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Browsing Tag

Antigen

51 posts
HHealth
Study explains why cancer immunity declines faster in males
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Study explains why cancer immunity declines faster in males

  • October 9, 2026
Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and…
HHealth
New BCR analysis method tracks immune recovery after stem cell transplantation
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New BCR analysis method tracks immune recovery after stem cell transplantation

  • October 6, 2026
A research team led by Associate Professor Yohei Funakoshi, Associate Professor Kimikazu Yakushijin, and Professor Hironobu Minami of…
HHealth
Bile DNA sequencing helps identify hidden pancreatobiliary tumors
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Bile DNA sequencing helps identify hidden pancreatobiliary tumors

  • September 29, 2026
Turning discarded bile into a source of genomic information Distinguishing malignant from benign biliary strictures remains a major…
HHealth
Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system
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Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system

  • September 17, 2026
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but…
HHealth
Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice
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Gut infection leaves long-lasting immune ‘memories’ at the brain’s borders in mice

  • September 10, 2026
A mouse study traces how immune cells activated in the intestine migrate to the dura and persist at…
HHealth
Scorpion venom peptides: Novel therapeutic approaches for inflammatory and hepatic disorders
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Could scorpion venom inspire new treatments for liver disease?

  • September 8, 2026
From blocking inflammatory immune pathways to disrupting hepatitis viruses, scorpion-derived peptides are attracting attention as potential drug candidates,…
HHealth
Study: Priming of CD8+ T cells by peripheral dendritic cells exacerbates tau-mediated neurodegeneration. Image Credit: Antonio Marca / Shutterstock
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Scientists traced a hidden immune route that may worsen tau-linked brain damage

  • September 7, 2026
Researchers traced an immune pathway from brain-draining lymph nodes to tau-affected tissue, revealing how peripheral immune activity may…
HHealth
Immune cells communicate across a continuous, bidirectional circuit between the CNS and periphery. Immune cells from across the body engage CNS tissues and, in turn, are shaped by signals returning from the brain. (Left) Under peripheral equilibrium, immune effectors mobilized from visceral organs, secondary lymphoid organs, hematopoietic tissues, and the peripheral nervous system (PNS) - including CD4+ and CD8+ T cells, B cells, monocytes (top 3 cell types), NK cells, dendritic cells, mast cells, neutrophils, and innate lymphoid cells (bottom cluster of cells) - engage the CNS in a homeostatic dialogue that supports neural cell health, plasticity, and repair, sustaining a protective environment. (Right) Age-associated dysfunction across the same peripheral compartments reshapes this circuit: altered immune effectors enter the CNS and contribute to shifting the local environment toward a degenerative state in which microglia adopt disease-associated programs, astrocytes become reactive, and neurons accumulate pathology. This model underscores how the same circuitry can yield protective or pathogenic outcomes and that neurodegeneration is downstream of dysfunctional brain-immune crosstalk. Study: Neurodegeneration as a dysregulation of neuroimmune crosstalk
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Disrupted brain-immune signaling may help drive neurodegeneration

  • August 24, 2026
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
HHealth
Federal housing support improves survival odds for prostate cancer patients
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Optimal prostate-specific antigen cutoff linked to improved prostate cancer survival

  • August 10, 2026
After treatment for metastatic prostate cancer, a drop in prostate-specific antigen (PSA) levels in the blood is an…
HHealth
Study reveals a new oncogenic role of NBL1 in ovarian cancer metastasis
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Wistar scientists develop new bispecific T cell engager to target ovarian cancer

  • July 21, 2026
Wistar scientists have developed a new type of bispecific T cell engager, or BTE, that is effective against…
HHealth
Memory B cells reveal how nasal vaccines could stop respiratory infections earlier
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Memory B cells reveal how nasal vaccines could stop respiratory infections earlier

  • July 7, 2026
New insights into lung-resident memory B cells show why the next generation of vaccines may need to protect…
HHealth
Regular mammograms linked to longer survival in women over 80
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New breast cancer classification system predicts immunotherapy response success

  • July 3, 2026
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
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