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Browsing Tag

Animal Genetics and Genomics

59 posts
BBusiness
Computational investigation of the sequence context of arginine/glycine-rich motifs in the human proteome | BMC Genomics
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Computational investigation of the sequence context of arginine/glycine-rich motifs in the human proteome | BMC Genomics

  • October 6, 2025
Human RG motif statistical comparisons reveal significant differences in physicochemical properties To understand important characteristics or properties of…
BBusiness
SpatPPI: a geometric deep learning model for predicting protein–protein interactions involving intrinsically disordered regions | Genome Biology
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SpatPPI: a geometric deep learning model for predicting protein–protein interactions involving intrinsically disordered regions | Genome Biology

  • October 6, 2025
Data preparation In this section, we introduce the details of the datasets used in this study, including the…
GGenetics
KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease
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KidneyGenAfrica, a pan-African partnership to deliver research and training excellence in genomics of kidney disease

  • October 4, 2025
Precision Healthcare University Research Institute, Queen Mary University of London, London, UK Segun Fatumo, Oyesola Ojewunmi, Rebecca Camenzuli, Christopher Kintu & Claudia Langenberg…
GGenetics
A genetic map of human metabolism across the allele frequency spectrum
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A genetic map of human metabolism across the allele frequency spectrum

  • October 4, 2025
Study design The UKB is a prospective cohort study from the UK that contains more than 500,000 volunteers…
GGenetics
Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology
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Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology

  • October 3, 2025
Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…
GGenetics
Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics
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Exploring the genetic basis of heterosis in eucalypt growth based on transcriptome analysis | BMC Genomics

  • October 3, 2025
Preparation of preliminary data In all samples, the proportion of clean reads was higher than 99.5% (Table S2),…
GGenetics
Spatial architecture of development and disease
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Spatial architecture of development and disease

  • October 1, 2025
Bressan, D., Battistoni, G. & Hannon, G. J. The dawn of spatial omics. Science 381, eabq4964 (2023). Article …
GGenetics
Limited overlap between genetic effects on disease susceptibility and disease survival
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Limited overlap between genetic effects on disease susceptibility and disease survival

  • September 30, 2025
Ethics statement This study was conducted in compliance with the relevant ethical guidelines and approved by the appropriate…
BBusiness
A closed-loop method for precise genome size estimation using HiFi reads | BMC Genomics
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A closed-loop method for precise genome size estimation using HiFi reads | BMC Genomics

  • September 29, 2025
Blommaert J. Genome size evolution: towards new model systems for old questions. Proc Biol Sci. 2020;287(1933): 20201441. PubMed …
TTechnology
Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals | Genome Biology
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Variable efficiency of nonsense-mediated mRNA decay across human tissues, tumors and individuals | Genome Biology

  • September 29, 2025
Individual-level quantification of NMD efficiency We quantified the individual-level NMD efficiency (iNMDeff) by utilizing matched RNA-seq and whole-exome…
BBusiness
Machine learning and statistical inference in microbial population genomics | Genome Biology
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Machine learning and statistical inference in microbial population genomics | Genome Biology

  • September 27, 2025
Blackwell GA, Hunt M, Malone KM, Lima L, Horesh G, Alako BTF, et al. Exploring bacterial diversity via…
TTechnology
Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples | Genome Biology
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Hybrid BAG-seq: DNA and RNA from the same single nucleus reveals interactions between genomic and transcriptomic landscapes in human tumor samples | Genome Biology

  • September 27, 2025
Experimental designSamples We obtained fresh tissue samples of primary tumors from five patients with uterine cancer (Additional file…
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