{"id":669989,"date":"2026-10-30T15:48:09","date_gmt":"2026-10-30T15:48:09","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/669989\/"},"modified":"2026-10-30T15:48:09","modified_gmt":"2026-10-30T15:48:09","slug":"ict-weekly-rounds-ebola-execution-gaps-a-midge-borne-virus-jumps-to-humans-and-idweek-findings","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/669989\/","title":{"rendered":"ICT Weekly Rounds: Ebola Execution Gaps, a Midge-Borne Virus Jumps to Humans, and IDWeek Findings"},"content":{"rendered":"\n<p class=\"\">The virus has been found in farm animals in 12 countries and on the Channel Island of Jersey. Transmission route and midge species remain unconfirmed, and no second human case has been reported. For IPs, the takeaway is diagnostic awareness of unexplained severe viral disease in immunocompromised patients, along with continued One Health monitoring.<\/p>\n<p>Brucellosis: 875 Hospital Diagnoses and an Open Question About Underdiagnosis<\/p>\n<p class=\"\">A poster presented at IDWeek 2026 analyzed National Inpatient Sample data covering about 147 million US admissions from 2017 to 2020 and identified 875 adults with a diagnosis of brucellosis, roughly 0.6 per 100,000 admissions. Odds were higher among Hispanic patients and in the South and West.<\/p>\n<p class=\"\">The authors noted it is unclear whether brucellosis is underdiagnosed in the US. The findings are associations, not population estimates, but they reinforce the value of a thorough exposure history, including animal contact and unpasteurized dairy.<\/p>\n<p>Ghana Blood Donor Study Finds Reactive Screening Markers in 18.3%<\/p>\n<p class=\"\">Also from IDWeek 2026, a retrospective study of replacement blood donors at a rural hospital in Ghana found that 954 of 5,210 complete records (18.3%) had at least 1reactive marker. Treponemal screening was most common (8.1%), followed by hepatitis C (5.7%), hepatitis B (4.6%), and HIV (1.5%). Reactivity peaked at 26.4% in 2022. As a single-center study without a comparison group, it should not be read as community prevalence, but it highlights the need for confirmatory testing and linkage to care.<\/p>\n<p>Long-Acting HIV Antibodies Advance Toward Phase 2b Data<\/p>\n<p class=\"\">TaiMed Biologics CEO Jimmy Chang, PhD, discussed investigational antibodies TMB-365 and TMB-380 at IDWeek 2026. A phase 1 study of TMB-365 in 25 people reported only mild or moderate adverse events, supporting evaluation of 8- to 12-week dosing, and a 24-week phase 2a study reported no virologic failures among completers. A 48-week phase 2b trial in 83 adults with suppression is ongoing, and efficacy has not yet been established.<\/p>\n<p>Also on the Radar<\/p>\n<p class=\"\">Antifungal innovation: John Rex, MD, of F2G discussed investigational oral antifungal olorofim, which met noninferiority in a phase 3 invasive aspergillosis study with fewer drug-related renal adverse events, and offered career advice for first-time IDWeek attendees. <\/p>\n","protected":false},"excerpt":{"rendered":"The virus has been found in farm animals in 12 countries and on the Channel Island of Jersey.&hellip;\n","protected":false},"author":2,"featured_media":669990,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60],"class_list":["post-669989","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-ie","tag-ireland"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/669989","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=669989"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/669989\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/669990"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=669989"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=669989"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=669989"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}