At Leicester General Hospital, the space in the East Midlands Planned Care Centre (EMPCC) will be refurbished and a new home will be built for the Hearing and Balance service.
The Baldwin Lodge at Glenfield Hospital will be refurbished to accommodate occupational health teams currently based at the LRI.
At the LRI, there are plans for a six-storey extension to the Windsor Building and refurbishment of space in the Victoria and Jarvis buildings.
Services will also be relocated from Knighton Street, UHL said, and laboratories will be created for Immunology and Cytogenetics. Inpatient pharmacy services will also be expanded.
UHL chief executive Richard Mitchell said: “The new Urgent Treatment Centre will make it easier for patients to access the right care quickly, reducing waiting times and improving their experience.
“The enabling works will mean we can move services and teams into purpose-built facilities and pave the way for the main construction phase of the NHP in 2032.
“Securing this funding is good news for everyone – colleagues, patients and partners – and is a big step forward in delivering our long-term vision to be leading in healthcare, trusted in communities.”