Mary Hutton, former chief executive of the NHS Gloucestershire Integrated Care Board, received the honour in the King’s New Year Honours list for her services to health, care and community wellbeing.
Ms Hutton spent more than 30 years in the NHS and was in a senior leadership role in Gloucestershire for 14 years.
Mary Hutton said: “I feel deeply honoured to receive this award.
“It has been a privilege to work alongside such committed staff and supportive partners across Gloucestershire.
“Over the years, we’ve achieved a great deal together for local people, from improving wellbeing to strengthening services.
“This honour reflects those shared efforts over 14 years and I’m truly grateful for the support I’ve had throughout my career.”
During her time in Gloucestershire, Ms Hutton led efforts to strengthen prevention, integrate care, innovate in service delivery, improve workplace culture and maintain sound financial management.
Her focus on practical support for communities and better outcomes for children, older people and those with long-term conditions or disabilities defined her leadership.
Ms Hutton also played a key part in shaping integrated care at both a local and national level, contributing to the development of Integrated Care Systems across England.
Beyond her professional duties, she has volunteered for charitable and community organisations and has a long-standing commitment to young people and youth services.
Professor Dame Jane Cummings, deputy chair of the NHS Gloucestershire Integrated Care Board, said: “Mary’s leadership and vision have had a profound and lasting impact on health and care in Gloucestershire and beyond.
“She has been instrumental in driving collaboration across organisations, improving outcomes for patients and creating a culture where staff feel valued and supported.
“Her influence at a national level helped shape the development of Integrated Care Systems, ensuring that partnership working became central to how we deliver care.
“This honour is a fitting recognition of her exceptional contribution and unwavering commitment to the NHS.”
The CBE is one of the highest honours awarded by the King.