Targeted therapy doubles progression-free survival in rare bile duct cancer
Results of the ongoing eNRGy trial, a single-arm, multicenter, global phase 2 clinical trial evaluating zenocutuzumab in solid…
Monoclonal antibody shows promise for treating acute respiratory distress syndrome
Doctors have few options for patients who develop a life-threatening lung condition called acute respiratory distress syndrome, or…
Engineered CAR-T cells offer potential rheumatoid arthritis cure
For the 18 million people living with rheumatoid arthritis, disease management currently means a lifetime of injections-a reality…
Heart tissue repair drug may also help repair and regenerate damaged kidney tissues
A drug previously developed at UCLA to help heart tissue repair itself after a heart attack might also…
Apitegromab helps tirzepatide users lose fat while preserving lean mass
A phase 2 trial suggests that blocking myostatin activation may help people taking tirzepatide retain more lean body…
Study reveals how germinal centers consistently produce antibodies
A new study tracking thousands of B cells across more than 100 germinal centers in mice reveals how…
Study finds serious blood-related side effects associated with antibody-drug conjugates
A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated…
Polymer-based immunotherapies enhance tumor targeting and immune activation
Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less…
AI-based generative framework create all-atom models of proteins in motion
Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins. When molecules of a drug…
Alzheimer’s monoclonal antibodies fail to deliver meaningful results
Despite successfully removing amyloid plaques from the brain, widely anticipated antibody therapies fail to deliver meaningful cognitive improvements,…
Study finds long COVID leaves a distinct immune signature in the blood
Blood tests revealed protein patterns tied to long COVID months after infection, while booster shots did not appear…
Maternal antibodies protect newborns from severe E. coli infections, study finds
A multi-center study led by researchers at Cincinnati Children’s sheds surprising new light on why some newborns become…