New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
Study shows DHPS enzyme controls macrophage maturation across multiple organs
A new study led by researchers at the Johns Hopkins Kimmel Cancer Center, its Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns…
Bacterial metabolite enhances immune checkpoint therapy against lung cancer
UF Health Cancer Institute researchers have discovered a small compound produced naturally by gut bacteria that doubled the response…
UVA researcher wins $700,000 for promising ovarian cancer research
Promising ovarian cancer research by Melanie Rutkowski, PhD, at the University of Virginia Comprehensive Cancer Center has won…
Review highlights emerging role of tumor MHC-II in shaping cancer immunotherapy outcomes
Cancer immunotherapy has transformed cancer treatment, yet many patients experience limited or short-lived responses due to immune evasion,…
Dietary restriction boosts antitumour immunity by rewiring T cell metabolism
By elevating ketone-driven energy pathways inside CD8+ T cells, dietary restriction steers them away from exhaustion and toward…
Timing Is Everything In Cancer Immunotherapy, Experts Say | Health
Key Takeaways Cancer immunotherapies might work better if given earlier in the day Lung cancer patients had better…
Neoantigens-loaded DC vaccines show strong potential to overcome tumor resistance
Despite the success of immune checkpoint inhibitors in revolutionizing oncology, their benefits remain limited to a small fraction…
Viral immunologist taps ‘incredible potential’ of immune system
Viral immunologist Paul Thomas, PhD, is working to turn the “incredible potential” of the immune system into real-life…
Innovative gene engineering and drug delivery systems for dendritic cells in cancer immunotherapy | Journal of Biomedical Science
Yang YL, Yang F, Huang ZQ, Li YY, Shi HY, Sun Q, et al. T cells, NK cells,…