Bioinformatics - Israel News Beep

iNOME-seq: in vivo simultaneous genome-wide mapping of chromatin accessibility, nucleosome positioning, DNA-binding protein sites, and DNA methylation in Arabidopsis | Genome Biology

October 22, 2025

Plant lines and growth conditions The plant lines used in this study were derived from A. thaliana wild-type…

MultiModalGraphics: an R package for graphical integration of multi-omics datasets | BMC Bioinformatics

October 21, 2025

MultiModalGraphics is an R/Bioconductor package that leverages object-oriented S4 classes to visualize multimodal biological data with embedded statistical…

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Topology-aware functional similarity: integrating extended neighborhoods via exponential attenuation | BMC Bioinformatics

October 21, 2025

Experiment datasets This study systematically evaluates protein-protein interaction (PPI) networks from four model organisms: Saccharomyces cerevisiae, Arabidopsis thaliana,…

GGenetics

World Record Set For Fastest Genome Sequencing | Health

October 20, 2025

Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…

GGenetics

October 17, 2025

Key Takeaways Researchers have set a new world record for fastest whole human genome sequencing The team completed…

GGenetics

SPAmix: a scalable, accurate, and universal analysis framework for large-scale genetic association studies in admixed populations | Genome Biology

October 16, 2025

Model residuals of linear regression and logistic regression Linear regression and logistic regression are regular models to fit…

GGenetics

SAGPEK: fast and flexible approach to identify genotypes of Sanger sequencing data | BMC Bioinformatics

October 14, 2025

Software architecture SAGPEK mainly processes Sanger sequencing results of two kinds of samples: diploids such as humans and…

GGenetics

A novel gene expression stability metric to unveil homeostasis and regulation | Genome Biology

October 10, 2025

K-proportion and gene homeostasis Z-Index identify regulatory genes As cells of the same type and in the same…

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Structural and evolutionary features of red algal UV sex chromosomes | Genome Biology

October 7, 2025

To define the male and female haplotypes of the sex-determining locus in Gracilaria species, we leveraged male reference…

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SpatPPI: a geometric deep learning model for predicting protein–protein interactions involving intrinsically disordered regions | Genome Biology

October 6, 2025

Data preparation In this section, we introduce the details of the datasets used in this study, including the…

GGenetics

Incorporating additive genetic effects and linkage disequilibrium information to discover gene-environment interactions using BV-LDER-GE | Genome Biology

October 3, 2025

Model overview We consider the following model to incorporate both additive and interaction effects: $${Y}_{i}={\sum }_{j=1}^{M}{G}_{ji}{\beta }_{j}+{\sum }_{j=1}^{M}{S}_{ji}{\gamma…

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Boosting K-nearest neighbor regression performance for longitudinal data through a novel learning approach | BMC Bioinformatics

September 30, 2025

Variable-trajectory Let $y_{it} \in {\mathbb{R}}$ denote the observed response value for the subject \(i \in \left\{ {1, \ldots…