Discovery explains why women face higher risk of Alzheimer’s and multiple sclerosis
New research by UCLA Health has identified a sex-chromosome linked gene that drives inflammation in the female brain,…
Scientists uncover how cellular switches guide memory formation
When we form a memory, brain cells need to deliver supplies to strengthen specific neural connections. A new…
Genetic testing of common and rare variants in dementia patients from a memory clinic | Alzheimer’s Research & Therapy
2023 Alzheimer’s disease facts and figures. Alzheimers Dement 19, 1598–1695 (2023). Campion D, et al. Early-onset autosomal dominant…
Brain somatic mutations in Alzheimer’s disease: linking genetic mosaicism to neurodegeneration | Molecular Neurodegeneration
Zhang XX, Tian Y, Wang ZT, Ma YH, Tan L, Yu JT. The epidemiology of alzheimer’s disease modifiable…
Calcium Supplements Do Not Raise Dementia Risk
Summary: A long-term study of more than 1,400 older women found no evidence that calcium supplements increase dementia…
Scientists use nanoparticles to clear Alzheimer’s brain plaque in mice
1 of 2 | Before-and-after fluorescence microscope images of a mouse brain show red-colored build-ups of toxic amyloid…
What’s my Alzheimer’s risk, and can I really do anything to change it?
A few years ago, my dad was diagnosed with Alzheimer’s disease, just like his older brother and his…
Cell messengers signal amyloid plaque buildup in obese individuals
Obesity has long been acknowledged as a risk factor for a wide range of diseases, but a more…
Microglial glycolytic reprogramming in alzheimer’s disease: association with impaired phagocytic function and altered vascular proximity | Journal of Neuroinflammation
In this study, we analysed HP‒EC tissue from 8 AD patients (mean age: 86.5 years, 5 males, 3…
Blood and brain biomarkers transform how doctors confirm Alzheimer’s disease
By integrating clinical assessment with cutting-edge biomarkers, researchers chart a practical pathway to faster and fairer Alzheimer’s diagnosis,…
The current landscape of Alzheimer’s disease therapeutics
Alzheimer’s disease (AD) is a major global public health concern. Although monoclonal antibody medicines targeting beta-amyloid (Aβ) have…
Dementia tips from a caregiver who’s spent years talking to experts about the disease
Five years ago, I knew very little about dementia. It was a word I might have prefaced with…