Natural sex reversal imparts permanent compositional changes to the swamp eel gonadal microbiome | Microbiome
Fish maintenance and trial design The sourcing of swamp eel and the rearing procedures employed in this study…
Unlocking the regulatory code of RNA: launching the Human RNome Project | Genome Biology
The Human RNome Project aims to ensure consistent and reproducible outcomes in RNA sequencing and modification studies by…
iNOME-seq: in vivo simultaneous genome-wide mapping of chromatin accessibility, nucleosome positioning, DNA-binding protein sites, and DNA methylation in Arabidopsis | Genome Biology
Plant lines and growth conditions The plant lines used in this study were derived from A. thaliana wild-type…
MultiModalGraphics: an R package for graphical integration of multi-omics datasets | BMC Bioinformatics
MultiModalGraphics is an R/Bioconductor package that leverages object-oriented S4 classes to visualize multimodal biological data with embedded statistical…
Topology-aware functional similarity: integrating extended neighborhoods via exponential attenuation | BMC Bioinformatics
Experiment datasets This study systematically evaluates protein-protein interaction (PPI) networks from four model organisms: Saccharomyces cerevisiae, Arabidopsis thaliana,…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
World Record Set For Fastest Genome Sequencing | Health
Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…
SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology
Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…
SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics
Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…
A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology
K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…
Structural and evolutionary features of red algal UV sex chromosomes | Genome Biology
To define the male and female haplotypes of the sex-determining locus in Gracilaria species, we leveraged male reference…
SpatPPI: a geometric deep learning model for predicting protein–protein interactions involving intrinsically disordered regions | Genome Biology
Data preparation In this section, we introduce the details of the datasets used in this study, including the…