Nasal COVID vaccine boost increases IgA responses linked to variant neutralisation
A novel nasal booster approach may help close the gap between systemic vaccination and infection-blocking mucosal immunity, offering…
Antibody feedback reshapes B cell selection during immune response
 A collaborative study published in Immunity from the Batista Lab and Liu Lab at the Ragon Institute, together…
Novel antibody 007 targets the elusive HIV envelope epitope
HIV-1 can be neutralized by antibodies which bind to vulnerable structures on the virus surface. One such vulnerable…
Gut microbial butyrate enhances mucosal vaccine antibody responses
A research team from POSTECH and ImmunoBiome in Korea, led by Professor Sin-Hyeog Im, has uncovered a new…
Lab-grown corticospinal neurons offer new models for ALS and spinal injuries
Researchers have developed a way to grow a highly specialized subset of brain nerve cells that are involved…
Antibody-producing plasma cells shape effectiveness of PD-1 immunotherapy
Scientists at the Icahn School of Medicine at Mount Sinai have identified an important immune response that helps…
Targeted Fab fragments dismantle the allergy trigger
Allergic diseases represent a major global health burden, placing significant strain on healthcare systems worldwide. Severe conditions such…
Customizable protein platforms offer new hope for cancer treatment
Precise methods for shredding or repairing and replacing specific cancer-causing proteins in a malignant cell, developed at the…
Researchers discover how Mycoplasma pneumoniae acquires cholesterol from human hosts
A multidisciplinary team has uncovered a key mechanism that allows the human bacterium Mycoplasma pneumoniae-responsible for atypical pneumonia…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Dinutuximab beta plus chemotherapy shrinks neuroblastoma tumors in children
Children with a rare form of cancer called neuroblastoma which hasn’t responded to initial treatment or that has…
Novel antibody suppresses primary tumor growth and spread of triple-negative breast cancer
Triple-negative breast cancer (TNBC) is one of the most aggressive and treatment-resistant forms of breast cancer. It grows…