{"id":68617,"date":"2025-10-09T03:43:07","date_gmt":"2025-10-09T03:43:07","guid":{"rendered":"https:\/\/www.newsbeep.com\/ie\/68617\/"},"modified":"2025-10-09T03:43:07","modified_gmt":"2025-10-09T03:43:07","slug":"brains-of-stranded-dolphins-showed-signs-of-alzheimers-disease-sciencealert","status":"publish","type":"post","link":"https:\/\/www.newsbeep.com\/ie\/68617\/","title":{"rendered":"Brains of Stranded Dolphins Showed Signs of Alzheimer&#8217;s Disease : ScienceAlert"},"content":{"rendered":"<p>Might brain damage linked to  <a href=\"https:\/\/www.sciencealert.com\/go\/IaO\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73015\" data-postid=\"176885\" rel=\"nofollow noopener\" target=\"_self\">Alzheimer&#8217;s<\/a> be one of the reasons dolphins lose their way and end up stranded? It&#8217;s a possibility explored in a new study of 20 common bottlenose dolphins (<a href=\"https:\/\/en.wikipedia.org\/wiki\/Common_bottlenose_dolphin\" rel=\"nofollow noopener\" target=\"_blank\">Tursiops truncatus<\/a>) stranded in the Indian River Lagoon, Florida, between 2010 and 2019.<\/p>\n<p>What&#8217;s more, the researchers behind the study have linked the signs of dolphin neurodegeneration to  <a href=\"https:\/\/www.sciencealert.com\/climate-change\" class=\"lar_link lar_link_outgoing\" data-linkid=\"73046\" data-postid=\"176885\" rel=\"nofollow noopener\" target=\"_self\">climate change<\/a> \u2013 via <a href=\"https:\/\/oceanservice.noaa.gov\/hazards\/hab\/\" rel=\"nofollow noopener\" target=\"_blank\">toxic blooms of algae<\/a> and bacteria that are becoming more frequent and widespread in warmer waters.<\/p>\n<p>An analysis of the brains of the stranded dolphins revealed changes to gene expression that are associated with Alzheimer&#8217;s in humans, as well as <a href=\"https:\/\/www.sciencealert.com\/study-reveals-key-alzheimers-pathway-and-blocking-it-reverses-symptoms-in-mice\" rel=\"nofollow noopener\" target=\"_blank\">damage typical<\/a> of the disease, like <a href=\"https:\/\/www.sciencealert.com\/sky-high-levels-of-alzheimers-protein-found-in-newborns\" rel=\"nofollow noopener\" target=\"_blank\">clumped proteins<\/a>.<\/p>\n<p>Related: <a href=\"https:\/\/www.sciencealert.com\/fat-buildup-in-brain-cells-could-provide-new-target-for-alzheimers-treatment\" rel=\"nofollow noopener\" target=\"_blank\">Fat Buildup in Brain Cells Could Provide New Target For Alzheimer&#8217;s Treatment<\/a><\/p>\n<p>There was a significant difference in the dolphins stranded during algal bloom seasons though: Their brains showed levels of the neurotoxin 2,4-diaminobutyric acid (2,4-DAB) that were a whopping 2,900 times more concentrated than in other dolphins that beached themselves when no algal blooms were around.<\/p>\n<p>It&#8217;s evidence of the harmful effects of blooms filled with <a href=\"https:\/\/en.wikipedia.org\/wiki\/Cyanobacteria\" rel=\"nofollow noopener\" target=\"_blank\">cyanobacteria<\/a>, and it could explain some of the loss of <a href=\"https:\/\/www.sciencealert.com\/your-navigational-skills-are-intricately-linked-to-your-past-research-shows\" rel=\"nofollow noopener\" target=\"_blank\">navigational skills<\/a> and memory that would lead these dolphins to become stranded.<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.newsbeep.com\/ie\/wp-content\/uploads\/2025\/10\/AlgalBloom.jpg\" alt=\"Algal bloom diagram\" width=\"642\" height=\"387\" class=\"wp-image-176888 size-full\"   loading=\"lazy\"\/>The researchers linked algal blooms with dolphin brain damage. (Durden et al., Comms. Biol., 2025)<\/p>\n<p>&#8220;Since dolphins are considered environmental sentinels for toxic exposures in marine environments, there are concerns about human health issues associated with cyanobacterial blooms,&#8221; <a href=\"https:\/\/brainchemistrylabs.org\/news-blog\/2025\/10\/1\/do-stranded-dolphins-have-alzheimers-disease\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> toxicologist David Davis, from the University of Miami.<\/p>\n<p>For context, it&#8217;s important to note that dolphins normally develop brain problems that <a href=\"https:\/\/doi.org\/10.1111\/ejn.15900\" rel=\"nofollow noopener\" target=\"_blank\">look a lot like Alzheimer&#8217;s<\/a> as they get older. We also know that toxins given off by cyanobacteria <a href=\"https:\/\/doi.org\/10.1016\/j.hal.2010.05.002\" rel=\"nofollow noopener\" target=\"_blank\">can harm neurons<\/a> in animals and people, though links to human neurodegenerative diseases are <a href=\"https:\/\/doi.org\/10.1080\/10937404.2017.1297592\" rel=\"nofollow noopener\" target=\"_blank\">still under investigation<\/a>.