Integrated signatures define mutational processes in prostate cancer
PPCG cohort, WGS and variant calling We used data from the PPCG consortium of primary prostate cancer samples…
Baseline plasma-informed circulating tumor DNA analyses comparing multiplex digital PCR and NGS for longitudinal monitoring in Hodgkin lymphoma
Despite excellent cure rates in Hodgkin lymphoma (HL) [1], 10–15% of patients experience primary treatment failure or long-term…
Synthetic lethality in cancer drug discovery: challenges and opportunities
Hartwell, L. H., Szankasi, P., Roberts, C. J., Murray, A. W. & Friend, S. H. Integrating genetic approaches…