Doctors say strokes in young adults congenital, advise early genetic screening
Always confident about his health, this man, who worked as a technician and whose name is not revealed,…
Whole-exome sequencing analysis identifies risk genes for schizophrenia
Lally, J. & MacCabe, J. H. Antipsychotic medication in schizophrenia: a review. Br. Med. Bull. 114, 169–179 (2015).…
World Athletics’ mandatory genetic test for women athletes is misguided. I should know – I discovered the relevant gene in 1990
World Athletics president Sebastian Coe recently announced a new rule for women athletes, requiring mandatory genetic tests to…
Bilingualism possible in people with rare genetic condition that normally limits speech
Rett syndrome is a rare neurological condition that disrupts physical and linguistic development, affecting around one in 10,000…
Unravelling the genetics and epigenetics of the ageing tumour microenvironment in cancer
de Magalhaes, J. P. How ageing processes influence cancer. Nat. Rev. Cancer 13, 357–365 (2013). Article PubMed Google…
The Platinum Pedigree: a long-read benchmark for genetic variants
Gonzaga-Jauregui, C., Lupski, J. R. & Gibbs, R. A. Human genome sequencing in health and disease. Annu. Rev.…
Multiancestry brain pQTL fine-mapping and integration with genome-wide association studies of 21 neurologic and psychiatric conditions
Ethics Our study complies with all relevant ethical regulations and was approved by the institutional review boards at…
Scientists find link between genes and ME/chronic fatigue syndrome | ME / Chronic fatigue syndrome
Scientists have found the first robust evidence that people’s genes affect their chances of developing myalgic encephalomyelitis or…
New Method Calculates Rate of Gene Expression in a Cell
Essentially all cells in an organism’s body have the same genetic blueprint, or genome, but the set of…
Genetic Light Switches Revolutionize Disease Control
Imagine being able to flip a light switch to control disease pathways inside a living cell. A team…
Single-nucleus chromatin accessibility profiling identifies cell types and functional variants contributing to major depression
James, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354…
Parent-of-origin effects on complex traits in up to 236,781 individuals
UK Biobank genotype processing We used the UK Biobank Axiom Array data provided in PLINK format39 and converted…