Unstable immune cells linked to severe cancer immunotherapy side effects
Scientists at the University of Pittsburgh uncovered the unstable immune cells that can cause up to 40% of…
Study explains why cancer immunity declines faster in males
Lutz Menzel, PhD, formerly of the Department of Radiation Oncology within the Mass General Brigham Cancer Institute, and…
Scientists reveals how cancer-causing p53 mutations remain invisible to the immune system
One of the biggest challenges in cancer immunotherapy may not be that immune cells are too weak, but…
New ultrasound technique breaches blood brain barrier to treat gliomas
In a promising sign for the potential of focused sound waves to improve care for brain tumors, UVA…
New strategy combines cancer immunotherapy and gene therapy in a single nanoparticle
Cancer cells survive by hiding from the immune system’s surveillance. A KAIST research team has developed a new…
New breast cancer classification system predicts immunotherapy response success
The advent of immune checkpoint inhibitors (ICIs) has marked a paradigm shift in cancer treatment, yet a significant…
Neutrophils reduce the effectiveness of cancer immunotherapy in mice
A type of white blood cell in the immune system, known as neutrophils, can make cancer immunotherapy less…
Polymer-based immunotherapies enhance tumor targeting and immune activation
Conventional immune checkpoint inhibitors, such as anti-PD-1/PD-L1 and anti-CTLA-4 antibodies, can reinvigorate T cells but typically benefit less…
Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity
Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset…
Researchers uncover how bacterial toxin damages colon lining cells to trigger cancer
Since a landmark 2009 study, researchers have known that a common gut bacterium, Bacteroides fragilis, drives colon tumor…
A new combined therapy to boost the immune system against cancer
Cancer immunotherapy is built on a simple but powerful idea: the immune system can recognize and destroy cancer…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…