Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice
A mouse study traces how immune cells activated in the intestine migrate to the dura and persist at…
Could scorpion venom inspire new treatments for liver disease?
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
Scientists traced a hidden immune route that may worsen tau-linked brain damage
Researchers traced an immune pathway from brain-draining lymph nodes to tau-affected tissue, revealing how peripheral immune activity may…
Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
Optimal prostate-specific antigen cutoff linked to improved prostate cancer survival
After treatment for metastatic prostate cancer, a drop in prostate-specific antigen (PSA) levels in the blood is an…
Wistar scientists develop new bispecific T cell engager to target ovarian cancer
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
Memory B cells reveal how nasal vaccines could stop respiratory infections earlier
New insights into lung-resident memory B cells show why the next generation of vaccines may need to protect…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
US study shows updated COVID vaccines cut hospitalization odds by 55%
In an early-season US analysis of more than 111,000 medically attended illness encounters, updated COVID vaccines showed meaningful…
Engineered CAR-T cells offer potential rheumatoid arthritis cure
For the 18 million people living with rheumatoid arthritis, disease management currently means a lifetime of injections-a reality…
PSMA PET detects high-risk prostate cancer bone metastases
Compared to conventional imaging techniques, prostate specific membrane antigen (PSMA) PET imaging provides superior detection of bone metastases…
Predictive model helps tailor PSMA therapy for prostate cancer patients
A new machine-learning approach for prostate-specific membrane antigen (PSMA) treatment of metastatic castration-resistant prostate cancer (mCRPC) could estimate…