Shop this week’s Prime Big Deal Days sale to restock your medicine cabinet on a budget!
Supplements are probably one of the most frequent purchases in my Amazon cart. I joke that my counter looks like a pharmacy. But, it’s for a good reason! I’ve lost 80 pounds since taking a GLP-1 and I use supplements to help balance my nutrition when I just don’t want to eat.
Whether you’re on a weight loss journey of your own, or just looking for more ways to add to your nutrition, Amazon’s Prime Big Deal Days is a great time to stock up on your favorites.
Amazon has plenty of supplements on sale for daily support and the USA TODAY Shopping team has scoured the web to find the best discounts on everything from 55% off this B12 supplement, to an exclusive coupon code to save an extra 15% on heart chews.
Amazon Prime Big Deal Days top offers on supplements
Here are some top deals on supplements at Amazon:
Note: This is not medical advice. Everyone’s health journey is different and we suggest consulting your doctor before starting any medications or taking vitamins and supplements.
1. HumanN SuperBeets Heart Chews
HumanN SuperBeets Heart Chews
Looking for a tasty way to boost circulation and energy? Try SuperBeets Heart Chews and save 31% during October Prime Day
2. Bloom Creatine Gummies
Bloom Creatine Gummies
Designed for women, these zero-sugar, grab-and-go gummies support lean muscle growth, strength and cognitive health without the bulk or bloat.
3. Vital Proteins Collagen Peptides Powder
Vital Proteins Collagen Peptides Powder Advanced with Hyaluronic Acid + Vitamin C
150,000 Amazon shoppers gave this collagen powder a five-star review, praising it’s effect on their skin and hair health.
4. Physician’s Choice Probiotics
Physician’s Choice Probiotics 60 Billion CFU
Get a two-month supply of one of the top-rated probiotics on the market!
5. Micro Ingredients Vitamin D3 + K2, 300 Softgels
Micro Ingredients Vitamin D3 + K2, 300 Softgels
This TikTok viral supplement duo work together to support proper calcium absorption to our bones and teeth, while also promoting joint health, immune defense and heart function.
6. Nature’s Bounty Magnesium 500 mg Tablets
Nature’s Bounty Magnesium 500 mg Tablets
While magnesium’s main use is to help maintain bone health, I take it, at the advice of my doctor, to help prevent migraines.
7. Sports Research Triple Strength Omega 3 Fish Oil
Sports Research Triple Strength Omega 3 Fish Oil
Omega 3’s and fish oil are often highly recommended by doctor’s to support a healthier level for triglycerides and cholesterol.
8. Prevagen Regular Strength – 30 Capsules
Prevagen Regular Strength – 30 Capsules
More than 10,000 Amazon shoppers have purchased this brain supplement in the last month.
9. Simply Nature’s Pledge Simply Fruits + Simply Veggies combo pack
Simply Nature’s Pledge Simply Fruits + Simply Veggies combo pack
These supplements are packed with over 42 nutrient-rich fruits and vegetables to support your overall health, improve sleep and boost natural energy levels.
10. Nature’s Bounty Vitamin B12 1000 mcg Supplements
Nature’s Bounty Vitamin B12 1000 mcg Supplements
B12 works to convert food into cellular energy, helping to improve your metabolism and improve energy levels.
More supplements on saleWhat are Amazon October Prime Day 2025 dates?
Amazon’s October Prime Day event will begin on Tuesday, October 7 and run through Wednesday, October 8. The two-day shopping event will feature some of Amazon’s best deals of the season, with discounts spanning top categories like beauty, tech, home and more.
Do I need to be an Amazon Prime member to shop October Prime Day deals?
To ensure you have full access to all of the best Prime Day deals, you’ll want to be an Amazon Prime member. Amazon’s October Prime Day sale has tons of Prime-exclusive discounts on products, and joining Prime helps guarantee you’ll get other perks like fast shipping all year long, access to Prime Video, Prime Reading, Prime Gaming and more.
Amazon Prime Membership
Sign up for an Amazon Prime membership to get exclusive perks and benefits all year.