imaged with the Bruker Luxendo LCS SPIM. Image Credit: Bruker<\/p>\n<p>The\u00a0Universal Tissue Clearing Kit\u00a0is designed to support user-defined antibodies and requires no specialized equipment. Its accessibility and flexibility enable researchers to implement standardized clearing workflows in typical laboratory environments while reducing variability.<\/p>\n<p>Bruker\u2019s\u00a0MuVi\u00a0SPIM\u00a0and\u00a0LCS\u00a0SPIM\u00a0light-sheet microscopes are optimized for 3D imaging of cleared samples, from intricate tissue structures to entire organisms. These systems are supported by a software suite that offers high-speed registration and fusion of large, multi-view datasets. Bruker also provides scalable data management, visualization, and processing with its\u00a0Acquifer\u00a0HIVE\u00a0platform.<\/p>\n<p>Together, these complementary technologies support a streamlined workflow for cleared tissue imaging, enabling researchers to align sample preparation, imaging, and data processing steps more effectively. This approach facilitates consistent generation of high-quality 3D datasets while improving usability, reproducibility, and scalability across a range of biological research applications.<\/p>\n<p>We developed our Universal Tissue Clearing Kit to make high-quality 3D histology more consistent and broadly accessible across different sample types, By combining this foundation with Bruker\u2019s imaging and data capabilities, we can extend the impact of our approach and provide researchers with a more powerful and cohesive solution for whole-organ analysis.\u201d<\/p>\n<p style=\"text-align: right;\">Damian Wheeler, Ph.D., Co\u2011Founder and CEO, Translucence Biosystems<\/p>\n<p>\u201cToday\u2019s researchers are increasingly looking for complete workflows,\u201d added Xiaomei\u00a0Li,\u00a0Ph.D., Senior Vice President and General Manager of Bruker Fluorescence Microscopy. \u201cThis collaboration simplifies 3D imaging workflow, improves reproducibility, and enables researchers to generate meaningful biological insights more efficiently. We believe this partnership will help accelerate discoveries across both basic research and emerging translational applications.\u201d <\/p>\n","protected":false},"excerpt":{"rendered":"Bruker Corporation today announced a strategic collaboration with Translucence Biosystems, Inc., a leading provider of tissue\u2011clearing solutions, to&hellip;\n","protected":false},"author":2,"featured_media":620078,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[6],"tags":[145886,84,61,14529,60,21704,9519,89,138962,80],"class_list":["post-620077","post","type-post","status-publish","format-standard","has-post-thumbnail","category-technology","tag-3d-imaging","tag-brain","tag-ie","tag-imaging","tag-ireland","tag-microscopy","tag-ph","tag-research","tag-sample-preparation","tag-technology"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/620077","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=620077"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/620077\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/620078"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=620077"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=620077"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=620077"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}