NEW YORK — Maria Semple’s “Go Gentle,” a comic novel about a Stoic philosopher and single mother in Manhattan who finds herself caught up in events that challenge her capacity for acceptance, is Oprah Winfrey’s new book club pick.

“For all those who crave a good page turner , this is one wild ride of a story that carries equal parts wit and wisdom,” Winfrey said in a statement Tuesday. “I learned so much about Stoicism — I laughed out loud for real. And underneath the humor there was always something tender … a quiet truth about relationships, identity, and what it means to find peace with yourself.”