Brain organoids reveal how Alu-mediated gene deletion can lead to neurodegeneration
Brain diseases, including dementia, have long been studied using experimental animals such as mice. However, differences between the…
Fleeting interactions between membrane sugar chains control cell division
Acting as an armor, a scaffold, and a communication platform in one, our cells’ plasma membrane lies at…
Computer model could streamline design of protein degraders
A team of Weill Cornell Medicine investigators has developed a computer model that will help scientists more efficiently…
New platform enables large-scale production of custom proteins
Scientists have been hard at work for more than 20 years to instruct biological systems, such as E.…
Study reveals why diffuse midline glioma develops in brain midline regions
Scientists at St. Jude Children’s Research Hospital have shown that specific brain cells respond differently to the H3.3…
Tea, berries and dark chocolate featured in a diet linked to lower Parkinson’s risk
From tea and berries to dark chocolate, researchers tracked how a flavonoid-rich dietary pattern relates to Parkinson’s disease…
Targeting cyclin-dependent kinases offers new pathways for cancer therapy
Cancer is the second leading cause of death in Germany. In the search for new therapeutic approaches that…
Satellite DNA acts as a barcode for matching chromosome pairs
The body cells of humans and animals contain a double set of chromosomes. One half of the genetic…
Disrupted brain-immune signaling may help drive neurodegeneration
From gut-primed T cells to microglial signaling and persistent gene-regulatory states, researchers map an intricate immune network that…
A striking immune cell pattern emerges around a person’s 100th birthday
Rare immune cells found at strikingly high levels in people who live beyond 110 reveal an unusual pattern…
Deliverome project maps cell surface proteins for better drug delivery
For a new drug to work in the human body, it must make its way to the exact…
New review highlights spatial technologies in advanced brain mapping
Understanding how molecular changes shape brain function and disease requires more than measuring genes in bulk tissue. The…