Blocking fructose metabolism may improve brain tumor immunotherapy response
Northwestern Medicine scientists have discovered that specialized immune cells within the glioblastoma tumor metabolize fructose to suppress immune…
Scientists turn plastic waste into Parkinson’s drug levodopa using engineered bacteria
A novel engineered microbial system transforms discarded plastic into a frontline Parkinson’s treatment, offering a glimpse into a…
Study uncovers how tuberculosis bacteria fuel themselves during infection
Researchers at The Hospital for Sick Children (SickKids) have uncovered how the bacteria that causes tuberculosis fuels itself during infection, providing new insights…
Study reveals dual role of PFK enzyme in metabolism and cell cycle progression
A metabolic enzyme studied for over seven decades has a hidden second function – it can unwind RNA…
Computational model predicts telomere length from biopsy images
A new computational tool infers changes occurring at the ends of the chromosomes housing our DNA. It does…
Vitamin B2 metabolism helps cancer cells resist ferroptosis
A lack of vitamin B2 makes tumor cells more susceptible to a unique form of cell death. This…
Study reveals how disordered proteins function without stable structure
A new LMU study shows how proteins function reliably even without a stable 3D structure – and the…
New insights highlight multifaceted roles of CD4+ T cells in tumor immunity
For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor…
FDA-approved drug fedratinib enhances communication between cellular organelles
Cells behave like cities and organelles carry out infrastructural roles: Mitochondria are powerhouses, the endoplasmic reticulum serves as…
SonoPIN technology boosts intracellular delivery of large cancer drugs
Engineers at Duke University have demonstrated a technique that uses microbubbles and ultrasound to help relatively large cancer…
Gene mutation that aids high-altitude survival could repair myelin sheath damage
A genetic mutation that helps animals like yaks and Tibetan antelopes survive at high altitudes may hold the key to repairing…
Pen-strep treatment rewires mechanical sensing in immune cells
Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to…