Medscape review
Cancer is one of the leading causes of death among people living with HIV in Brazil. However, with antiretroviral therapy, the cancer profile has shifted: Kaposi sarcoma and AIDS-related lymphomas have declined, whereas cancers such as anal, liver, oropharyngeal, and lung cancers now predominate and may occur at higher rates and at younger ages in this population.
“Non-AIDS-defining cancers have become the main problem,” said Ivan França, MD, PhD, head of the Division of the Infectious Diseases at A.C. Camargo Cancer Center, an oncology hospital in São Paulo, Brazil. “Even with suppressed viral load, the risk accumulates over time and demands ongoing surveillance.”
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