Evaluating the robustness and readiness of large frontier models in health AI applications
Singhal, K. et al. Large language models encode clinical knowledge. Nature 620, 172–180 (2023). Article CAS PubMed PubMed…
Large reasoning models as thinking machines for medicine
Jaech, A. et al. OpenAI o1 system card. Preprint at https://arxiv.org/abs/2412.16720 (2024). Guo, D. et al. DeepSeek-R1 incentivizes…
Apitegromab for lean mass preservation during tirzepatide-induced weight loss: a randomized, double-blind, placebo-controlled phase 2 trial
Trial details EMBRAZE was a randomized, double-blind, placebo-controlled, phase 2 trial (NCT06445075) conducted at seven sites in the…
Medically tailored meals receipt and healthcare utilization and costs in Massachusetts’ Medicaid demonstration
Study design and setting We used a propensity score weighted, difference-in-difference analysis of adult MassHealth members with one…
The promise of adaptive health in the United Arab Emirates and beyond
Department of Medicine, Johns Hopkins University, Baltimore, MD, USA Andrew P. Feinberg Department of Biomedical Engineering, Johns Hopkins…
Sensor wide association studies in digital medicine
Data quality and standardization Wearable data can be noisy, incomplete, and inconsistent across devices. Even within a single…
Genetic variation in transgenerational immune priming and its association with fecundity and body mass in the mealworm beetle Tenebrio molitor
Beetle cultures Tenebrio molitor used in this study originated from an outbred stock culture of more than 100,000…
AI-induced never-skilling in medical education
Bajwa, J., Munir, U., Nori, A. & Williams, B. Artificial intelligence in healthcare: transforming the practice of medicine.…
Enabling secure discovery in trusted research environments with improved tooling
Competing interests V.J.S. was previously a research scholar for OFH. M.C.M. is a research ambassador for OFH, is…
Fetal monitoring for high-risk pregnancies using a wearable ultrasound patch
Woodward, P. J., Kennedy, A. & Sohaey, R. Diagnostic Imaging: Obstetrics 4th edn (Elsevier, 2021). Hutter, D., Kingdom,…
Bioinformatics accelerates discovery of marine-derived bioactive therapeutic peptides
Marine organisms have evolved a remarkable arsenal of host-defense peptides under conditions of extreme variability and constant pathogen…
Advancing conversational diagnostic AI with multimodal reasoning
This work advances the diagnostic capabilities of the multimodal AMIE system4,5 by integrating multimodal perception, enabling it to…