<\/p>\n<p>The suggestion the team is making now is that these problems might be accelerated and made worse in dolphins <a href=\"https:\/\/theconversation.com\/exposure-to-algae-toxin-increases-the-risk-of-alzheimers-like-illnesses-52981\" rel=\"nofollow noopener\" target=\"_blank\">by harmful algal blooms<\/a>. The study adds details on the neurotoxins doing the damage, the key consequences in the dolphin brains, and the seasonal variations.<\/p>\n<p>&#8220;The co-occurrence of Alzheimer&#8217;s disease neuropathological changes and the natural accumulation of algal toxins observed in dolphins allows a unique opportunity to study the impact of these two converging events on the brain,&#8221; <a href=\"https:\/\/doi.org\/10.1038\/s42003-025-08796-0\" rel=\"nofollow noopener\" target=\"_blank\">write<\/a> the researchers in their published paper.<\/p>\n<p>The risks aren&#8217;t just limited to dolphins, either: these blooms <a href=\"https:\/\/doi.org\/10.1016\/j.scitotenv.2019.134068\" rel=\"nofollow noopener\" target=\"_blank\">are causing harm<\/a> to plenty of other kinds of marine life, which then has knock-on effects going up the food chain, leading eventually to humans.<\/p>\n<p>Past research has <a href=\"https:\/\/www.sciencealert.com\/algae-that-can-cause-memory-loss-found-lurking-in-seafood\" rel=\"nofollow noopener\" target=\"_blank\">already linked<\/a> algal blooms to toxins that can lead to memory loss, which is of course a key characteristic of Alzheimer&#8217;s. If these chemicals get into our food in large enough amounts, that could be a serious problem.<\/p>\n<p>This study looks at dolphins and not humans, but some of the fundamental, Alzheimer&#8217;s-like <a href=\"https:\/\/www.sciencealert.com\/newly-identified-proteins-may-explain-devastating-effects-of-alzheimers\" rel=\"nofollow noopener\" target=\"_blank\">shifts in the brain<\/a> are the same, the researchers note. There&#8217;s no direct link yet, but the signs are there, and that&#8217;s at least worthy of further investigation.<\/p>\n<p>Some of the same researchers have <a href=\"https:\/\/doi.org\/10.1073\/pnas.0404926101\" rel=\"nofollow noopener\" target=\"_blank\">previously looked at<\/a> cyanobacteria and the neurotoxins they produce in cycad trees, finding that these toxins can persist in the environment and can accumulate up the food chain. That&#8217;s a potential pathway where exposure to these toxins might lead to different types of neurodegeneration in human beings, including dementia.<\/p>\n<p>&#8220;Although there are likely many paths to Alzheimer&#8217;s disease, cyanobacterial exposures increasingly appear to be a risk factor,&#8221; <a href=\"https:\/\/brainchemistrylabs.org\/news-blog\/2025\/10\/1\/do-stranded-dolphins-have-alzheimers-disease\" rel=\"nofollow noopener\" target=\"_blank\">says<\/a> Davis.<\/p>\n<p>The research has been published in <a href=\"https:\/\/doi.org\/10.1038\/s42003-025-08796-0\" rel=\"nofollow noopener\" target=\"_blank\">Communication Biology<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"Might brain damage linked to Alzheimer&#8217;s be one of the reasons dolphins lose their way and end up&hellip;\n","protected":false},"author":2,"featured_media":68618,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[103,61,60,2209],"class_list":["post-68617","post","type-post","status-publish","format-standard","has-post-thumbnail","category-health","tag-health","tag-ie","tag-ireland","tag-msft-content"],"_links":{"self":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/68617","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/comments?post=68617"}],"version-history":[{"count":0,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/posts\/68617\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media\/68618"}],"wp:attachment":[{"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/media?parent=68617"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/categories?post=68617"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newsbeep.com\/ie\/wp-json\/wp\/v2\/tags?post=68617"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}