Engineered Listeria boosts innate immunity against cancer
After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system…
Power of Tiny Molecular ‘Flycatcher’ Surprises Through Disorder
BYLINE: Jenny Green Newswise — For decades, scientists assumed that order drives efficiency. Yet in the bustling machinery…
Why cancer can come back years later — and how to stop it
When Lisa Dutton was declared free of breast cancer in 2017, she took a moment to celebrate with…
Epigenetic plasticity in germinal center B cells may help explain lymphoma origins
Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During…
Blocking a ‘gerozyme’ reverses cartilage loss in mice
An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in…
Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium
Mika, J. et al. Symptom-based early-stage differentiation between SARS-CoV-2 versus other respiratory tract infections—Upper Silesia pilot study. Sci.…
Fusobacterium nucleatum-reprogrammed adipocytes promote tumor cisplatin resistance through the CCL2-CCR2 axis in the necrotic metastatic neck nodes of head and neck carcinoma | Cell Communication and Signaling
Hanai N, Ozawa T, Hirakawa H, et al. The nodal response to chemoselection predicts the risk of recurrence…
Cutting-edge treatments in amyotrophic lateral sclerosis: the role of molecular pathogenesis in targeted therapies | Stem Cell Research & Therapy
Feldman EL, Goutman SA, Petri S, Mazzini L, Savelieff MG, Shaw PJ, et al. Amyotrophic lateral sclerosis. Lancet.…
An arthropod transporter IsOATP4056 exerts inhibitory effect on its interacting membrane protein to facilitate rickettsial pathogen survival in ticks | Cell Communication and Signaling
Neelakanta G, Sultana H. Transmission-Blocking vaccines: focus on Anti-Vector vaccines against Tick-Borne diseases. Arch Immunol Ther Exp (Warsz).…
Discovery of sequence-driven DNA methylation offers new path for epigenetic engineering
All the cells in an organism have the exact same genetic sequence. What differs across cell types is…
Efficacy of Extracellular Vesicles Derived From Mesenchymal Stromal Cells in Regulating Senescence: In Vitro and in vivo Insights
BACKGROUND Newswise — Extracellular vesicles derived from mesenchymal stromal cells (MSC-EVs) can be used for anti-aging therapy and…
Common IVF test misses some genetic abnormalities in embryos
Coloured light micrograph of a human embryo after in vitro fertilisation ZEPHYR/SCIENCE PHOTO LIBRARY During in vitro fertilisation…