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U.S. M&A poised for rebound in 2026 after two slow years

Over $1 trillion in PE dry powder set to drive deal activity

Interest rate stabilization will fuel leveraged buyouts

Key growth sectors: tech, healthcare, fintech, energy, and industrials

The U.S. mergers and acquisitions (M&A) sector is poised for a significant rebound in 2026 after two years of market turbulence. Elevated interest rates, macroeconomic uncertainty, and supply chain disruptions initially slowed activity. Private equity (PE) firms are sitting on a historic amount of undeployed capital setting the stage for a more aggressive phase of U.S. deal making if inflation cools and the Federal Reserve signals potential rate cuts.

What will be the key drivers of M&A activity in 2026?

Private Equity Deployment Pressure
S.-focused private equity funds were holding over $1 trillion in undeployed capital, as of mid-2025, according to PwC. Pressure is mounting to deploy capital or return it by mid-2025 as funds approach their investment horizons. This will drive both buy-side and sell-side activity, with more add-on acquisitions, secondary buyouts, and recapitalizations in the middle market.
Interest Rate Stabilization
Rising interest rates were a major hurdle for M&A in 2023 and 2024. However, borrowing costs will decrease with the Fed pausing rate hikes in 2025 and indicating a downward trend for 2026. This will make leveraged buyouts more attractive, especially in mid-market transactions.
Corporate Restructuring & Portfolio Rebalancing
Companies, particularly in tech, consumer goods, and healthcare, are refocusing strategies by divesting non-core assets and emphasizing digital transformation. A rise in spin-offs, carve-outs, and strategic acquisitions is expected as companies look to optimize operations and boost shareholder value.
Technological Acceleration
Artificial intelligence (AI), cloud infrastructure, and digital transformation will continue driving M&A. Companies in sectors like SaaS, cybersecurity, and FinTech often lack the internal capacity to innovate quickly and are increasingly acquiring the technologies and talent they need.
Regulatory Environment
Regulatory challenges persist, but legal pushback and court losses could ease restrictions. Mid-sized deals and transactions in less concentrated sectors will likely proceed with fewer obstacles.

What industries are poised for strong M&A activity in 2026?

Technology & AI
Technology will remain the dominant driver of M&A, with AI at the forefront.

Enterprise AI & Automation: Companies such as Microsoft, Oracle, and Salesforce will continue acquiring AI firms to enhance capabilities.
Cybersecurity: Demand for integrated security platforms will surge with evolving cyber threats, especially for endpoint protection and cloud security.
Semiconductors: U.S. efforts to achieve semiconductor independence will fuel M&A activity among chipmakers and AI hardware startups.

Healthcare & Life Sciences
The healthcare sector is transforming rapidly, and consolidation will continue to accelerate.

Biotech & Specialty Pharma: The aging population and demand for chronic disease treatments will drive acquisitions in areas like oncology and neurology.
Digital Health: The rise of telemedicine and AI-driven diagnostics will attract both PE and strategic buyers.
Provider Consolidation: Health systems and hospital groups will merge to reduce costs and expand regional reach. PE firms will also increasingly focus on healthcare roll-ups, such as in dental and dermatology.

Financial Services & FinTech
M&A in the financial sector will be driven by margin compression and digital disruption.

Bank Consolidation: Regional banks will merge to scale and improve digital offerings.
FinTech: Digital banks, payment processors, and lending platforms will continue to be top targets.
WealthTech & InsurTech: Tools for wealth management and insurance digitization will spark niche deals.

Energy & Renewables
The clean energy sector, fueled by the Inflation Reduction Act (IRA), is ripe for consolidation.

Solar & Wind: Larger players will acquire mid-sized developers to expand project pipelines.
Energy Storage: Battery companies and grid tech providers will be hot targets.
Carbon Markets: Companies focused on carbon capture and ESG reporting will see increased interest, as voluntary and regulated carbon markets expand.

Industrial & Infrastructure
S. government spending on infrastructure, defense, and reshoring will drive industrial M&A.

Aerospace & Defense: Military modernization and geopolitical tensions will push defense contractors to pursue strategic acquisitions.
Construction & Engineering: Firms with federal contracts or large-scale infrastructure capabilities will be highly attractive targets for M&A.
Advanced Manufacturing: Robotics and AI-driven manufacturing technologies will be key targets.

Consumer & Retail
S. consumer M&A is shifting focus following a pandemic-era boom.

E-commerce & DTC: Digital-native brands will continue to be acquired by larger players expanding their online presence.
Restaurant & Franchise Models: Consolidation in the fast-casual and QSR sectors will grow, driven by PE interest.
Lifestyle & Wellness: Companies in health, fitness, and sustainable living will attract increasing attention.

Closing thoughts

The mid-market segment, with deals valued between $50M and $500M, is expected to drive most U.S. M&A activity in 2026. These deals are easier to finance, face fewer regulatory hurdles, and integrate more quickly. Mega-deals over $1 billion will still happen, but they will be more selective, especially in tech and pharma, due to potential antitrust concerns.

The U.S. M&A landscape in 2026 is primed for a surge. Private equity firms eager to deploy capital, corporations refocusing for growth, and the cost of capital on the decline point to increased deal activity in the market. Technological innovations in AI, energy, and healthcare will drive acquisitions, while regulatory challenges remain an ongoing concern. However, 2026 offers a unique window of opportunity for strategic buyers and sellers alike.

“The right M&A deal can unlock transformational change and deliver value beyond immediate synergies.” McKinsey & Company

Glenn Ebersole is a registered professional engineer and Business Development Manager at PM Design Group, a nationally licensed A&E firm in West Chester, PA, with 14 offices across the U.S. He can be contacted at [email protected] or 717-575-8572.