New catalog identifies dozens of plasma membrane repair proteins
In the evolutionary history of life, the ability of a cell to separate its inner world from the…
Single receptor PAR1 controls opposing responses in blood vessels
Researchers at the University of California San Diego have uncovered how a single protein triggers two opposite responses…
Long-read whole genome sequencing uncovers new genetic variants linked to autism
Researchers at the University of California San Diego have identified new genetic variants associated with autism spectrum disorder…
Most pandemic viruses show little adaptation before infecting humans
A new University of California San Diego study published in Cell challenges a long-standing assumption about how animal…
New CRISPR technique boosts mitochondrial function to treat heart failure
After a heart attack, the heart struggles to recoup and maintain energy. One third of patients develop heart…
Biomimetic platform enhances CAR T therapy for relapsed and refractory leukemia
Chimeric antigen receptor T (CAR T) cell therapy represents a milestone in leukemia treatment. CAR T works by…
FOXJ3 gene identified as the critical link between abnormal brain development and epilepsy
Researchers have discovered that mutations in the FOXJ3 gene act as a “master switch” failure, disrupting how the…
Understanding PIEZO2 mutations and sensory disorders
Every time we feel a gentle tap on the skin, specialized nerve cells convert that physical force into…
Unmasking the hyperactive circuitry of early Alzheimer’s
Neuroscientists at King’s College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer’s…
New peptide fragments teach the gut to tolerate food
In little moments like when sipping coffee or licking an ice cream cone, it doesn’t seem like your…
How somatic mutations shape disease and reveal new drug targets
Scientists reveal how evolution within our own tissues can drive disease, protect cells, and uncover hidden therapeutic targets…
Scientists discover how herpes simplex virus softens cells to multiply faster
Herpes simplex virus partially liquifies the tightly packed, gel-like interior of human cell nuclei to copy itself faster,…